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Cat. No. Product name CAS No.
DC9850 D-3263 HCl Featured

D3263 is a novel, orally bioavailable small molecule Trp-p8 agonist.

1008763-54-9
DC7011 D4476 (D-4476) Featured

D4476, a cell-permeant inhibitor of CK1δ (IC90 <10 uM), suppresses the site-specific phosphorylation and nuclear exclusion of FOXO1a, D4476 originally identified as inhibitors of activin receptor-like kinase ALK5.

301836-43-1
DC11124 D-520

D-520 is a potent, multifunctional D2/D3 agonist with Ki of 41.8 /0.35 nM, modulates aggregation of alpha-synuclein (αSN) and reduces toxicity of preformed aggregates of αSN.

1619269-47-4
DC20053 D5D-IN-326

D5D-IN-326 is a selective, orally active delta-5 desaturase (D5D) inhibitor, with IC50s of 72 and 22 nM for rat and human D5D in enzymic and cell-based assays, respectively, has no effect on D6D or D9D activity. D5D-IN-326 reduces insulin resistance and d

1236767-85-3
DC9589 D609 Featured

D609 is a selective competitive phosphatidyl choline-specific phospholipase C (PC-PLC) inhibitor (Ki = 6.4 μM); antiviral and antitumor agent.

83373-60-8
DC7393 D-64131 Featured

D-64131 is a novel inhibitor of Tubulin polymerization that competitively binds with [(3)H]colchicine to αβ-Tubulin.

74588-78-6
DC11232 D715-2441

D715-2441 (D 715-2441) is a novel antiviral compound that interferes with the conserved cap-binding domain of the PB2 protein, exhibits potent antiviral activity against influenza A viruses (IAVs) with IC50 of 1.7-4.4 uM.

54245-10-2
DC9259 DAA1106 Featured

DAA1106 is a potent and selective ligand for peripheral benzodiazepine receptors, in mitochondrial fractions of the rat brain.

220551-92-8
DC8913 Dabigatran etexilate mesylate Featured

Dabigatran etexilate mesylate (BIBR 1048MS) is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor (DTI) with Ki value of 4.5 nM.

872728-81-9
DC5149 Dabrafenib Featured

Dabrafenib (GSK2118436) is a mutant BRAFV600 specific inhibitor with IC50 of 0.8 nM, with 4- and 6-fold less potency against B-Raf(wt) and c-Raf, respectively. Phase 3.

1195765-45-7
DC4103 Dabrafenib Mesylate Featured

Dabrafenib is an orally bioavailable inhibitor of B-raf (BRAF) protein with potential antineoplastic activity.

1195768-06-9
DC7182 Dacinostat (NVP-LAQ824, LAQ824) Featured

Dacinostat (NVP-LAQ824, LAQ824) is a highly potent HDAC inhibitor with IC50 of 32 nM.

404951-53-7
DC7394 Daclatasvir dihydrochloride (BMS-790052) Featured

Daclatasvir (BMS-790052) is a highly selective inhibitor of HCV NS5A with EC50 of 9-50 pM, for a broad range of HCV replicon genotypes and the JFH-1 genotype 2a infectious virus in cell culture.

1009119-65-6
DC4197 Actinomycin D Featured

Dactinomycin (also known generically as Actinomycin D ) is the most significant member of actinomycines, which are a class of polypeptide antibiotics isolated from soil bacteria of the genus Streptomyces.

50-76-0
DC20353 Dafadine A Featured

Dafadine A is the first reported small-molecule DAF-9 cytochrome P450 inhibitor that robustly induces dauer formation in in the nematode Caenorhabditis elegans.

1065506-69-5
DC21469 Dagrocorat

Dagrocorat (PF 00251802) is a potent, selective high-affinity dissociated agonist of the glucocorticoid receptor..

1044535-52-5
DC23077 Daidzin Featured

Daidzin is a potent, selective aldehyde dehydrogenase 2 (ALDH2,IC50 = 80 nM) inhibitor, which has antiallergic anti-oxidant, anti-carcinogenic, antithrombotic,and anti-atherosclerotic activities

552-66-9
DCAPI1493 Dalbavacin Featured

Dalbavancin, a semisynthetic lipoglycopeptide being developed for the treatment of skin and skin structure infections (SSSIs), has a half-life of 5 to 7 days in humans and offers promise for a convenient weekly dosing regimen.

