Cat. No. | Product name | CAS No. |
DC22936 |
BMS-242
A potent PD-1/PD-L1 interaction inhibitor with IC50 of 6-100 nM in a homogenous time-resolved fluorescence binding assay.. |
1675204-51-9 |
DC22935 |
BMS-200
A potent PD-1/PD-L1 interaction inhibitor with IC50 of 80 nM in a homogenous time-resolved fluorescence binding assay.. |
1675203-82-3 |
DC22510 |
AN-3199
A potent PDE4 inhibitor with IC50 of 94.5 nM.. |
1187187-10-5 |
DC22850 |
Genz 669178
A potent PfDHODH inhibitor that exhibits low nanomolar in vitro potency against DHODH from P falciparum, P vivax, and P berghei. |
1254834-91-7 |
DC22976 |
PDE12-IN-3
A potent phosphodiesterase 12 (PDE12) with Ki of 17.5 nM, with no activity for related enzyme CNOT6 (Ki>10 uM). |
1803357-22-3 |
DC22588 |
PK-14105
A potent photoaffinity ligand for the peripheral-type benzodiazepine binding site with Ki of 4 nM. |
107257-28-3 |
DC25092 |
Wortmannin
Featured
A potent PI3K inhibitor with IC50 3 nM, does not inhibit PI4K activity. |
19545-26-7 |
DC23322 |
Vacuolin-1
Featured
A potent PIKfyve inhibitor that inhibits autophagy by impairing lysosomal maturation, potently and reversibly inhibits autophagosome-lysosome fusion by activating RAB5A. |
351986-85-1 |
DC25048 |
CGP-53716
A potent protein tyrosine kinase inhibitor that shows selectivity for PDGFR in vitro and in cells. |
152459-94-4 |
DC22624 |
Asenapine
A potent psychopharmacologic agent that shows high affinity for 5-HT, dopamine, histamine and adrenoceptors. |
65576-45-6 |
DC22929 |
KIN-1400
A potent RIG-I-like receptor (RLR) agonist that triggers IRF3-dependent innate immune antiviral genes and IFN-β expression. |
446826-86-4 |
DC22791 |
Kinase inhibitor C1
A potent small molecule inhibitor of MELK kinase activity with IC50 of 42 nM. |
133712-17-1 |
DC21417 |
NSC 141562
A potent small-molecule inhibitor of the MIR155 host gene/miR-155 axis. |
|
DC5132 |
Tropisetron HCL
A potent SR-3 antagonist |
105826-92-4 |
DC22530 |
WEHI-345 analog
A potent Src inhibitor extracted from patent WO/2012003544A1.. |
1354825-62-9 |
DC20416 |
Imipramine Blue
A potent STAT5 inhibitor with a dual mechanism of action, potently inhibits STAT5 through liberation of endogenous phosphatase activity following NADPH oxidase (NOX) inhibition at 200-300 nM. |
1169943-24-1 |
DC22933 |
TLR7-Agonist-31
A potent TLR7 agonist with EC50 of 59 nM.. |
1229024-57-0 |
DC22932 |
TLR7-Agonist-54
A potent TLR7 agonist with EC50 of 8.6 nM. . |
1229024-78-5 |
DC22934 |
3M-011
Featured
3M-011 is a potent TLR7/8 agonist and cytokine inducer; stimulates type I interferon (IFN) and other cytokines such as TNF-alpha, IL-12, and IFN-gamma from rat peripheral blood mononuclear cells; induces IL-12 and COX-2 expression in mDC from HIV+ and HIV- individuals, and inhibits H3N2 influenza viral replication in the nasal cavity; potentiates NK cytotoxicity, and shows antitumor effects in scid/B6 mice and scid/NOD mice. |
642473-62-9 |
DC22922 |
3M-003
A potent TLR7/8 agonist that induces robust production of the Th1-polarizing cytokines TNF-alpha and IL-12 from neonatal antigen-presenting cells (APCs).. |
162397-26-4 |
DC22393 |
IW-927
A potent TNFα/TNFRc1 interaction antagonist with IC50 of 50 nM, with no affinity for the related cytokine receptors TNFRc2 or CD40, and no cytotoxicity (>100 uM). |
389142-48-7 |
DC22618 |
MMAD hydrochloride
A potent tubulin inhibitor that is a toxin payload in antibody drug conjugates (ADCs).. |
173441-26-4 |