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Cat. No. Product Name Field of Application Chemical Structure
DC42379 Pimelic Diphenylamide 106 (analog)
Pimelic Diphenylamide 106 analog is an analog of Pimelic Diphenylamide 106 with unknown biological activity.
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DC42378 NVP-CGM097 (stereoisomer)
NVP-CGM097 (stereoisomer) is a stereoisomer of NVP-CGM097, with no special bioactivity. NVP-CGM097 is a potent and selective MDM2.
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DC42377 S107 hydrochloride
S107 hydrochloride is a RyR-selective 1,4-benzothiazepine derivative that stabilizes RyR2 channels by enhancing the binding affinity of calstabin2 to mutant and/or PKA-phosphorylated channels.
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DC42376 Sofosbuvir impurity C
Sofosbuvir impurity C is an impurity of Sofosbuvir, Sofosbuvir is an active of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity.
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DC42375 N-Methyl pemetrexed
N-Methyl pemetrexed is an impurity of Pemetrexed. Pemetrexed is an antifolate cytotoxic agent that can be used for the research of cancer.
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DC42374 Captopril EP Impurity E
Captopril EP Impurity E is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) (IC50=0.025 μM).
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DC42373 Captopril EP Impurity C
Captopril EP Impurity C is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) (IC50=0.025 μM).
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DC42372 Captopril EP Impurity B
Captopril EP Impurity B is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) (IC50=0.025 μM).
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DC42371 5-Hydroxymethyl-2’-deoxycytidine
5-Hydroxymethyl-2’-deoxycytidine (5hmdC) is an oxidation derivative of 5-methyl-2'-deoxycytidine (5-mdC) in DNA. 5-Hydroxymethyl-2’-deoxycytidine may serve as a marker of irreversibly damaged cells.
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DC42370 5-A-RU-PABC-Val-Cit-Fmoc
5-A-RU-PABC-Val-Cit-Fmoc is the prodrug of 5-A-RU. 5-A-RU, a precursor of bacterial Riboflavin, is a mucosal-associated invariant T (MAIT) cells activator. 5-A-RU forms potent MAIT-activating antigens via non-enzymatic reactions with small molecules, such as glyoxal and methylglyoxal, which are derived from other metabolic pathways.
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DC42369 trans-Stilbene
trans-Stilbene ((E)-Stilbene) is used in the manufacturing of dye lasers, optical brighteners, non-steroidal synthetic estrogens.
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DC42368 Nazartinib S-enantiomer
Nazartinib S-enantiomer (EGF816 S-enantiomer) is the less active S-enantiomer of Nazartinib. Nazartinib (EGF816) is an EGFR.
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DC42367 PDE10-IN-1
PDE10-IN-1 is a potent PDE10-IN-1 extracted from Patent WO 2013192273 A1, for treating CNS and metabolic disorders.
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DC42366 (-)-TK216
(-)-TK216 is an enantiomer of TK216. TK216 is an orally active and potent E26 transformation specific (ETS). TK216 directly binds EWS-FLI1 and inhibits EWS-FLI1 protein interactions.
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DC42365 TH1338
TH1338 (compound 3b), an orally active camptothecin derivative and a potent chemotherapeutic agent for cancer, demonstrates excellent cytotoxic potency against human tumor cell lines in vitro. TH1338 (compound 3b) possesses significant brain penetration, favorable efflux pump properties, and hematological toxicity profile.
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DC42364 KMH-233
KMH-233, a potent, reversible and selective l-type amino acid transporter 1 (LAT1), inhibits the uptake of LAT1 substrate, l-leucin (IC50=18 μM) as well as cell growth. KMH-233 significantly potentiates the efficacy of Bestatin and Cisplatin even at low concentrations (25 μM).
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DC42363 Vinleurosine sulfate
Vinleurosine sulfate is one of four indole alkaloids with antineoplastic activity that have been isolated from the periwinkle plant (Vinca rosea Linn.).