171500-79-1
DC3163 Dalcetrapib (JTT-705) Featured

Dalcetrapib (JTT-705) is a rhCETP inhibitor with IC50 of 0.2 μM.

211513-37-0
DC22810 Damnacanthal

Damnacanthal is a highly potent, selective inhibitor of p56 lck tyrosine kinase with IC50 of 17 nM for inhibition of p56lck autophosphorylation.

477-84-9
DC21881 Danicamtiv (MYK-491) Featured

Danicamtiv (MYK-491), an inotropic agent, is a selective allosteric activator of cardiac myosin. Danicamtiv increases cardiac systolic function and preserves mechanical efficiency.

1970972-74-7
DC11082 Danicopan (ACH-4471) Featured

Danicopan (ACH-4471, ACH-0144471) is a highly potent, orally active Factor D inhibitor with Kd of 0.54 nM, inhibits the proteolytic activity of purified Factor D against substrate Factor B in complex with C3b, blocking production of Bb fragment IC50 of 15 nM.

1903768-17-1
DC9689 Danirixin (GSK1325756) Featured

Danirixin(GSK1325756) is a selective CXCR2 antagonist.

954126-98-8
DCAPI1028 Danofloxacin Mesylate

Danofloxacin Mesylate

119478-55-6
DC8238 Danoprevir Featured

Danoprevir is a peptidomimetic inhibitor of the NS3/4A protease of hepatitis C virus (HCV) with IC50 of 0.2-3.5 nM, inhibition effect for HCV genotypes 1A/1B/4/5/6 is ~10-fold higher than 2B/3A.

850876-88-9
DC12338 Dansylamide

Dansyl amide is a fluorescent dye that is used in biochemistry and chemistry to label substances with the fluorescent dansyl group.

1431-39-6
DC8665 Dantrolene sodium hemiheptahydrate

Dantrolene sodium hemiheptahydrate is a skeletal muscle relaxant which acts by blocking muscle contraction beyond the neuromuscular junction. Dantrolene sodium hemiheptahydrate is a inhibitor of calcium channel proteins, inhibiting the release of Ca2+ fro

24868-20-0
DC9116 Dantrolene sodium

Dantrolene sodium is a inhibitor of calcium channel proteins, inhibiting the release of Ca2+ from the sarcoplasm. Dantrolene sodium is a skeletal muscle relaxant which acts by blocking muscle contraction beyond the neuromuscular junction.

14663-23-1
DC4125 PHA-739358 (danusertib) Featured

Danusertib (PHA-739358) is an Aurora inhibitor for Aurora A/B/C, Bcr-Abl, c-RET and FGFR with IC50 of 13 nM/79 nM/61 nM, 25 nM, 31 nM and 47 nM, respectively.

827318-97-8
DC6904 DAPAGLIFLOZIN Featured

Dapagliflozin, also known as BMS-512148, is a drug used to treat type 2 diabetes approved in 2012 by FDA. Dapagliflozin inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2) which are responsible for at least 90% of the glucose reabsorption in the kidney. Blocking this transporter mechanism causes blood glucose to be eliminated through the urine. In clinical trials, dapagliflozin lowered HbA1c by 0.6 versus placebo percentage points when added to metformin.

461432-26-8
DC20170 Dapagliflozin propanediol monohydrate Featured

Dapagliflozin propanediol belongs to the class of orally administered antidiabetic agents designated as sodiumglucose cotransporter 2 (SGLT2) inhibitors.

960404-48-2
DC20941 DAPH-1 Featured

DAPH-1 (CGP 52411) is a small molecule that directly inhibits prion protein Sup35 prionogenesis with IC50 of 0.58 uM, inhibits and reverses the formation of Aβ42 fibers and reduces their toxicity to neurons in culture.

145915-58-8
DC20354 DAPH-12

DAPH-12 is a small molecule that directly inhibits and reverses prion protein Sup35 prionogenesis (IC50=0.18 uM).

145915-63-5
DC7395 Dapivirine Featured

Dapivirine(TMC 120, TMC 120 R147681) is a NNRTI for HIV reverse transcriptase with IC50 of 24 nM, inhibits a broad panel of HIV-1 isolates from different classes, inclucing a wide range of NNRTI-resistant isolates.

