Cat. No. | Product name | CAS No. |
DC46425 |
BRD-8000.3
BRD-8000.3, as a specific EfpA inhibitor, is a narrow-spectrum, bactericidal antimycobacterial agent with good wild-type activity. BRD-8000.3 can be used for the research of tuberculosis. |
2365504-95-4 |
DC46471 |
RP101988
Featured
RP101988, the major active metabolite of Ozanimod, is a selective, potent S1PR1 (sphingosine-1-phosphate receptor 1) agonist, with EC50s of 0.19 nM and 32.8 nM for S1PR1 and S1PR5, respectivlely. |
|
DC46489 |
FATP1-IN-2
FATP1-IN-2, as an arylpiperazine derivative, is an orally active fatty acid transport protein 1 (FATP1) inhibitor (human IC50=0.43 μM, mouse IC50=0.39 μM). |
2650944-83-3 |
DC46494 |
TAK-683 TFA
TAK-683 TFA is a potent full KISS1 receptor (KISS1R) agonist (IC50=170 pM) with improved metabolic stability. TAK-683 TFA is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC50 values of 0.96 nM and 1.6 nM for human and rat, respectively. TAK-683 TFA depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer. |
|
DC46511 |
myo-Inositol trispyrophosphate hexasodium
myo-Inositol trispyrophosphate (ITPP) hexasodium, a modifier of haemoglobin, is an allosteric effector that reduces the oxygen‐binding affinity of haemoglobin and facilitates the release of oxygen by red blood cells. myo-Inositol trispyrophosphate can reverse hypoxia, control tumor growth and improve chemotherapy response. |
23103-35-7 |
DC46512 |
Rutin trihydrate
Rutin (Rutoside) trihydrate is a multifunctional natural flavonoid glycoside. Rutin trihydrate has been demonstrating excellent antioxidant, anti-inflammatory, anti-diabetic, and anti-carcinogenic properties. Cardioprotective and neuroprotective activities . |
250249-75-3 |
DC46513 |
Visnagin
Visnagin, an antioxidant furanocoumarin derivative, possess anti-inflammatory and analgesic properties. Visnagin has substantial potential to prevent Cerulein induced acute pancreatitis (AP). Visnagin possess promising vasodilator effects in vascular smooth muscles. |
82-57-5 |
DC46514 |
Cinnamtannin A2
Cinnamtannin A2, a tetrameric procyanidin, can increases GLP-1 and insulin secretion in mice. Cinnamtannin A2 could upregulate the expression of corticotrophin releasing hormone. Cinnamtannin A2 exhibits antioxidant, anti-diabetic and nephroprotective effect. |
86631-38-1 |
DC46523 |
D-JBD19 TFA
D-JBD19 TFA is a non-permeable peptide. D-JBD19 TFA has neuroprotective effects. |
|
DC46524 |
HAIYPRH hydrochloride
Featured
HAIYPRH hydrochloride, a targeting ligand, can specially bind to transferrin receptor (TfR). HAIYPRH hydrochloride can mediate the transport of nanocarriers across the blood-brain barrier. |
268215-17-4 |
DC46533 |
TCS 184 TFA
TCS 184 TFA is a polypeptide fragment. |
|
DC46534 |
(R)-Q-VD-OPh
(R)-Q-VD-OPh ((R)-QVD-OPH) is the less active enantiomer of Q-VD-OPha. Q-VD-OPha is an irreversible pan-caspase inhibitor with potent antiapoptotic properties. |
|
DC46535 |
THK-5475(THK 5475)
Featured
THK-5475(THK5475) is a precursor of THK-5470, a monoamine oxidase-B(MAO-B) imaging probe, could be used for neurological diseases study (from patent EP2019-846498). |
2410554-19-5 |
DC46536 |
Ammonium sulphate,≥99.0%,AR
Ammonium sulphate,≥99.0%,AR is an inorganic sulfate salt used for molecular biology. |
7783-20-2 |
DC46537 |
I-bu-rG Phosphoramidite
I-bu-rG Phosphoramidite is a phosphinamide monomer which can be used in the synthesis of nucleotides and nucleic acids. |
147201-04-5 |
DC46546 |
8-(3-Ethoxy-2-hydroxy-3-methylbutyloxy)psoralen
8-(3-Ethoxy-2-hydroxy-3-methylbutyloxy)psoralen is a coumarin that can be found in Heracleum pyrenaicum Lam. |
55481-87-3 |
DC46549 |
A-71915 TFA
A-71915 (TFA) is a selective inhibitor of ANP receptor (atrial natriuretic peptide-receptor), induces apoptosis and decreases insulin secretion in RINm5F pancreatic β-cells. |
|
DC46550 |
BDC2.5 mimotope 1040-31 TFA
BDC2.5 mimotope 1040-31 TFA, a BDC2.5 TCR reactive peptide, is a strong agonistic peptide for diabetogenic T cell clone BDC2.5, and the 1040-31 peptide is specific for BDC 2.5 TCR Tg+ T cells. |
|
DC46551 |
BMf-BH3
BMf-BH3 belongs to the Bcl-2 apoptosis mediator family. BH3-only protein, Bmf is a key molecule for histone deacetylase (HDAC) inhibitors mediated enhancing effect on ionizing radiation-induced cell death. |
|
DC46552 |
GRK2i TFA
GRK2i TFA is a GRK2 inhibitory polypeptide that specifically inhibitsGβγ activation of GRK2. GRK2i TFA corresponds to the Gβγ-binding domain and acts as a cellular Gβγ antagonist. |
|
DC46553 |
Nuclear pore complex protein Nup98 (315-360)
Nuclear pore complex protein Nup98 (315-360) is the 315-360 fragment part of the nuclear pore complex (NPC) protein. |
|
DC46554 |
sgp91 ds-tat Peptide 2, scrambled
sgp91 ds-tat Peptide 2, scrambled is a scrambled sequence of NADPH oxidase inhibitor gp91 ds-tat peptide. |
|
DC46555 |
SNAP-25 (187-203)
SNAP-25 (187-203), a peptide corresponding to residues 187–203 of SNAP-25, is a substrate for botulinum neurotoxin (BoNT)/A and can be used as a substrate for quantifying the activity of BoNT/C1(1-430) . |
|
DC46560 |
Cy3-N3
