| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC26107 | TRV0109101 hydrochloride | A selective, G protein-biased µ-opioid receptor agonist, does not promote the development of opioid-induced mechanical allodynia (OIMA) and rapidly reverses allodynia in vivo.. |
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| DC26103 | TRV0109101 | A selective, G protein-biased µ-opioid receptor agonist, does not promote the development of opioid-induced mechanical allodynia (OIMA) and rapidly reverses allodynia in vivo.. |
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| DC21728 | TAK-070 | A selective, nonpeptidic, noncompetitive BACE1 inhibitor with IC50 of 3.15 uM in cell-free assays. |
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| DC20995 | EP009 | A selective, orally active JAK3 inhibitor that reduces IL-2-mediated JAK3 tyrosine phosphorylation with cellular IC50 of 10-20 uM. |
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| DC20287 | δ-secretase inhibitor 11 | A selective, orally bioactive and brain permeable δ-secretase (AEP. |
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| DC22971 | CDE 096 | A selective, reversible, high-affinity PAI-1 inhibitor that prevents PAI-1 from inactivating tPA and uPA with similar potency (IC50=30 and 25 nM, respectively). |
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| DC21780 | UNC-3230 | A selective, small molecule inhibitor of PIP5K1C with IC50 of 41 nM, does not ihibits other lipid kinases including PI3Ks. |
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| DC21400 | NS-1209 | A selective, water-soluble, in vivo long-lasting AMPA antagonist with Ki of 43 nM. |
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| DC22451 | AQX 1125 acetate | A sepecific, orally bioavailable SHIP1 activator with no effect on functional androgen, oestrogen, oestrogen-related receptor α, glucocorticoid, mineralocorticoid and progesterone receptor at 30 uM. |
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| DC23981 | BCX-1470 methanesulfonate | A serine protease inhibitor that inhibits the esterolytic activity of factor D (IC50=96 nM) and C1s (IC50=1.6 nM). |
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| DC22666 | Levosalbutamol | A short-acting β2 adrenergic receptor agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).. |
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| DC23231 | Levalbuterol tartrate | A short-acting β2 adrenergic receptor agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).. |
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| DC22828 | DBCO-Amine | A simple DBCO-containing building block used to derivatize carboxyl groups in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) with DBCO moiety through a stable amide bond. |
|
| DC23011 | Shz-1 | A small cardiogenic molecule that potently induces Nkx2.5 and a subset of other cardiac markers, including myocardin, troponin-I, and sarcomeric α-tropomyosin (SαTM) in a variety of different stem/progenitor cells. |
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| DC25018 | Shz-3 | A small cardiogenic molecule that potently induces Nkx2.5 and a subset of other cardiac markers, including myocardin, troponin-I, and sarcomeric α-tropomyosin (SαTM) in a variety of different stem/progenitor cells. |
|
| DC21818 | MIN-117 | A small molecule 5-HT1A and 5-HT2A receptor antagonist and inhibitor of serotonin and dopamine reuptake, also possess affinity for the α1A- and α1B-adrenergic receptors.. |
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| DC22831 | VU 0038882 | A small molecule activator of S. aureus HssRS (heme sensor system) that induces endogenous heme biosynthesis by perturbing central metabolism. |
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| DC23648 | TKN2 | A small molecule allosteric inhibitor of TREK channels with IC50 of 3.8, 1.7 and 10.3 uM for TREK-1, TREK-2 and TRAAK, respectively.. |
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| DC23585 | 28NH | A small molecule allosteric inhibitor of TREK channels with IC50 of 5.0, 5.0 and 11.8 uM for TREK-1, TREK-2 and TRAAK, respectively.. |
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| DC23582 | TKN1 | A small molecule allosteric inhibitor of TREK channels with IC50 of 6.5, 4.4 and 15.7 uM for TREK-1, TREK-2 and TRAAK, respectively.. |
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| DC23241 | TAME | A small molecule anaphase-promoting complex/cyclosome (APC/C) inhibitor that binds to the APC preferentially suppresses APC/C(Cdc20) rather than APC/C(Cdh1). |
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| DC11655 | ABO dihydrochloride | A small molecule ANXA7 GTPase activity inhibitor, induces mouse ESCs differentiation to VECs. |
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| DC24017 | SMER-18 | A small molecule autophagy enhancer that induces autophagy independently of rapamycin in mammalian cells and enhances the clearance of autophagy substrates such as mutant huntingtin and A53T alpha-synuclein. |
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| DC23190 | LM22A-4 | A small molecule BDNF mimetic that act as a direct and specific partial agonist of TrkB (EC50=200-500 pM), but not p75. |
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| DC25021 | Endosidin-2 | A small molecule binds to the EXO70 (exocyst component of 70 kDa) subunit of the exocyst complex (Kd=253 uM), resulting in inhibition of exocytosis and endosomal recycling in both plant and human cells and enhancement of plant vacuolar trafficking.. |
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| DC22842 | DMJ-I-228 | A small molecule CD4-mimetic that binds gp120 and blocks CD4 binding, inhibits HIV-1 entry with IC50 of 86.9 uM.. |
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| DC22524 | ZSET1446 | A small molecule cognitive enhancer that potentiates acetylcholine-mediated facilitation of inhibitory synaptic transmission in the hippocampal neurons. |
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| DC20445 | Me6TREN | A small molecule Cu complexing ligand used for atom transfer radical polymerization (ATRP). |
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| DC21067 | TB-03 | A small molecule Grb2 SH2 domain binding antagonist that synergistically enhances inhibition of K562 leukemia cell proliferation by imatinib (CI=0.774). |
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| DC22843 | DDX3-IN-16d | A small molecule inhibitor (IC50=0.3 uM) of DEAD-box polypeptide 3 (DDX3), a human host factor required for the replication of several DNA and RNA viruses. |
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