| DC67432 |
Acriflavinium chloride
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| DC67433 |
(1R,1'S,3'R/1R,1'R,3'S)-L-054,264
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(1R,1'S,3'R/1R,1'R,3'S)-L-054,264 is a selective non-peptide human somatostatin receptor subtype 2 (sst2) agonist. (1R,1'S,3'R/1R,1'R,3'S)-L-054,264 can be used in the study of retinal neuromodulation. |
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| DC67434 |
2-oxa-8-azabicyclo4.2.0octan-7-one
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| DC67435 |
Fluphenazine Impurity 10
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| DC67436 |
Butanoic acid, 2-[(dimethylamino)methylene]-3-oxo-, ethyl ester, (2Z)-
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| DC60822 |
JNJ-9676
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JNJ-9676 is a small-molecule inhibitor targeting the coronavirus M protein. JNJ-9676 has double-digit nanomolar in vitro potency against sarbecoviruses including SARS-CoV, all tested variants of SARS-CoV-2, and bat and pangolin SARS-like coronaviruses. |
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| DC60823 |
Ac-ATAD-AFC(Caspase-12 Substrate)
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Ac-ATAD-AFC(Caspase-12 Substrate) is a fluorogenic substrate for caspase-12. |
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| DC60824 |
Ac-LETD-AFC
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Ac-LETD-AFC is a caspase-8 fluorogenic substrate. Ac-LETD-AFC can measure caspase-8 fluorogenic activity and can be used for the research of cancer cell apoptosis and oxidative stress metabolism. |
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| DC67437 |
PI-2620 precursor
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PI-2620 precursor is the precursor of PI2620. 18F-PI-2620 is a PET tracer with high binding affinity for aggregated tau, a key pathologic feature of Alzheimer disease (AD) and other neurodegenerative disorders. |
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| DC67438 |
6-(2,6-dimethoxyphenyl)pyrido[2,3-d]pyrimidine-2,7-diamine
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| DC60825 |
11-10-8
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11-10-8 is an ionizable cationic lipid (pKa = 6.22) that has been used in the generation of lipid nanoparticles (LNPs) for mRNA delivery in vivo.1 LNPs containing 11-10-8 and encapsulating mRNA encoding the Cas9 nuclease and small-guide RNA (sgRNA) targeting transthyretin (TTR), a thyroid hormone carrier protein, decrease serum levels of TTR in mice. LNPs containing 11-10-8 and encapsulating mRNA encoding human fibroblast growth factor 21 (hFGF21) increase serum levels of hFGF21, decrease body and liver weights, and reduce the liver steatosis score in a mouse model of obesity induced by a high-fat diet. |
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| DC67440 |
SBFI-26
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SBFI-26 (SBFI26) is a selective small-molecule antagonist of FABP5 and FABP7 that enhances endogenous anandamide signaling. It exhibits dose-dependent antinociceptive effects against mechanical hyperalgesia in vivo, along with notable anti-inflammatory activity. Additionally, it inhibits castration-resistant prostate cancer progression through competitive inhibition of oncogenic FABP5. |
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| DC67441 |
Glutamate-cysteine ligase inhibitor EN25
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EN25 is a covalent allosteric inhibitor of glutamate-cysteine ligase (GCL), selectively targeting cysteine residue C114 on the GCLM regulatory subunit with an IC50 of 16 μM. |
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| DC67442 |
L-674573
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L-674573 is a quinoline-based compound that specifically blocks 5-lipoxygenase cellular translocation, thereby inhibiting leukotriene biosynthesis. |
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