Cy3-N3 is a Cy3-azide fluorescent dye used to label for protein and nucleic acid. |
|
DC46561 |
Cy5-SH
Cy5-SH is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. |
|
DC46562 |
D-Ala-Lys-AMCA TFA
D-Ala-Lys-AMCA TFA is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA TFA may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. |
|
DC46569 |
hDDAH-1-IN-2 sulfate
hDDAH-1-IN-2 is a selective, orally active human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1) inhibitor. hDDAH-1-IN-2 reveals an excellent profile regarding cell toxicity/viability. |
|
DC46570 |
Serum CG probe 1
Serum CG probe 1 (formula (9)) is a compound for determining serum cholyglycine. |
|
DC46571 |
Serum CG probe 2
Serum CG probe 2 (formula (15)) is a compound for determining serum cholyglycine. |
|
DC46572 |
TL13-68
TL13-68 is a biotin-tagged version of SM1-71, and it can be used to research the mechanism of SM1-71. |
|
DC46581 |
TBI-223
TBI-223 is an orally bioavailable oxazolidinone antibiotic and an antimicrobial. TBI-223 shows activity against Mycobacterium tuberculosis (Mtb). |
2071265-08-0 |
DC46582 |
Dimethyl Citric acid
Dimethylurea/citric acid is a highly efficient deep eutectic solvent (DES). Dimethylurea/citric acid can be used as a catalyst and a green reaction medium for the synthesis of bis(indolyl)methanes, quinolines and aryl-4, 5-diphenyl-1H-imidazoles. |
53798-97-3 |
DC46584 |
MBD
MBD (7-(p-Methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole), a new fluorescent probe for protein and nucleoprotein conformation, is applied to bacterial ribosomes and to bovine trypsinogen and trypsin. MBD is strongly fluorescent upon binding to a hydrophobic area of a macromolecule. |
33984-50-8 |
DC46595 |
BigLEN(mouse) TFA
BigLEN(mouse) TFA is a GPR171 agonist. BigLEN(mouse) TFA is a proSAAS-derived neuropeptide. BigLEN(mouse) TFA regulates food intake in mice. BigLEN(mouse) inhibits the release of glutamate onto parvocellular neurons of the paraventricular nucleus in a process dependent upon activation of postsynaptic G proteins. |
|
DC46596 |
ELA-11(human) TFA
ELA-11(human) TFA is a high affinity apelin receptor agonist (Ki=14 nM). ELA-11(human) TFA is a bioactive fragment of ELA-32. ELA-11(human) TFA inhibits forskolin-induced cAMP production and stimulates β-arrestin recruitment in vitro. |
|
DC46597 |
ELA-32(human) TFA
ELA-32(human) TFA is a potent, high affinity apelin receptor agonist (IC50=0.27 nM; Kd=0.51 nM). ELA-32(human) TFA exhibits no binding GPR15 and GPR25. ELA-32(human) TFA activates the PI3K/AKT pathway and promotes self-renewal of hESCs via cell-cycle progression and protein translation. ELA-32(human) TFA also potentiates the TGFβ pathway, priming hESCs toward the endoderm lineage. ELA-32(human) TFA stimulates angiogenesis in HUVEC cells. |
|
DC46598 |
Obestatin(human) TFA
Obestatin(human) TFA is an endogenous peptide derived from the same prepropeptide as ghrelin. Obestatin(human) suppresses food intake and reduce body weight-gain in rats. |
|
DC46600 |
CY7-N3
CY7-N3 (Sulfo-Cyanine7-N3) is a water-soluble NIR dye azide for Click Chemistry. |
|
DC46601 |
Cy7-YNE
Cy7-YNE is a fluorescence labeling agent (Ex=700-770 nm,Em=790 nm). Cyanine dyes are used to label proteins, antibodies, and peptides. |
|
DC46602 |
GA-PEG5-bromide
GA-PEG5-bromide is a probe used for molecular labeling. |
|
DC46603 |
Methylamino-PEG3-benzyl
Methylamino-PEG3-benzyl is an amino PEG linker. |
|
DC46606 |
H-Ala-Ala-Tyr-OH TFA
H-Ala-Ala-Tyr-OH TFA can be synthesized mutant peptides. |
|
DC46610 |
Bacterial Sortase Substrate III, Abz/DNP
Bacterial Sortase Substrate III, Abz/DNP is an internally quenched fluorescent peptide substrate. Staphylococcus aureus transpeptidase sortase A (SrtA) reacts with its native substrate Bacterial Sortase Substrate III, Abz/DNP, cleaving it and catalyzing the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Cleavage of this substrate can be monitored at Ex/Em=320 nm/420 nm. |
|
DC46611 |
HIF-1 alpha (556-574) (TFA)
HIF-1 alpha (556-574) TFA is a short hypoxia-inducible factor-1 (HIF-1) 19 residues fragment. HIF-1 functions as master regulator of response to oxygen homeostasis. |
|
DC46612 |
InsB (9-23)
InsB (9-23) is an insulin B-chain peptide that binds to a class II histocompatibility complex (MHC) allele called I-Ag7. InsB (9-23) can be used to treat a number of autoimmune related diseases like Type 1 diabetes. |
|
DC46613 |
Interphotoreceptor retinoid-binding protein(668-687) TFA
Interphotoreceptor retinoid-binding protein(668-687) TFA, the amino acid residues 668 to 687 of human interphotoreceptor retinoid binding protein (IRBP), induces uveitis. |
|
DC46614 |
PSMα3 TFA
PSMα3 TFA is a peptide for manipulating DCs to become tolerogenic for DC vaccination strategies. PSMα3 TFA penetrates and modulates human monocyte-derived DCs by altering the TLR2- or TLR4-induced maturation, inhibiting pro- and anti-inflammatory cytokine production and reducing antigen uptake. PSMα3 TFA is an important toxin released by the most virulent strains of methicillin-resistant Staphylococcus aureus (MRSA). |
