| DC23489 |
Alizapride hydrochloride |
Alizapride (MS 5080) is a dopamine D2 antagonist with prokinetic and antiemetic effects used in the treatment of nausea and vomiting.. |
|
| DC23092 |
Alizarin |
Alizarin has a selective and effective inhibitory activity towards cancerous cells, it acts through the inhibition of ERK phosphorylation and cell cycle arrest in the S-phase. |
|
| DC9338 |
ALK inhibitor 1
Featured
|
ALK inhibitor 1 is a novel and selective inhibitor for the ALK kinase. |
|
| DC9339 |
ALK inhibitor 2
Featured
|
ALK inhibitor 2 is a novel and selective inhibitor for the ALK kinase. |
|
| DC10582 |
Diroximel Fumarete(ALKS-8700)
Featured
|
ALKS-8700 also known as diroximel fumarate, is a prodrug of monomethyl fumarate in a controlled-release formulation that rapidly and efficiently converts to MMF in the body. |
|
| DC21668 |
ALLO-2
Featured
|
ALLO-2 is a potent small molecule Smoothened (Smo) antagonist that inhibits Smo agonist Hh-Ag1.5-induced luciferase expression in TM3-Gli-Luc cells with IC50 of 6 nM. |
|
| DC12226 |
Alloepipregnanolone |
Alloepipregnanolone, a pregnane with anesthetic, hypnotic, and sedative properties, interferes with the development of rapid tolerance to the anxiolytic effect of ethanol. |
|
| DC8945 |
Allopurinol |
Allopurinol (Zyloprim) is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM. |
|
| DCAPI1097 |
Allopurinol Sodium (Aloprim)
Featured
|
Allopurinol sodium is a potent xanthine oxidase inhibitor (IC50 values of 0.2 to 50 μM). Allopurinol sodium can be used for the research of hyperuricemia and gout. Antileishmanial effect[1][2]. |
|
| DC20171 |
Alloxazine;Isoalloxazine |
Alloxazine is an A2 receptor antagonist, which is approximately 10-fold more selective for the A2B receptor than for the A2A receptor. |
|
| DC12060 |
all-trans-4-Oxoretinoic acid |
all-trans-4-Oxoretinoic acid, an active metabolite of vitamin A, induces gene transcription via binding to nuclear retinoic acid receptors (RARs). |
|
| DCAPI1478 |
Almotriptan |
Almotriptan |
|
| DCAPI1579 |
Alogliptin |
Alogliptin |
|
| DC5076 |
Alogliptin Benzoate
Featured
|
Alogliptin is an orally administered, anti-diabetic drug in the DPP-4 inhibitor class. A randomized clinical trial reporting in 2011 aimed to determine the efficacy and safety of alogliptin versus placebo and voglibose among newly diagnosed Type 2 diabete |
|
| DC10735 |
Alovudine
Featured
|
Alovudine is a DNA polymerase subunit gamma-1 (POLG) inhibitor, shows promise for treating AML. |
|
| DC9920 |
alpha-Hederin
Featured
|
alpha-hederin is a water-soluble pentacyclic triterpenoid saponin, possessing several biological properties such as antispasmodic, moliscicidic, anthelmithic and inhibiting cell proliferation. |
|
| DC23079 |
α-mangostin
Featured
|
Alpha-Mangostin has neuroprotective, anti-cancer, antifungal, neuroprotective, renoprotective, antioxidant and anti-inflammatory activities. |
|
| DC20940 |
Alprazolam |
Alprazolam (D-65MT, U 31889) is a triazolobenzodiazepine agent with anxiolytic, sedative-hypnotic and anticonvulsant activities. |
|
| DC26001 |
Alprenolol
Featured
|
Alprenolol is a non-selective beta blocker as well as 5-HT1A receptor antagonist. |
|
| DCAPI1328 |
Alprostadil(Caverject)
Featured
|
Alprostadil(Caverject) is a prostanoid receptor ligand, with Kis of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3, EP4, EP2, IP and EP1, respectively. Prostaglandin E1 induces vasodilation and inhibits platelet aggregation. Prostaglandin E1 can be used as a vasodilator for the research of peripheral vascular diseases. |
|
| DC12656 |
Alrestatin
Featured
|
Alrestatin is an AKR (aldose reductase) inhibitor, which attaches molecules to the active site of the NADP+/enzyme complex in a stacked formation. |
|
| DC8366 |
ALS22335
Featured
|
ALS-22335 is an anti-virus compound. |
|
| DC23098 |
ALS-8112 |
ALS-8112 is a potent, selective RSV polymerase inhibitor, the 5'-triphosphate of ALS-8112 (ALS-8112-TP) inhibits RSV polymerase(IC50=20 nM) without appreciable inhibition of human DNA and RNA polymerases. |
|
| DC23144 |
ALS-8176 |
ALS-8176 (Lumicitabine) is the 3',5'-di-O-isobutyryl prodrug of ALS-8112 5'-triphosphate (ALS-8112-TP), which is a potent, selective RSV polymerase inhibitor with IC50 of 20 nM. |
|
| DCAPI1290 |
Altretamine (Hexalen) |
Altretamine (Hexalen) |
|
| DC7079 |
Alvelestat (AZD9668)
Featured
|
Alvelestat (AZD9668) is a novel, oral inhibitor of neutrophil elastase (NE) with the pIC50 of 7.9 for Human NE. |
|
| DCAPI1250 |
Alverine Citrate |
Alverine citrate is a drug used for functional gastrointestinal disorders. |
|
| DC23849 |
ALW-II-49-7 |
ALW-II-49-7 (DDR2-IN-1) is a potent, selective DDR2 inhibitor with IC50 of 18.6 nM, also shows ability to inhibit DDR1 and Ephrin-family kinases (IC50=40 nM for EphB2). |
|
| DC23604 |
ALX-5407 hydrochloride
Featured
|
ALX-5407 is a potent, selective, orally active inhibitor of GlyT1 glycine transporter with IC50 of 3 nM. |
|
| DC11301 |
ALZ-801
Featured
|
ALZ-801 is a potent and orally available small-molecule β-amyloid (Aβ) anti-oligomer and aggregation inhibitor, valine-conjugated prodrug of Tramiprosate with substantially improved PK properties and gastrointestinal tolerability compared with the parent compound. ALZ-801 is an advanced and markedly improved candidate for the treatment of alzheimer’s disease. |
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