| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DCC4799 | S-mgb-234 Bis-tfa Salt | Novel strathclyde minor groove binder (S-MGB), curing animal African trypanosomiasis (AAT) |
|
| DCC4800 | smip001 | Novel enhancer of the cyclin-dependent kinase (CDK) inhibitor p27(Kip) |
|
| DCC4801 | Smip2.1 | Novel TLR2 agonist, promoting cross-presentation by mouse and human antigen presenting cells |
|
| DCC4802 | Smk-17 | Novel highly hydrophilic and non-ATP-competitive MEK1/2 inhibitor |
|
| DCC4803 | Sml-10-70-1 | Selective, direct-acting covalent inhibitor of the K-Ras G12C mutant relative to wild-type Ras |
|
| DCC4804 | Sml-8-73-1 | Novel Active Site Inhibitor of Oncogenic K-Ras G12C |
|
| DCC4805 | Smn2-stablizer-27 | Novel Stablizer of Survival of Motor Neuron 2 (SMN2) , Post-Translationally Stablizing SMN Protein for the Treatment of Spinal Muscular Atrophy (SMA) |
|
| DCC4806 | Smn-c5 | Novel specific splicing enhancer, targeting RNA for a specific splicing correction, recognizing the interface between U1 snRNP and the SMN2 E7 5ʹ SS, promoting the U1-C zinc finger RNA duplex binding activity |
|
| DCC4807 | Smt022357 | Second-generation modulator of utrophin, increasing utrophin expression in skeletal, respiratory and cardiac muscles |
|
| DCC4808 | Smtp-7 | Novel dual inhibitor of thrombolysis and soluble epoxide hydrolase |
|
| DCC4809 | Smurf1 Inhibitor 1 | Novel Smurf1 inhibitor, promoting bone formation in mouse models of distinctive age-related osteoporosis |
|
| DCC4810 | Smu-z1 Featured | Novel potent TLR1/2 Specific Agonist, Suppressing Leukemia Cancer Cell Growth by Stimulating Cytotoxic T Lymphocytes |
|
| DCC4811 | Sn16713 | Selective ligand of GC-rich sequences in DNA |
|
| DCC4812 | Sn-28049 | Novel potent DNA-binding topoisomerase II-directed antitumor agent. |
|
| DCC4813 | Sn34037 | Novel specific inhibitor of Aldo-keto reductase 1C3 (AKR1C3, EC 1.1.1.188) |
|
| DCC4814 | Sn-38 Prodrug 3c | Novel Bioorthogonal Prodrug of SN-38 with Fast Reaction Kinetics and High Releasing Efficiency In Vivo |
|
| DCC4815 | Snap-398299 | Potent and selective GAL3 antagonist |
|
| DCC4816 | Snap-5089 | Highly selective alpha1A-adrenoceptor antagonist |
|
| DCC4817 | Sniper(abl)-38 | Specific and Nongenetic IAP-dependent Protein Eraser (SNIPER), acting as a protein degradation inducer of oncogenic BCR-ABL protein |
|
| DCC4818 | Sniper(brd4)-1 | Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Eraser (SNIPER), acting as a a protein degradation inducer of bromodomain-containing protein 4 (BRD4) |
|
| DCC4819 | Sniper(ch6) | Novel fused proteins degrader of the His-tagged CRABP-II and Smad2 in cells |
|
| DCC4820 | Sniper(crabp)-11 | Novel potent degrader of the mitochondrial CRABP-II protein |
|
| DCC4821 | Sniper(er)-87 | Novel potent and selective degrader of the ERα protein |
|
| DCC4822 | Sniper(pde4)-9 | Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Eraser (SNIPER), acting as a a protein degradation inducer of phosphodiesterase-4 (PDE4) |
|
| DCC4823 | Snri-h05 | Novel potent serotonin and noradrenaline reuptake inhibitor (SNRI) with moderate 5-HT2A antagonist activity for anti-depression |
|
| DCC4824 | sns-oh | Inducer of apoptosis in neuroblastoma cells through inhibition of AKT signaling pathway |
|
| DCC4825 | Snu-bp | Novel agonist of PPAR-gamma, inhibiting lipopolysaccharide (LPS)-induced NO production and pro-inflammatory cytokines, potentiating interleukin-4-induced arginase-1 expression, promoting microglial polarization toward to an M2 anti-inflammatory phenotype |
|
| DCC4826 | Snx2-1-108 | Highly selective inhibitor of CDK8 and its isoform CDK19 |
|
| DCC4827 | So1989 | Novel macrophage modulator, inhibiting inflammation and M1 polarization of macrophages, restoring the balance between M1-polarized and M2-polarized macrophages in high fat diets (HFD)-induced obese mice resulting in the improvement of adipose inflammation |
|
| DCC4828 | soblidotin | Inhibitor of tubulin polymerization, resulting in cell cycle arrest and induction of apoptosis |
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