|
DC46615 |
Potassium acetate
Potassium acetate is a potassium salt employed to replenish electrolytes, for restoration of water-electrolyte balance. Potassium acetate can employ in DNA and protein purification. Potassium acetate has been used to prepare neutralizing solution for alkaline lysis of bacteria. |
127-08-2 |
DC46617 |
Lyciumin B
Lyciumin B is a cyclic peptide isolated from Lysium chinense. |
125756-66-3 |
DC46619 |
1-Methoxycarbonyl-β-carboline
1-Methoxycarbonyl-β-carboline is a natural alkaloid. |
3464-66-2 |
DC46620 |
Erucifoline
Erucifoline is a pyrrolizidine alkaloid that can be found in the aerial parts of Senecio aquaticus. |
40158-95-0 |
DC46621 |
Jacobine N-oxide
Jacobine N-oxide, an N-oxide of Jacobine which is a pyrrolizidine alkaloid, can be found in Senecio hybrids that has thrips resistance. |
38710-25-7 |
DC46622 |
Lycopsamine N-oxide
Lycopsamine N-oxide, an N-oxide of Lycopsamine which is a pyrrolizidine alkaloid, can be found in honey and bee pollen. |
95462-15-0 |
DC46637 |
Kaempferol 3-O-(2′′-O-α-rhamnosyl-6′′-O-malonyl-β-glucoside)
Kaempferol 3-O-(2′′-O-α-rhamnosyl-6′′-O-malonyl-β-glucoside) is a flavonoid glycoside compound. |
528606-92-0 |
DC46638 |
Ophiopogonanone A
Ophiopogonanone A is a homoisoflavonoidal compound isolated as a constitutent of Ophiopogonis tuber. |
75239-63-3 |
DC46641 |
Methyl tridecanoate
Methyl tridecanoate moderately inhibits β-amyloid aggregation. Methyl tridecanoate weakly inhibits acetylcholinesterase (AChE). |
1731-88-0 |
DC46642 |
Cyclamic acid sodium
Cyclamic acid (Cyclohexylsulfamic acid) sodium is one of the most widely used artificial sweetenersin food and pharmaceuticals. |
139-05-9 |
DC46643 |
DOTA-tri(t-butyl ester)
DOTA-tri(t-butyl ester) can be used in the synthesis of generations 3 (G3) nanoglobular magnetic resonance imaging (MRI) contrast agents for MR angiography and tumor angiogenesis imaging. |
137076-54-1 |
DC46644 |
Gosferol
Gosferol is a furocoumarin from the roots of Prangos ferulacea. |
37551-62-5 |
DC46645 |
Methyl heptadecanoate
Methyl heptadecanoate is a fatty acid methyl ester. |
1731-92-6 |
DC46646 |
Methyl laurate
Methyl laurate, a 12-carbon saturated fatty acid, is an esterified version of lauric acid. |
111-82-0 |
DC46647 |
Methyl myristate
Methyl myristate is a saturated fatty acid methyl ester obtained from the esterification of myristic acid. Methyl myristate shows a high melanin induction in B16F10 melanoma. |
124-10-7 |
DC46648 |
Methyl N-methylanthranilate
Methyl N-methylanthranilate, a terpene, is a pungent compound that can be found in Citrus reticulate Blanco leaves. Methyl N-methylanthranilate has the potential for pain research. |
85-91-6 |
DC46649 |
Methyl octanoate
Methyl octanoate, a volatile compound, is an aroma component persimmon wine. |
111-11-5 |
DC46650 |
Methyl undecanoate
Methyl undecanoate is an internal standard in gas-liquid chromatogram. |
1731-86-8 |
DC46651 |
NHS-Modified MMAF
NHS-Modified MMAF (WO2012143499A2, intermediat 210) is an intermediate which can be used for producing the anti-mesothelin binder-drug conjugates (ADCs). |
1404073-10-4 |
DC46652 |
Perilla ketone
Perilla ketone is a naturally occurring xenobiotic compound. Perilla ketone is activated by pulmonary P450 cytochrome enzymes in the lung, resulting in severe pulmonary damage and development of diffuse pulmonary edema. |
553-84-4 |
DC46653 |
Pyrrole-2-carboxaldehyde
Pyrrole-2-carboxaldehyde has vibrational and electronic characteristics used to establish the existence of dimeric form in solid phase and monomeric form in solution phase. |
1003-29-8 |
DC46654 |
Rutaevin 7-acetate
Rutaevin 7-acetate, a limonoid, has the potential for the research of the growth of estrogen receptor-negative and -positive human breast cancer cells. |
62306-81-4 |
DC46655 |
Tropone
Tropone is a building block in the chemical synthesis. |
539-80-0 |
DC46656 |
β-Cyclogeraniol
β-Cyclogeraniol is a natural odour compound. |
472-20-8 |
DC46657 |
ω-Pentadecalactone
ω-Pentadecalactone is a fragrance ingredient. ω-Pentadecalactone is a member of the fragrance structural group macrocyclic lactone and lactide derivative. |
106-02-5 |
DC46658 |
Methyl isovanillate
Methyl isovanillate is a secondary metabolite isolated from Vitex agnus-castus. |
6702-50-7 |
DC46659 |
(+)-Saxalin
(+)-Saxalin is a furanocoumarin that can be found in Harbouria trachypleura. |
125517-45-5 |
DC46661 |
Erlose
Erlose, a trisaccharide consisting of sucrose in soybean aphid honeydew, is utilized as a substitute sweetener preventing dental caries caused by oral flora, mainly Streptococcus mutans. Erlose may be used as a reference compound in HPLC assays that analyze the sugars of foods. |
13101-54-7 |
DC46662 |
16R-Hydroxy-3-oxolanosta7,9(11),24-trien-21-oic acid
16R-Hydroxy-3-oxolanosta7,9(11),24-trien-21-oic acid is a lanostanoid that can be found in the Sri Lankan basidiomycete Ganoderma applanatum. |
862109-64-6 |
DC46663 |
Poricoic acid BM
Poricoic acid BM is a lanostane triterpenoid that can be found in from peels of the mushroom Wolfiporia cocos. |
