| DC65943 |
Naphthol AS-BI phosphate disodium salt
Featured
|
|
|
| DC65944 |
N406211
Featured
|
|
|
| DC65945 |
Imiloxan hydrochloride
Featured
|
Imiloxan hydrochloride is a potent and selective alpha 2B-adrenoceptor antagonist. Imiloxan hydrochloride has the potential for acute kidney injury research. |
|
| DC65946 |
(R)-(-)-α-Methylhistamine dihydrobromide
Featured
|
(R)-(-)-α-Methylhistamine dihydrobromide is a potent, selective and brain-penetrant agonist of H3 histamine receptor, with a Kd of 50.3 nM. (R)-(-)-α-Methylhistamine dihydrobromide can enhance memory retention, attenuates memory impairment in rats. |
|
| DC65947 |
(S)-(+)-2-Chlorophenylglycine Methyl Ester Tartrate Salt
Featured
|
|
|
| DC65948 |
2-Chloromethyl-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine, Hydrochloride
Featured
|
|
|
| DC65949 |
2-Mercaptobenzimidazole
Featured
|
|
|
| DC65950 |
(S)-(+)-2-Chlorophenylglycine Methyl Ester
Featured
|
|
|
| DC65951 |
PTP1B-IN-4
Featured
|
PTP1B-IN-4 is a non-competitive allosteric inhibitor of the protein tyrosine phosphatase PTP1B, with an IC50 of 8 μM. PTP1B-IN-4 is potentail for the research of obesity and diabetes. |
|
| DC65952 |
10-Hydroxygeraniol
Featured
|
|
|
| DC65953 |
10-Formyl Folic Acid
Featured
|
10-Formylfolic acid is a potent inhibitor of dihydrofolate reductase. |
|
| DC65954 |
OTUB1/USP8 inhibitor 61
Featured
|
OTUB1/USP8-IN-1 is a potent dual OTUB1/USP8 inhibitor with IC50 values of 0.17 and 0.28 nM for OTUB1 and USP8, respectively. OTUB1/USP8-IN-1 can be used in research of cancer. |
|
| DC65955 |
GOSLO SR 5-69
Featured
|
GoSlo-SR-5-69 is a potent activator of large conductance Ca2+-activated K+ (BK) channels, with an EC50 of 251 nM. |
|
| DC65956 |
Dicyclopenta[b,e]pyridin-8(1H)-imine, 2,3,4,5,6,7-hexahydro-4-methyl-
Featured
|
|
|
| DC65957 |
8-Azabicyclo[3.2.1]octane-8-carboxamide, 3-(2-pyridinylsulfonyl)-N-[4-(trifluoromethyl)phenyl]-
Featured
|
|
|
| DC65958 |
3-Hydroxy-4,5-bis-benzyloxy-6-benzyloxymethyl-2-phenyl2-oxo-2λ5-[1,2]oxaphosphinane
Featured
|
|
|
| DC65959 |
Vocacapsaicin hydrochloride
Featured
|
Use of Vocacapsaicin hydrochloride
Vocacapsaicin (CA-008) hydrochloride, a prodrug of Capsaicin, is a first-in-class non-opioid TRPV1 agonist. Vocacapsaicin hydrochloride can provide meaningful and long-lasting pain relief. |
|
| DC72914 |
UE2343 |
UE2343 (UE-2343, Xanamem) is a potent, orally bioavailable, brain penetrant 11β-HSD1 inhibitor with IC50 of 24 nM in cell-free assays, with no activity for isozyme 11β-HSD2. |
|
| DC72915 |
AM4085 |
AM4085 is a potent, orally bioavailable lectin domain of FmLH antagonist with IC50 of 0.19 uM. |
|
| DC72916 |
BB2-50F |
BB2-50F is a bactericidal inhibitor of M. tuberculosis with MIC value of 8 uM (H37Rv), inhibits succinate dehydrogenase and the F1Fo-ATP synthase. |
|
| DC72917 |
BDM71339 |
BDM71339 is the first small molecule inhibitor of mycobacterial transcriptional regulator EthR, boosts ten times the activity of ethionamide in TB-infected macrophages at low nanomolar concentrations (EC50=72 nM) in vitro. |
|
| DC72918 |
BDM88855 hydrochloride |
BDM88855 Hcl is a novel allosteric efflux-pump inhibitor that potentiate antibiotic activity in E. coli through inhibition of its primary RND transporter, AcrAB-TolC. |
|
| DC72919 |
BDM91288 |
BDM91288 is a pyridylpiperazine-based AcrB efflux pump inhibitor, potentiate the activity of a panel of antibiotics against K. pneumoniae. |
|
| DC72920 |
BFA1 |
BFA1 is a specific small-molecule activator of Burkholderia FixLJ signaling pathway, inhibit the virulence of multiple pathogenic Burkholderia species. |
|
| DC72921 |
COE2-2hexyl |
COE2-2hexyl is a broad-spectrum antibacterial conjugated oligoelectrolyte (COE), does not evoke bacterial resistance, inhibits methicillin-resistant S. aureus (MRSA, MT3302) with MIC of 1 ug/mL. |
|
| DC72922 |
Cresomycin |
Cresomycin (CRM) is a bridged macrobicyclic antibiotic via inhibiting bacterial ribosome, shows broad efficacy of CRM against clinical isolates of MDR Gram-negative pathogens differentiates the synthetic macrobicyclic class from traditional lincosamides. |
|
| DC72923 |
CUO246 |
CUO246 (CUO-246) is a potent, selective bacterial DNA gyrase/topoisomerase IV inhibitor, CUO246 is active in vitro against a broad range of Gram-positive, fastidious Gram-negative, and atypical bacterial pathogens. |
|
| DC72924 |
D66 |
D66 is a specific small molecule that disrupts S. Typhimurium membrane voltage without cell lysis, prevents S. Typhimurium survival in macrophages (IC50=6.0 uM) and inhibits bacterial growth under conditions that compromise the cell envelope. |
|
| DC72925 |
DS01750413 |
DS01750413 is a novel FtsZ inhibitor and new derivative of PC190723 (Cat. PC-47012), inhibits S. aureus FtsZ protein with IC50 of 2 mg/L, has an IC50 of 0.03 mg/L in cell elongation assay of B. subtilis. |
|
| DC72926 |
EPM35 |
EPM35 (Efflux pump modulator 35) is a small molecule that bind AcrB (KD=0.29 uM), inhibit AcrAB-TolC and modulates bacterial efflux pump activity, reduces bacterial intracellular load. |
|
