Cat. No. | Product name | CAS No. |
DC8378 |
Mavatrep(JNJ-39439335)
Featured
Mavatrep is an orally bioavailable TRPV1 antagonist (Ki=6.5 nM), exhibits minimal effect on the enzymatic activity (IC50 > 25 μM) of CYP isoforms 3A4, 1A2, and 2D6. |
956274-94-5 |
DC10013 |
Mirogabalin
Featured
Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium-channel complexes in the CNS. |
1138245-13-2 |
DC10532 |
Mirogabalin besylate
Featured
Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium-channel complexes in the CNS. |
1138245-21-2 |
DC11905 |
Opiranserin
Opiranserin (VVZ-149, VVZ-000149) is a potent, selective, mixed glycine GlyT2 transporter blocker (IC50= 0.86 uM), purine P2X3 receptor antagonist (IC50=0.87 uM) and serotonin 5-HT2A receptor antagonist (IC50=1.3 uM). |
1441000-45-8 |
DC10255 |
Parecoxib
Parecoxib is a selective COX2 inhibitor. |
198470-84-7 |
DCAPI1503 |
PARECOXIB SODIUM
PARECOXIB SODIUM |
198470-85-8 |
DC10529 |
PF 05089771
Featured
PF 05089771 is a Nav1.7 channel blocker extracted from patent WO/2010/079443 A1, compound example 788, has an IC50 of 8.6 nM. |
1235403-62-9 |
DC10631 |
PF-06273340
PF-06273340 is a highly potent, kinases elective, well-tolerated pan-Trk inhibitor with IC50 values of 6, 4, 3 nM for TrkA, TrkB, Trk C, respectively. |
1402438-74-7 |
DC7274 |
S1RA
Featured
S1RA(E-52862) is a potent and selective sigma-1 receptor(σ1R, Ki=17 nM), showed good selectivity against σ2R (Ki > 1000 nM). |
878141-96-9 |
DC9264 |
S1RA hydrochloride
Featured
S1RA(E-52862) is a potent and selective sigma-1 receptor(σ1R, Ki=17 nM), showed good selectivity against σ2R (Ki > 1000 nM). |
1265917-14-3 |
DC9635 |
SB-705498
Featured
SB-705498 is a potent, selective and orally bioavailable transient receptor potential vanilloid 1 (TRPV1) receptor antagonist with a pIC50 of 7.1. |
501951-42-4 |
DC10475 |
Grapiprant
Featured
Grapiprant is a selective EP4 receptor antagonist whose physiological ligand is prostaglandin E2 (PGE2) |
415903-37-6 |