1815623-74-5 |
DC46664 |
DMT-dA(PAc) Phosphoramidite
DMT-dA(PAc) Phosphoramidite is a dIPhosphoramidite and can be used for DNA or RNA synthesis. |
110543-74-3 |
DC46665 |
Ro-0335
RO-0335 is a novel and potent diphenylether nonnucleoside reverse transcriptase inhibitor(NNRTI). RO-0335 inhibits Wt HIV-1 with an IC50 of 1.1 nM and retained activity (IC50< 100 nM) against 92% of a large number of NNRTI-resistant clinical isolates. |
867365-76-2 |
DC46686 |
(R)-Pirtobrutinib
Featured
(R)-Pirtobrutinib ((R)-LOXO-305) is a less active enantiomer of Pirtobrutinib. Pirtobrutinib (LOXO-305), a highly selective and non-covalent next generation BTK inhibitor, inhibits diverse BTK C481 substitution mutations. |
2101700-14-3 |
DC46696 |
RN-1747
RN-1747 is a selective TRPV4 agonist with EC50s of 0.77 μM, 4.0 μM and 4.1 μM for hTRPV4, mTRPV4 and rTRPV4, respectively. RN-1747 also antagonizes TRPM8 with IC50 of 4 μM. |
1024448-59-6 |
DC46697 |
Tertiapin-Q
Tertiapin-Q (TPNQ) is a derivative of tertiapin and inhibits BK-type K+ channels in a use- and concentration-dependent manner. Tertiapin-Q also binds to ROMK1 (Kir1.1) and GIRK1/4 (Kir3.1/3.4) channels with Ki values of 1.3 nM and 13.3 nM respectively. |
910044-56-3 |
DC46881 |
Fosdenopterin
Fosdenopterin (Precursor Z) is a synthetic cyclic pyranopterin monophosphate (cPMP). Fosdenopterin can be used for the research of molybdenum cofactor deficiency (MoCD) type A. |
150829-29-1 |
DC46882 |
Lomardexamfetamine
Lomardexamfetamine (KP 106) is an orally active central nervous system stimulant composed of d-amphetamine and a ligand. Lomardexamfetamine can be used for the research of attention-deficit hyperactivity disorder. |
1032291-80-7 |
DC46883 |
Tinlarebant
Featured
Tinlarebant (LBS-008) is an orally active non-retinoid RBP4 (retinol-binding protein 4) antagonist. Tinlarebant can be used for the research of the Stargardt disease. |
1821327-95-0 |
DC46884 |
UBE2T/FANCL-IN-1
UBE2T/FANCL-IN-1 is a potent inhibitor of UBE2T/FANCL-mediated FANCD2 monoubiquitylation that sensitizes cells to the DNA cross-linking agent, Carboplatin. |
1359415-02-3 |
DC46885 |
Mivorilaner
Mivorilaner, an antineoplastic, can be used for the research of veterinary medicine (WO2012155676,Example 245). |
1414642-93-5 |
DC46886 |
4-Nitrophenyl Laurate
4-Nitrophenyl Laurate is a class of 4-nitrophenyl ester, which can be used as enzyme substrate. |
1956-11-2 |
DC46887 |
CID1231538
Featured
CID1231538, a benzothiazole analogue, is a potent GPR35 antagonist (IC50=0.55 μM). GPR35 is a G protein-coupled receptor (GPCR). |
354126-20-8 |
DC46888 |
ACT-373898
ACT-373898 is an inactive carboxylic acid metabolite of Macitentan. Macitentan is an orally active, non-peptide dual ETA and ETB (endothelin receptor) antagonist. |
1433875-14-9 |
DC46889 |
FP-Biotin
FP-biotin is a potent organophosphorus toxicant, well-suited for searching for new biomarkers of organophosphorus toxicants exposure. FP-Biotin quantifies FAAH, ABHD6, and MAG-lipase activity. FP-biotin is used for studies with plasma because biotinylated peptides are readily purified by binding to immobilized avidin beads. |
259270-28-5 |
DC46890 |
2-Deoxy-D-glucose 6-phosphate
2-Deoxy-D-glucose 6-phosphate is an intermediate of 2-deoxy-D-glucose (2-DG) . 2-Deoxy-D-glucose is incorporated into glycogen. |
3573-50-0 |
DC46891 |
[18F]AZD4694 Precursor
[18F]AZD4694 Precursor is the precursor of [18F] AZD4694 for the synthesis of [18F] AZD4694, an amyloid-β imaging ligand with high affinity for amyloid-β plaques. |
1211333-20-8 |
DC46892 |
D-Erythritol 4-phosphate
D-erythritol 4-phosphate is a phosphorylated component isolated from the hydrolysate. |
7183-41-7 |
DC46893 |
Triton X-45(n=4)
Triton X-45 (n=4), a nonionic surfactant with a low hydrophile-lypophile balance (HLB) value and dispersible in aqueous solution at room temperature, has a Krafft point above the room temperature. Triton X-45 has the potential for the research of the hepatitis C virus (HCV). |
2315-63-1 |
DC46894 |
(S)-ATPO
(S)-ATPO is the (S)-enantiomer of ATPO, which is a competitive antagonist at GluR1-4 (AMPA-preferring) receptors. |
252930-37-3 |
DC46895 |
(R)-eIF4A3-IN-2
(R)-eIF4A3-IN-2 is a less active enantiomer of eIF4A3-IN-2. eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 (eIF4A3) inhibitor with an IC50 of 110 nM. |
2095484-82-3 |
DC46896 |
Biotin-NH-PSMA-617
Biotin-NH-PSMA-617 is a biotin-tagged PSMA-617. PSMA-617 is a small molecule targeting the prostate-specific membrane antigen (PSMA), which is directly expressed by the tumor cells . |
|
DC46897 |
Omzotirome
Omzotirome (TRC150094), a functional analog of iodothyronines, can be used for the research of hyperlipidaemia (WO2008149379). |
1092551-88-6 |
DC46898 |
Nerindocianine
Nerindocianine is a fluorescent diagnostic contrast agent. Nerindocianine is highly hydrophilic and is primarily metabolized by the kidneys, allowing for a non-invasive intraoperative ureteral imaging. |
748120-01-6 |
DC46899 |
Obafistat
Obafistat is a potent aldo-keto reductase AKR1C3 inhibitor with an IC50 of 1.2 nM for human AKR1C3 (patent WO2017202817A1, example 4). |