244767-67-7
DC9630 Dapoxetine (hydrochloride) Featured

Dapoxetine HCl is a short-acting novel selective serotonin reuptake inhibitor(SSRI).

129938-20-1
DC8188 Daprodustat Featured

Daprodustat(GSK1278863) isa HIF-prolyl hydroxylase inhibitor.

960539-70-2
DC10259 Dapson

Dapsone, also known as diaminodiphenyl sulfone (DDS), is an antibiotic commonly used in combination with rifampicin and clofazimine for the treatment of leprosy.

80-08-0
DC7396 DAPT Featured

DAPT(GSI-IX) is an inhibitor of γ-secretase; DAPT causes a reduction in Aβ40 and Aβ42 levels in human primary neuronal cultures (IC50 values are 115 and 200 nM for total Aβ and Aβ42 respectively) and in brain extract, cerebrospinal fluid and plasma.

208255-80-5
DC1050 Daptomycin Featured

Daptomycin is a lipopeptide antibiotic with rapid in vitro bactericidal activity against gram-positive organisms.

103060-53-3
DC7397 Darapladib Featured

Darapladib is a selective and orally active inhibitor of Lp-PLA2 (IC50= 270 pM)

356057-34-6
DCAPI1440 Darifenacin HBr

Darifenacin Hydrobromide is an antagonist of the M3 musarinnic acetylcholine receptor.

133099-07-7
DC3152 Darifenacin

Darifenacin is a selective M3 muscarinic receptor antagonist with pKi of 8.9.

133099-04-4
DC8908 Darunavir ethanolate Featured

Darunavir ethanolate is an HIV protease inhibitor,showed potent activity against COVID-19(SARS-COV-2).

635728-49-3
DC12498 S-Darusentan Featured

Darusentan is a potent inhibitor of endothelin signaling and function in both large and small arteries.

171714-84-4
DC8647 DASA-58 Featured

DASA-58 is a highly specific small molecule PKM2 activator. DASA-58 inhibits LPS-induced Hif-1a and IL-1b, as well as the expression of a range of other Hif-1a-dependent genes.

1203494-49-8
DC2100 Dasatinib (BMS-354825) Featured

Dasatinib (BMS-354825, Sprycel) is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.5 nM and 79 nM, respectively.

302962-49-8
DC3140 Dasatinib monohydrate Featured

Dasatinib is an orally bioavailable synthetic small molecule-inhibitor of SRC-family protein-tyrosine kinases.

863127-77-9
DC21381 Dasolampanel

Dasolampanel (NGX426) is an orally bioavailable, competitive antagonist of the AMPA-kainate receptors for the treatment of chronic pain conditions including neuropathic pain and migraine..

503294-13-1
DC10073 Dasotraline Hydrochloride Featured

Dasotraline is a stereoisomer of desmethylsertraline, which is an active metabolite of the marketed selective serotonin reuptake inhibitor (SSRI) antidepressant sertraline (Zoloft) and an SNDRI similarly.

675126-08-6
DC8162 Dasotraline(SEP-225289) free base Featured

Dasotraline(SEP-225289) is a triple reuptake inhibitor that blocks dopamine, norepinephrine, and serotonin transporters with IC50 values of 4, 6, and 11 nM, respectively.

675126-05-3
DC20229 Datelliptium chloride Featured

Datelliptium chloride is a DNA-intercalating agent derived from ellipticine, with anti-tumor activities.

105118-14-7
DC9331 Daun02

Daun02 is a daunorubicin b-galactoside prodrug for use in conjunction.

290304-24-4
DC7069 Daunorubicin HCL Featured

Daunorubicin HCl inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 μM.

23541-50-6
DC25058 Daunorubicin Featured

Daunorubicin is potent topoisomerase II (Topo II) inhibitor, interacts with DNA by intercalation and inhibition of macromolecular biosynthesis in cancer cells.

20830-81-3
DC20942 DB04760

DB04760 is a potent, highly selective, non–zinc-chelating MMP-13 inhibitor with IC50 of 8 nM, displays high selectivity over other MMPs.

544678-85-5
DC8826 DB07268 Featured

DB07268 is a potent and selective JNK1 inhibitor with an IC50 value of 9 nM.

