| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC26104 | UVI 2008 | A RARβ/γ agonist originated from TTNPB, is also a selective inhibitor of aldo-keto reductase family member 1B10 (AKR1B10) with IC50 of 6.1 uM. |
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| DC22985 | BMS-948 | A RARβ-selective agonist that exhibits a full transcriptional agonistic activity and activating RARβ as efficiently as the reference agonist TTNPB. |
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| DC7350 | 9-methyladenine | A receptor adenine derivative binding membrane brain animal cell line.For the detailed information of 9-methyladenine, the solubility of 9-methyladenine in water, the solubility of 9-methyladenine in DMSO, the solubility of 9-methyladenine in PBS buffer, the animal experiment (test) of 9-methyladenine, the cell expriment (test) of 9-methyladenine, the in vivo, in vitro and clinical trial test of 9-methyladenine, the EC50, IC50,and Affinity of 9-methyladenine, Please contact DC Chemicals.. |
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| DC23842 | L-783277 | A resorcylic lactone type covalent kinase inhibitor that inhibits ALK1 with IC50 of 125 nM, also inhibits FLT3, VEGFR2, VEGFR3, MEK2 with IC50 of 1-10 nM.. |
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| DC24096 | Dabigatran ethyl ester | A reversible and selective, direct thrombin inhibitor (DTI) with Ki value of 4.5 nM. |
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| DC22367 | Bromethalin | A rodenticide that poisons the central nervous system by uncoupling mitochondrial oxidative phosphorylation, which causes a decrease in adenosine triphosphate (ATP) synthesis.. |
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| DC21011 | KP-1019 sodium salt | A ruthenium complex anticancer agent that is useful for metastatic tumors and cis-platin resistant tumors. |
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| DC20822 | BMT-052 | A second generation, orally biovailable pan-genotypic HCV NS5B polymerase inhibitor with EC50 of 1-10 nM. |
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| DC24180 | Cetirizine | A second-generation antihistamine that acts as a selective H1 receptor antagonist. |
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| DC22589 | Eltanexor | A second-generation SINE, orally bioavailable Exportin 1 (XPO1,CRM1) inhibitor with markedly reduced brain penetration compared to selinexor (30-fold less). |
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| DC23944 | K-7174 | A selctive small molecule inhibitor of the transcription factor GATA-binding protein 2 (GATA2). |
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| DC23943 | K-7174 dihydrochloride | K-7174 dihydrochloride is a selctive small molecule inhibitor of the transcription factor GATA-binding protein 2 (GATA2). |
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| DC20568 | Tec Kinase-IN-6 | A selecitve small molecule toward Tec kinase-mediated tyrosine phosphorylation of FGF2 with IC50 of 8.9 uM. |
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| DC23996 | Capadenoson | Capadenoson is a selective agonist of adenosine-A1 receptor. |
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| DC22954 | MG-624 | MG624 is a potent and selective neuronal α7 nAChR antagonist with a Ki of 106 nM. |
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| DC21853 | Ogerin | A selective GPR68 positive allosteric modulator (pEC50=6.83) with minimal PAM activity at the related proton-sensing GPCRs GPR4 and GPR65. |
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| DC20596 | O-phenanthroline | A selective inhibitor of 26S proteasome subunit Rpn11 with IC50 of 10±2 uM. |
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| DC22980 | ND-336 | A selective inhibitor of the gelatinases MMP2 and MMP9 and MMP13 with Ki of 85, 150 and 120 nM, respectively. |
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| DC21127 | HT-0411 | A selective monoamine oxidase B (MAO-B) inhibitor with IC50 of 1.4 uM, with less potency for MT-1 and MT-2. |
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| DC23235 | Flupirtine | A selective neuronal potassium channel (KCNQ/KV7 channel) activator that also has indirect NMDA receptor antagonist and GABAA receptor modulatory properties. |
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| DC26069 | SR-11237 | SR-11237 is a selective pan retinoid X receptor (RXR) agonist with no retinoid A receptor (RAR) activity. . |
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| DC22616 | CJ-42794 | A selective prostaglandin E receptor subtype 4 (EP4) antagonist with pKi of 8.5. |
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| DC20567 | Tec Kinase-IN-21 | A selective small molecule toward Tec kinase-mediated tyrosine phosphorylation of FGF2 with IC50 of 11.7 uM. |
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| DC20566 | Tec Kinase-IN-14 | A selective small molecule toward Tec kinase-mediated tyrosine phosphorylation of FGF2 with IC50 of 7.0 uM. |
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| DC25014 | Cysmethynil | A selective small-molecule inhibitor of tisoprenylcysteine carboxyl methyltransferase (Icmt) with IC50 <200 nM, does not inhibit other enzymes (farensyltransferase, geranylgeranyltransferase type I, and Rce1) at concentrations up to 50 uM. |
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| DC22924 | 3M-002 | A selective TLR8 agonist that induces activation of NF-κB at 0.4 uM. |
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| DC20306 | AMTB hydrochloride | A selective TRPM8 channel blocker with pEC50 of 6.91 in Ca(2+) influx assay, with no activity for TRPV4 (pEC50<4.6). |
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| DC23226 | Guanfacine | A selective α2A receptor agonist that can reduce peripheral sympathetic outflow and thus cansues a reduction in peripheral sympathetic tone. |
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| DC24156 | Metoprolol | A selective β1 receptor blocker used in treatment of several diseases of the cardiovascular system, especially hypertension.. |
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| DC7029 | SC-26196 | A selective Δ6 desaturase inhibitor that displays selectivity over Δ5 and Δ9 desaturases |
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