2160582-57-8 |
DC46900 |
Utreloxastat
Featured
Utreloxastat is a compound used for the research of the disorders including α-synucleinopathies, tauopathies, Amyotrophic lateral sclerosis (ALS), traumatic brain injury, and ischemic-reperfusion related injuries (patent WO2020081879A2, example A1). |
1213269-96-5 |
DC46901 |
2-Deoxy-D-glucose 6-phosphate disodium
2-Deoxy-D-glucose 6-phosphate disodium, a derivative of 2-Deoxy-D-glucose, is produced in mammalian cells by the action of hexokinase on 2-DG. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase. |
33068-19-8 |
DC46902 |
Poly(ethylene glycol) dithiol (Mn 3400)
Poly(ethylene glycol) dithiol (Mn 3400) is a polymer and can be used as a biomaterial to prepare hydrogels. |
68865-60-1 |
DC46903 |
Cucurbit[8]uril
Cucurbit[8]uril is a potent, low toxicity and orally active supramolecular inducer of protein heterodimerization. Cucurbit[8]uril induces heterodimerization of methylviologen and naphthalene functionalized proteins. Cucurbit[8]uril can induce energy transfer . |
259886-51-6 |
DC46904 |
(R)-Fadrozole
(R)-Fadrozole ((R)-CGS 16949A; FAD286) is a potent nonsteroidal inhibitor. (R)-Fadrozole also inhibits human placental aromatase (pIC50 = 6.17) and aldosterone biosynthesis. (R)-Fadrozole reverses cardiac fibrosis in spontaneously hypertensive heart failure rats.. |
102676-87-9 |
DC46905 |
Seletracetam lithium bromide
Seletracetam (Ucb 44212) lithium bromide, an analog of the antiepileptic agent Levetiracetam, is a SV2A modulator for the research of epilepsy. |
2024584-38-9 |
DC46906 |
Odatroltide
Odatroltide, as a nanoscale P-selectin inhibitor, is a nano-delivery system of 6,7-dihydroxyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid and KPAK to target the thrombus. |
1639303-73-3 |
DC46907 |
AM-8123
AM-8123 is an orally active and potent APJ agonist. AM-8123 inhibits Forskolin-stimulated cAMP production and promotes Gα protein activation. AM-8123 can be used for the research of cardiovascular disease. |
2049973-02-4 |
DC46908 |
PSB069
PSB069 bearing a p-chlorophenylamino residue is a potent, well-tolerated and nonselective NTPDases1, 2, 3 inhibitor(Ki=16~18 μM). |
78510-31-3 |
DC46909 |
(-)-Chromanol 293B
(-)-Chromanol 293B is a potent and selective inhibitor of the slow component of delayed rectifier K+ current (IKs). (-)-Chromanol 293B can be used for the research of antiarrhythmic. |
163163-24-4 |
DC46910 |
Sebetralstat
Featured
Sebetralstat is a plasma kallikrein inhibitor (WO2016083820). Sebetralstat can be used for the research of metabolic diseases. |
1933514-13-6 |
DC46911 |
SPOP-IN-6b hydrochloride
SPOP-IN-6b hydrochloride is a potent speckle-type POZ protein (SPOP) inhibitor with an IC50 of 3.58 μM. |
2136270-68-1 |
DC46912 |
ABC-1
ABC-1 is a phosphorylated analogue and a potential antiviral agent against Newcastle disease virus (NDV). ABC-1 has potent antiviral activity. |
309735-05-5 |
DC46914 |
Q134R
Q134R, a neuroprotective hydroxyquinoline derivative that suppresses nuclear factor of activated T cell (NFAT) signaling. Q134R can across blood-brain barrier. Q134R has the potential for Alzheimer's disease (AD) and aging-related disorders research. |
2022949-46-6 |
DC46915 |
N-Desethyl Sunitinib hydrochloride
N-Desethyl Sunitinib (SU-12662) (hydrochloride) is a metabolite of sunitinib. Sunitinib is a potent, ATP-competitive VEGFR, PDGFRβ and KIT inhibitor with Ki values of 2, 9, 17, 8 and 4 nM for VEGFR -1, -2, -3, PDGFRβ and KIT, respectively. |
|
DC46916 |
2-bromo-Hexadecanoic acid
Featured
2-Bromohexadecanoic acid (2-BP, 2-bromopalmitate) is a nonmetabolisable analogue of palmitate and acts as a palmitoylation inhibitor. 2-Bromohexadecanoic acid can directly and irreversibly inhibit the palmitoyltransferase activity of all DHHC (Asp-His-His-Cys) proteins. |
18263-25-7 |
DC46917 |
[SER140]-PLP(139-151)
Featured
[SER140]-PLP(139-151) is a polypeptide fragment of the lipid protein of myelin. |
122018-58-0 |
DC46940 |
AZD4694
AZD4694, a fluorinated β-amyloid (Aβ) plaque neuroimaging PET radioligand, shows high affinity for Aβ fibrils (Kd = 2.3 nM). |
1054629-49-0 |
DC46950 |
DHODH-IN-17
DHODH-IN-17, a 2-anilino nicotinic acid, is a human DHODH inhibitor (IC50=0.40 μM). DHODH-IN-17 can be used for theresearch of acute myeloid leukemia (AML). |
16344-26-6 |
DC46964 |
ASP-4058 hydrochloride
ASP-4058 hydrochloride is a next-generation, selective and orally active agonist for Sphingosine 1-Phosphate receptors 1 and 5 (S1P1 and S1P5), ameliorates rodent experimental autoimmune encephalomyelitis with a favorable safety profile. |
952510-14-4 |
DC46965 |
Tri-GalNAc-COOH
Featured
tri-GalNAc-COOH is an asialoglycoprotein receptor (ASGPR) ligand that can be used for LYsosome TArgeting Chimera (LYTAC) research. |
1953146-81-0 |
DC46971 |
PCSK9 degrader 1
PCSK9 degrader 1 is a selective proprotein convertase substilisin-like/kexin type 9 (PCSK9) degrader. PCSK9 degrader 1 does not affect PCSK9 function. |
2215931-60-3 |
DC46973 |
Dextromilnacipran