929007-72-7
DC22067 DB1055

DB1055 (DB-1055, DB 1055) is a small molecule inhibitor of HOXA9/DNA interaction through binding as minor groove DNA ligand on the HOXA9 cognate sequence.

869767-86-2
DC20943 DB2115

DB2115 is a small-molecule transcription factor PU.1 inhibitor abrogating DNA binding by PU.1 with Kd of 1.0 nM.

1366231-70-0
DC23251 DB213 Featured

DB213 (RG-501) is a small molecule stimulator of HIV-1 frameshifting and inhibitor of viral replication.

209163-39-3
DC12516 DB550

DB550 (DB-550) is a potent, peptidomimetic of calcium-inducing domain (CID) that disrupts the CD95-PLCγ1 interaction without affecting the CD95-FADD interaction binds to SH3-PLCγ1 with Kd of 40.7 uM.

DC12517 HT105

DB550 (DB-550, TCWKHRK) is a potent, peptidomimetic of calcium-inducing domain (CID) that disrupts the CD95-PLCγ1 interaction, abrogates the CD95-mediated Ca2+ response in mouse PBLs with IC50 of 38 nM.

DC22069 DB818 Featured

DB818 (DB-818, DB 818) is a small molecule inhibitor of HOXA9/DNA interaction through binding as minor groove DNA ligand on the HOXA9 cognate sequence.

790241-43-9
DC21882 DBCO acid 1

DBCO acid 1 is a Click Chemistry intermidate used for antibody-drug conjugates..

1353016-70-2
DC21883 DBCO acid 2

DBCO acid 2 is a Click Chemistry intermidate used for antibody-drug conjugates..

1207355-31-4
DC21884 DBCO acid 3

DBCO acid 3 is a Click Chemistry intermidate used for antibody-drug conjugates..

1425485-72-8
DC21885 DBCO acid 4

DBCO acid 4 is a Click Chemistry intermidate used for antibody-drug conjugates..

1618102-42-3
DC21886 DBCO acid 5

DBCO acid 5 is a Click Chemistry intermidate used for antibody-drug conjugates..

1337920-25-8
DC21888 DBCO intermidate 1

DBCO intermidate 1 is a Click Chemistry intermidate used for antibody-drug conjugates..

23112-88-1
DC21889 DBCO intermidate 2

DBCO intermidate 2 is a Click Chemistry intermidate used for antibody-drug conjugates..

23194-93-6
DC21890 DBCO intermidate 3 Featured

DBCO intermidate 3 is a Click Chemistry intermidate used for antibody-drug conjugates..

1369862-03-2
DC21891 DBCO Maleimide

DBCO Maleimide is a Click Chemistry intermidate used for antibody-drug conjugates..

1395786-30-7
DC20355 DBCO-NHS ester 2

DBCO-NHS ester 2 is a derivative of DBCO (Dibenzylcyclooctyne) used in Cu-free click chemistry.

1384870-47-6
DC22076 DBCO-NHS ester 3

DBCO-NHS ester 3 (DIBAC-NHS) is a Click Chemistry intermidate used for antibody-drug conjugates..

1393350-27-0
DC21987 DBCO-PEG4 amine

DBCO-PEG4 amine (ADIBO-PEG4-amine) is a Click Chemistry intermidate used for antibody-drug conjugates..

1255942-08-5
DC7602 DBeQ Featured

DBeQ is a selective, potent, reversible, and ATP-competitive p97 inhibitor with IC50 of 1.5 μM.

177355-84-9
DC12023 dBET1 Featured

dBET1 is a potent BRD4 protein degrader based on PROTAC technology with an EC50 of 430 nM.

1799711-21-9
DC21892 dBET23

dBET23 is a BRD4 heterobifunctional small-molecule ligand (PROTAC), exhibits significant and selective degradation of BRD4 BD1 (DC50/5h=50 nM) in cellular degradation assays..

1957234-83-1
DC21893 dBET57 Featured

dBET57 is a novel BRD4 heterobifunctional small-molecule ligand (PROTAC), exhibits significant and selective degradation of BRD4 BD1 (DC50/5h=500 nM), but is inactive on BRD4 BD2..

1883863-52-2
DC12022 dBET6 Featured

dBET6 is a highly potent, selective and cell-permeable degrader of BET with an IC50 of 14 nM, and has antitumor activity.

