| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DCC4779 | Slm6071469 | Novel potent SphK2-selective inhibitor (Ki = 89 nM, 73-fold SphK2-selective) with validated in vivo activity |
|
| DCC4780 | Slp120701 | Novel SphK2-selective inhibitor with improved half-life to 8 h in mice |
|
| DCC4781 | Slp7111228 | Novel selective SphK1 inhibitor |
|
| DCC4782 | Slr080811 | Novel SphK2-selective inhibitor |
|
| DCC4783 | Slupp-225 | Novel efflux pump inhibitor (EPI) |
|
| DCC4784 | Slupp-417 | Novel efflux pump inhibitor (EPI) |
|
| DCC4785 | Sm-130686 | Potent, orally-active agonist of the ghrelin/growth hormone secretagogue receptor (GHSR) and growth hormone secretagogue |
|
| DCC4786 | Sm-131 | Novel Potent, Cell-Permeable, Conformationally Constrained Second Mitochondria Derived Activator of Caspase (Smac) Mimetic |
|
| DCC4787 | Sm-337 | Non-peptidic Smac mimetic, binding to XIAP, cIAP-1 and cIAP-2 proteins with higher affinities in cell growth inhibition in the MDA-MB-231 cell line |
|
| DCC4788 | Sm4487 | Novel potent and selective inhibitor of galactokinase (GALK1) |
|
| DCC4789 | Sma-12b | Novel inhibitor of IL-1 |
|
| DCC4790 | Smac127 | Proapoptotic and anti-inflammatory agent, inducing apoptosis by inhibiting apoptosis proteins (IAPs) |
|
| DCC4791 | Smapp1 | Novel activator of PP1, inducing HIV-1 transcription, reactivation of latent HIV-1 in chronically infected cells, and CDK9 phosphorylation |
|
| DCC4792 | Smart-h | Potent inhibitor of microtubule polymerization |
|
| DCC4793 | Smart-oh | Potent inhibitor of microtubule polymerization |
|
| DCC4794 | Smases D Inhibitor-1 | Novel inhibitor of Loxosceles sphingomyelinases D (SMases D) |
|
| DCC4795 | Smases D Inhibitor-5 | Novel inhibitor of Loxosceles sphingomyelinases D (SMases D) |
|
| DCC4796 | Smcy 5.5 | Fluorogenic fluorescent probe for imaging lipid droplets; suitable for use with two-photon microscopy |
|
| DCC4797 | Smdc818909 | Novel Allosteric Inhibitor of p97 |
|
| DCC4798 | Smer10 | Novel enhancer of the clearance of mutant aggregate-prone proteins by autophagy in mammalian cell models of Huntington's and Parkinson's disease, independent of rapamycin |
|
| DCC4799 | S-mgb-234 Bis-tfa Salt | Novel strathclyde minor groove binder (S-MGB), curing animal African trypanosomiasis (AAT) |
|
| DCC4800 | smip001 | Novel enhancer of the cyclin-dependent kinase (CDK) inhibitor p27(Kip) |
|
| DCC4801 | Smip2.1 | Novel TLR2 agonist, promoting cross-presentation by mouse and human antigen presenting cells |
|
| DCC4802 | Smk-17 | Novel highly hydrophilic and non-ATP-competitive MEK1/2 inhibitor |
|
| DCC4803 | Sml-10-70-1 | Selective, direct-acting covalent inhibitor of the K-Ras G12C mutant relative to wild-type Ras |
|
| DCC4804 | Sml-8-73-1 | Novel Active Site Inhibitor of Oncogenic K-Ras G12C |
|
| DCC4805 | Smn2-stablizer-27 | Novel Stablizer of Survival of Motor Neuron 2 (SMN2) , Post-Translationally Stablizing SMN Protein for the Treatment of Spinal Muscular Atrophy (SMA) |
|
| DCC4806 | Smn-c5 | Novel specific splicing enhancer, targeting RNA for a specific splicing correction, recognizing the interface between U1 snRNP and the SMN2 E7 5ʹ SS, promoting the U1-C zinc finger RNA duplex binding activity |
|
| DCC4807 | Smt022357 | Second-generation modulator of utrophin, increasing utrophin expression in skeletal, respiratory and cardiac muscles |
|
| DCC4808 | Smtp-7 | Novel dual inhibitor of thrombolysis and soluble epoxide hydrolase |
|