Dextromilnacipran (F2696; (1R,2S)-milnacipran), an enantiomer of milnacipran, is a selective serotonin and norepinephrine (5-HT/NE) reuptake inhibitor. Dextromilnacipran also is a human alpha-adrenergic receptor antagonist, with an IC50 of 3.4 μM. (patent WO2013014263A1). |
96847-55-1 |
DC46976 |
Ganosporeric acid A
Ganosporeric acid A, a natural product, is isolated from the ether-soluble fraction of the spores of Ganoderma lucidum (Curt.: Fr.) P. Karst. Ganosporeric acid A can be used for the research of liver injury. |
135357-25-4 |
DC46977 |
Polyvinylimidazole
Polyvinylimidazole (Vimdemer) is a weak basic polyelectrolyte and has been already used as a model polyelectrolyte to study adsorption properties on various minerals. |
25232-42-2 |
DC46981 |
4-Nitroquinoline 1-oxide
4-Nitroquinoline 1-oxide (4-Nitroquinoline-N-oxide, 4-NQO, 4NQO, 4Nqo, NQO, NQNO) is a highly carcinogenic model chemical that induces mutations in bacteria, fungi, and animals through the formation of bulky purine adducts. |
56-57-5 |
DC46987 |
N-Nitroso-N-methylurea
N-Nitroso-N-methylurea (NMU, MNU, NMH, 1-Methyl-1-nitrosourea, N-Methyl-Nnitrosourea, Methylnitrosourea) is a highly reliable carcinogen, mutagen, and teratogen. |
684-93-5 |
DC46988 |
Imeglimin (EMD 387008) Hydrochloride
Imeglimin (EMD 387008, IMEG, PXL 008, RVT-1501) Hydrochloride is a new class of oral glucose-lowering agents. Imeglimin normalizes glucose tolerance and insulin sensitivity by preserving mitochondrial function from oxidative stress and favoring lipid oxidation in liver of HFHSD mice. |
775351-61-6 |
DC46990 |
JAG-1, scrambled TFA
JAG-1, scrambled (scJag-1) TFA is a scrambled sequence of JAG-1 (Jagged-1 protein). JAG-1, scrambled TFA has a random sequence of the amino acids that are the same as the active fragment. JAG-1, scrambled TFA is usually used as a negative control. |
|
DC46991 |
PKG inhibitor peptide
PKG inhibitor peptide is an ATP-competitive inhibitor of cGMP-dependent protein kinase (PKG), with a Ki of 86 μM. |
82801-73-8 |
DC46992 |
Simethicone
Simethicone (Simeticone) is a nonabsorbable, surface-active, antifoaming agent. |
8050-81-5 |
DC46993 |
Thioacetamide
Thioacetamide (TAA) is a hepatotoxin frequently used for experimental purposes which produces centrilobular necrosis after a single dose administration. |
62-55-5 |
DC46994 |
Uty HY Peptide (246-254) (TFA)
Uty HY Peptide (246-254) TFA, derived from the ubiquitously transcribed tetratricopeptide repeat gene on the Y chromosome (UTY) protein as an H-Y epitope, H-YDb, is a male-specific transplantation antigen H-Y. |
|
DC46995 |
Kisspeptin-10, rat TFA
Kisspeptin-10, rat TFA is a potent vasoconstrictor and inhibitor of angiogenesis. Kisspeptin-10, rat TFA is a ligand for the rodent kisspeptin receptor (KISS1, GPR54). Kisspeptin-10 TFA reduces Methotrexate-induced reproductive toxicity as a potential antioxidant compound. |
|
DC46997 |
Guraxetan
Guraxetan can be used for the synthesis of antineoplastic lutetium (177Lu) zadavotide Guraxetan. |
|
DC46998 |
(R)-BAY-899
(R)-BAY-899 is the R-enantiomer of BAY-899. BAY-899 is an orally active and selective luteinizing hormone receptor (LH-R) antagonist with IC50s of 185 nM and 46nM for hLH (human LH) and rLH (rat LH), respectively. |
|
DC46999 |
Sec61-IN-1
Featured
Sec61-IN-1 is a potent sec61 inhibitor (Patent WO2020176863A1, compound A317). |
2484865-42-9 |
DC47005 |
Ludaterone
Ludaterone is an antiandrogen agent, with potent antiandrogenic activity. |
124548-08-9 |
DC47007 |
3,3'-Diethyloxacarbocyanine iodide
3,3'-Diethyloxacarbocyanine iodide is a microviscosity probe for micelles and microemulsions. |
905-96-4 |
DC47010 |
Astragenol
Astragenol is an intermediate used for Astragenol derivative synthesis. Astragenol derivatives are promising anti-inflammatory agents for prostate cancer research. |
86541-79-9 |
DC47012 |
Valethamate bromide
Valethamate bromide is an ester and is a potent rapidly acting anticholinergic spasmolytic and musculotropic agent which accelerates labor by improving cervical dilation. |
90-22-2 |
DC47015 |
D-(+)-Fucose
D-(+)-Fucose is a nonmetabolizable analogue of l-arabinose. D-(+)-Fucose prevents growth of Escherichia coli B/r on a mineral salts medium plus l-arabinose by inhibiting induction of the l-arabinose operon. D-fucose is a potent inducer of beta-methylgalactoside permease (MGP). |
3615-37-0 |
DC47016 |
Yadanzioside M
Yadanzioside M is a natural compound with anti-cancer activity. |
101559-99-3 |
DC47019 |
Sucunamostat
Sucunamostat is an L-aspartic acid enteropeptidase inhibitor. |
1802888-04-5 |
DC47020 |
Sophoramine
Sophoramine ((-)-Sophoramine), an alkaloid, is a dehydro-derivative of Matrine. |
6882-66-2 |
DC47021 |
Sec61-IN-2
Sec61-IN-2 (A347) is a protein secretion inhibitor (extracted from patent WO2020176863). |
2484865-72-5 |
DC47022 |
Quercetin 3,3'-dimethyl ether
Quercetin 3,3'-dimethyl ether possesses antioxidant acticity. |
4382-17-6 |
DC47023 |
Lenalidomide-C10-OH
Lenalidomide-C10-OH (6a) is an intermediate in the synthesis of INY-03-041. |
2503018-12-8 |
DC47024 |
Ivospemin
Ivospemin is an antineoplastic spermine analog. |