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DC42361 1,3,6,8-Tetrahydroxynaphthalene
1,3,6,8-Tetrahydroxynaphthalene (T4HN) is an indispensable precursor to DHN (1,8-Dihydroxynaphthalene) melanin and is an unique symmetrical compound of polyketide origin.
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DC42360 Tenalisib R Enantiomer
Tenalisib R Enantiomer is an R enantiomer of Tenalisib.
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DC42359 TTA-Q6(isomer)
TTA-Q6(isomer) is an isomer of TTA-Q6. TTA-Q6 is a selective T-type Ca2+ channel antagonist.
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DC42358 NF-κΒ activator 2
NF-κΒ activator 2 is a potent and orally active NF-ҡB activator, with an EC50 of 1.58 μM. NF-κΒ activator 2 induces SOD2 through increasing NF-ҡB expression and activation. NF-κΒ activator 2 can be used for the research of amyotrophic lateral sclerosis (ALS).
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DC42355 Kurarinol
Kurarinol is a flavanone found in the root of Sophora flavescens. Kurarinol is a competitive tyrosinase, with IC50 of 0.1 μM for mushroom tyrosinase.
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DC42352 9-cis-Vitamin A palmitate
9-cis-Vitamin A palmitate (9-cis-Retinyl palmitate) is a 9-cis isomer formed by vitamin A palmitate in corn flakes. 9-cis-Vitamin A palmitate has a biological activity of 26% of all-trans-vitamin A palmitate, the most biologically ac-tive form of vitamin A.
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DC42351 13-cis-Vitamin A palmitate
13-cis-Vitamin A palmitate (13-cis-Retinyl palmitate) is a 13-cis isomer formed by vitamin A palmitate in corn flakes. 13-cis-Vitamin A palmitate has a biological activity of 75% of all-trans-vitamin A palmitate, the most biologically ac-tive form of vitamin A.
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DC42350 ATP disodium trihydrate
ATP disodium trihydrate (Adenosine 5'-triphosphate disodium trihydrate) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium trihydrate is an important endogenous signaling molecule in immunity and inflammation.
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DC42348 Dihydroxyacetone phosphate hemimagnesium hydrate
Dihydroxyacetone phosphate hemimagnesium hydrate is an important intermediate in lipid biosynthesis and in glycolysis. It is a biochemical compound involved in many metabolic pathways, including the Calvin cycle in plants and glycolysis. Dihydroxyacetone phosphate hemimagnesium hydrate is found to be associated with transaldolase deficiency, which is an inborn error of metabolism.
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DC42347 sn-Glycerol 3-phosphate lithium
sn-Glycerol 3-phosphate lithium is produced by cytosolic glycerol 3-phosphate dehydrogenase pathway through the reduction of dihydroxyacetone phosphate using NADH formed during glycolysis.
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DC42346 N-(2-Hydroxyethyl)oxamic acid
N-(2-hydroxyethyl)-oxamic acid is formed when Metronidazole is reduced either chemically or by the action of the intestinal bacteria. Metronidazole, a nitroimidazole antibiotic, has activity against various protozoans and most Gram-negative and Gram-positive anaerobic bacteria.
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DC42344 MPP+ iodide
MPP+ iodide, a toxic metabolite of the neurotoxin MPTP, causes symptom of Parkinson's disease in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ iodide is taken up by the dopamine transporter into dopaminergic neurons where it exerts its neurotoxic action on mitochondria by affecting complex I of the respiratory chain. MPP+ iodide is also a high affinity substrate for the serotonin transporter (SERT).
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DC42343 Mitochondrial respiration-IN-1 hydrobromide
Mitochondrial respiration-IN-1 hydrobromide (compound 49) is a potent mitochondrial (IC50=8.8 mg/ml) extracted from patent US20110301180A1, compound 49. Mitochondrial respiration-IN-1 hydrobromide significantly reduces mitochondrial respiration in platelets.
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