748119-79-1 |
DC47026 |
4-Phenyl-7,8-dihydroxycoumarin
4-Phenyl-7,8-dihydroxycoumarin is a coumarin derivative and can be used for bronchiectasiss research. |
842-01-3 |
DC47027 |
Ezurpimtrostat
Ezurpimtrostat (compound 2-2) is used for the study of fibrosis, cancer, autophagy and cathepsins B (CTSB), L (CTSL) and D (CTSD) related diseases (extracted from patent WO2020048694 A1). |
1914148-72-3 |
DC47028 |
Sec61-IN-3
Sec61-IN-2 (A3) is a protein secretion inhibitor (extracted from patent WO2020176863). |
2484862-54-4 |
DC47047 |
Polθ-IN-1-d3
Polθ-IN-1-d3 (example 1) is a deuterated Polθ inhibitor used for cancer study (extracted from patent WO2021028670). |
2598122-35-9 |
DC47060 |
Ansofaxine
Featured
Ansofaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) used for the research of depression. |
916918-80-4 |
DC47061 |
ARN 077 (enantiomer)
ARN 077 enantiomer (19) is the less active enantiomer of ARN 077, with an IC50 of 3.53 μM for rat NAAA. |
1439366-88-7 |
DC47064 |
Hexasodium phytate
Hexasodium phytate (Phytic acid hexasodium) is a phosphorus storage compound of seeds and cereal grains. Hexasodium phytate has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Hexasodium phytate inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects. |
34367-89-0 |
DC47065 |
Idetrexed
Idetrexed is a thymidylate synthase inhibitor specifically transported into alpha-folate receptor (alpha-FR)-overexpressing tumors. BGC 945 inhibited thymidylate synthase with a Ki of 1.2 nmol/L. |
501332-69-0 |
DC47067 |
Luvadaxistat
TAK-831 is a highly selective and potent inhibitor of D-amino acid oxidase (DAAO) and can be used in studies of schizophrenia. |
1425511-32-5 |
DC47068 |
Milategrast
Milategrast is useful as cell adhesion inhibitor or cell infiltration inhibitor. Milategrast in vitro inhibites the adhesion of Jurkat cells to human fibronectin with an IC50 of <5 μM. |
859217-52-0 |
DC47069 |
Ninerafaxstat
Featured
Ninerafaxstat hifts cellular metabolism from fatty acid oxidation to glucose oxidation.Ninerafaxstat decreases fatty acid oxidation and improve overall mitochondrial respiration.Ninerafaxstat inhibit the growth and proliferation of cancer cells. |
2254741-41-6 |
DC47070 |
Polyketide synthase 13-IN-1
Polyketide synthase 13-IN-1 (compound 32) is a polyketide synthase 13 inhibitor. |
2345638-96-0 |
DC47073 |
Relzomostat
Relzomostat is a methionine aminopeptidase 2 (MetAP2) inhibitor.Relzomostat may be useful for the research of obesity, type 2 diabetes, and other obesity-associated conditions. |
2081078-92-2 |
DC47075 |
Syringetin
Syringetin, a flavonoid derivative, is associated with increased BMP-2 production. Syringetin stimulates osteoblast differentiation at various stages, from maturation to terminally differentiated osteoblasts. |
4423-37-4 |
DC47076 |
Udonitrectag
Udonitrectag (REC 0559), a low molecular weight compound that mimics NGF, aims to address the issue of NGF stability. |
1458063-04-1 |
DC47078 |
Umifoxolaner
Umifoxolaner is an anti-parasitic agent (veterinary). |
2021230-37-3 |
DC47079 |
Valiloxibic acid
Valiloxibic acid is a prodrug of γ-Hydroxybutyric acid (GHB).GHB is a naturally occurring neurotransmitter and a psychoactive drug, it acts on the GHB receptor and is a weak agonist at the GABAB receptor. |
238401-16-6 |
DC47083 |
Exaluren
Exaluren (ELX-02) is an synthetic eukaryotic ribosome-selective glycoside that induces read through of nonsense mutations, resulting in normally localized full-length functional proteins. Exaluren is used for the research of cystic fibrosis caused by nonsense mutations. |
1375073-93-0 |
DC47084 |
Abrucomstat
Featured
Abrucomstat (3-Nitroxypropanol) acts as an enzyme inhibitor to decrease ruminal methanogenesis. |
100502-66-7 |
DC47085 |
AZD-CO-Ph-PEG4-Ph-CO-AZD
AZD-CO-Ph-PEG4-Ph-CO-AZD is a bis-β-lactam linker can be used for antibody-siRNA conjugate synthesis. |
2569143-72-0 |
DC47086 |
7,3′,4′-Tri-O-methyleriodictyol
7,3′,4′-Tri-O-methyleriodictyol is a flavonoid with an antimutagenic activity. 7,3′,4′-Tri-O-methyleriodictyol inhibits the furylfuramide-induced SOS response and has potency as bioantimutagens. |
70987-96-1 |
DC47090 |
Etavopivat
Featured
Etavopivat is a potent, selective, orally bioavailable red blood cell (RBC) pyruvate kinase (PKR) activator. Etavopivat has potent antisickling effects. |
2245053-57-8 |
DC47096 |
Umckalin
Umckalin is a oxygenated coumarin from Pelargonium sidoides. |
43053-62-9 |
DC47098 |
KDM2B-IN-1
KDM2B-IN-1 is a histone demethylase (kdm2b) inhibitor and can be used for hyperproliferative diseases research. |
1965248-33-2 |
DC47103 |
SB 202474
SB 202474, a negative analog of SB203580. SB 202474, which has no ability to inhibit p38 MAPK activity and is widely used as a negative control compound in p38 MAPK studies, also suppressed melanin synthesis induction. |
172747-50-1 |
DC47104 |
1,2-Dilauroyl-sn-glycero-3-phosphocholine
1,2-Dilauroyl-sn-glycero-3-phosphocholine (DLPC) is an LRH-1 agonist ligand. 1,2-Dilauroyl-sn-glycero-3-phosphocholine is a phospholipid for biological study. |
18194-25-7 |
DC47105 |
Complanatoside B
Complanatoside B is a P. chinense Fisch flavonoid with potential anti-inflammatory effects. |
142473-99-2 |
DC47106 |
[18F]-Labeled L-dopa precursor
[18F]-Labeled L-dopa precursor is a precursor for synthesis of 18F-labeled L-dopa extracted from patent WO2014095739A1, example 8. |
1614253-58-5 |
DC47113 |
DS44960156
Featured
DS44960156 is a selective Methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) inhibitor, with IC50 values of 1.6 μM and >30 μM for MTHFD2 and MTHFD1, respectively. |
2361327-08-2 |
DC47114 |
MurA-IN-1
MurA-IN-1 (compound 1a) is a PTPRR inhibitor, with IC50 values of 0.23 μM, 0.8 μM, 0.75 μM and 0.09 μM for PTP1B, PTPN5, PTPN7 and PTPRR, respectively. (A family of human MAPK-specific protein tyrosine phosphatases) |
354815-90-0 |
DC47118 |
Polyketide synthase 13-IN-3
Polyketide synthase 13-IN-3 (compound 41) is a polyketide synthase 13 inhibitor,with a MIC of 0.0625-0.125 μg/mL against the M. tuberculosis strain H37Rv. |
2221801-50-7 |
DC47124 |
KDM2B-IN-2
KDM2B-IN-1, a potent histone demethylase (kdm2b) inhibitor with an IC50 of 0.021 μM in a KDM2B TR-FRET assay. KDM2B-IN-1 can be used for hyperproliferative diseases research. |
1965248-01-4 |
DC47137 |
Rucosopasem manganese
Rucosopasem manganese (GC4711) is a selective superoxide dismutase mimetic that converts superoxide to hydrogen peroxide. Rucosopasem manganese can be used for the research of cancer. |
2248030-85-3 |
DC47138 |
Altanserin
Altanserin can synthesize Fluorine-18 Altanserin. Fluorine-18 Altanserin binds to the brain 5HT2 receptors. |
76330-71-7 |
DC47140 |
Yadanzioside K
Yadanzioside K is a natural quassinoid glucoside found in Brucea amarissima. |
101559-98-2 |
DC47144 |
ER176
ER176 is a next generation PET radioligand for imaging 18 kDa translocator protein (TSPO), a biomarker for neuroinflammation. |
1373887-29-6 |
DC47146 |
Bicyclopyrone
Featured
Bicyclopyrone is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (Hpd). |
352010-68-5 |
DC47147 |
N-3-Oxo-octanoyl-L-homoserine lactone
N-3-Oxo-octanoyl-L-homoserine lactone, a quorum-sensing signal, is an Agrobacterium autoinducer. |
147795-39-9 |
DC47151 |
10,11-Dihydrocarbamazepine
10,11-Dihydrocarbamazepine is the active metabolite of Oxcarbazepine. 10,11-Dihydrocarbamazepine also is an intermediate. Oxcarbazepine is rapidly and almost completely converted to 10,11-Dihydrocarbamazepine with probable Anticonvulsant efficacy. |
3564-73-6 |
DC47152 |
4α-TPA
4α-TPA is an inactive form of TPA, and is used as a negative control for TPA-activated events. |
63597-44-4 |
DC47153 |
DOTA Zoledronate
DOTA Zoledronate is a next-generation agent for bone targeted radionuclide therapy for diagnosing bone metastases. |
1908409-18-6 |
DC47154 |
KMG-104
KMG-104 is a highly selective fluorescent Mg2+ probe. KMG-104 has been used widely and revealed Mg2+ mobilization in cytoplasm in various types of cells. |
852057-94-4 |
DC47158 |
C12-Ceramide
C12-Ceramide (N-Lauroyl-D-erythro-sphingosine), a naturally occurring ceramide, is formed by hydrolysis of C12 sphingomyelin. C12-Ceramide can enhance the Doxorubicin toxicity in MDA-MB-231 cells. C12-Ceramide also can be used to diagnose types A and B Niemann-Pick disease. |
74713-60-3 |
DC47162 |
10-Nitrooleic acid
10-Nitrooleic acid (CXA-10), a nitro fatty acid, has potential effects in disease states in which oxidative stress, inflammation, fibrosis, and/or direct tissue toxicity play significant roles. |
875685-46-4 |
DC47163 |
N-Palmitoyl-L-glutamine
N-Palmitoyl-L-glutamine is a Glutamine derivative. |
58725-34-1 |
DC47168 |
pyCTZ hydrochloride
pyCTZ (Pyridyl CTZ) hydrochloride, a pyridyl Coelenterazine (CTZ) analog, and is an ATP-independent pyridyl substrate of LumiLuc luciferase. pyCTZ hydrochloride generates strong blue bioluminescence in the presence of luciferases. pyCTZ hydrochloride can be used for aequorin-based calcium sensing. |
|
DC47169 |
pyCTZ TFA
pyCTZ (Pyridyl CTZ) TFA, a pyridyl Coelenterazine (CTZ) analog, and is an ATP-independent pyridyl substrate of LumiLuc luciferase. pyCTZ TFA generates strong blue bioluminescence in the presence of luciferases. pyCTZ TFA can be used for aequorin-based calcium sensing. |
|
DC47177 |
Docosahexaenoic acid ethyl ester
Docosahexaenoic acid ethyl ester (Ethyl docosahexaenoate) is a 90% concentrated ethyl ester of docosahexaenoic acid manufactured from the microalgal oil. Docosahexaenoic acid ethyl ester enhances 6-hydroxydopamine-induced neuronal damage by induction of lipid peroxidation in mouse striatum. Docosahexaenoic acid (DHA) is a key component of the cell membrane, and its peroxidation is inducible due to the double-bond chemical structure. Docosahexaenoic acid has neuroprotective effects. |
81926-94-5 |
DC47178 |
Mead acid
Mead acid (5,8,11-Eicosatrienoic acid), an unsaturated (Omega-9) fatty acid, is an indicator of essential fatty acid deficiency. |
20590-32-3 |
DC47179 |
Tyrosylleucine
Tyrosylleucine (Tyr-Leu, YL), an orally active dipeptide, exhibits a potent antidepressant-like activity. |
17355-10-1 |