1950634-92-0
DC8108 DBPR108

DBPR108 is a potent, selective, and orally bioavailable dipeptide-derived inhibitor of DPP4 with IC50 of 15 nM; no inhibition on DDP8 and DPP9. IC50 value: 15 Nm.

1186426-66-3
DC12665 DBPR114 Featured

DBPR114 is a quinazoline-based multi-kinase inhibitor for the treatment of acute myeloid leukemia and other solid tumors.

DC7790 CB1-IN-1(BPRCB1184) Featured

CB1-IN-1 (BPRCB1184) is a peripherally restricted CB1R antagonist, with Ki of 0.3 nM and 21 nM for CB1R (EC50 = 3 nM) and CB2R, respectively. IC50 value: 0.3 nM (Ki, CB1R) 21 nM (Ki, CB2R) Target: CB1R in vivo: CB1-IN-1 is a novel peripherally restricted cannabinoid 1 receptor antagonist with significant weight-loss efficacy in diet-induced obese mice. CB1-IN-1 has great potential to ameliorate this related metabolic syndrome.

1429239-98-4
DC11589 dBRD9 Featured

dBRD9 is a PROTAC that bridge the BRD9 bromodomain and the cereblon E3 ubiquitin ligase complex.

2170679-45-3
DC23976 DC_517

DC_05 is a potent, selective, non-nucleoside DNA methyltransferase DNMT1 inhibitor with IC50 of 1.7 uM, displays significant selectivity toward other AdoMet-dependent protein methyltransferases.

500017-70-9
DC23977 DC-05 Featured

DC-05 is a selective, non-nucleoside DNA methyltransferase DNMT1 inhibitor with IC50 of 10.3 uM, displays 3.6-fold selectivity over PRMT1 and >15-fold over DNMT3A, DNMT3B, G9a, SUV39H1, MLL1, SET7/9..

890643-16-0
DC20945 DC_AC50 Featured

DC_AC50 (DCAC50) is a small molecule that inhibits the human copper chaperones Atox1 and CCS (Kd=6.8 and 8.2 uM), blocks copper trafficking and significantly attenuates cancer cell proliferation.

497061-48-0
DC12361 DC1

DC1, an analogue of the minor groove-binding DNA alkylator CC-1065, is an antibody conjugate of cytotoxic DNA alkylators for the targeted treatment of cancer.

169901-27-3
DC12055 DC1-SMe

DC1-Sme is an antibody conjugate of phosphate prodrug of cytotoxic DNA alkylators for the targeted treatment of cancer.

501666-85-9
DC10554 DC260126 Featured

DC260126, a small-molecule antagonist of GPR40.

346692-04-4
DC12554 DC661 Featured

DC661 (DC-661) is a novel dimeric chloroquine (CQ) that is capable of deacidifying the lysosome and inhibiting autophagy significantly better than HCQ, targets palmitoyl-protein thioesterase 1 (PPT1).

1872387-43-3
DC5041 DCC-2036 (Rebastinib) Featured

DCC-2036 is a conformational control Bcr-Abl inhibitor for Abl1(WT) and Abl1(T315I) with IC50 of 0.8 nM and 4 nM, also inhibits SRC, LYN, FGR, HCK, KDR, FLT3, and Tie-2, and low activity to seen towards c-Kit. Phase 1/2.

1020172-07-9
DC9585 c-Kit-IN-1(DCC-2618) Featured

DCC-2618 is a small molecule inhibitor of c-Kit and PDGFR with IC50s of 6 nM/30 nM/13 nM for c-Kit/PDGFRα/PDGFRβ respectively.

1225278-16-9
DC20175 Ripretinib (DCC-2618) Featured

DCC-2618 is an orally bioavailable switch pocket control inhibitor of wild-type and mutated forms of the tumor-associated antigens (TAA) mast/stem cell factor receptor (SCFR) KIT and PDGFR-alpha, with IC50 values of 4 nM, 8 nM, 18 nM, 5 nM and 14 nM.

1442472-39-0
DC24137 DCVC

DCVC (S-(1,2-dichlorovinyl)-L-cysteine) is an active metabolite of trichloroethylene.

13419-46-0
DCAPI1304 D-Cycloserine

D-Cycloserine

68-41-7
DC12593 DD-03-171

DD-03-171 is a small molecule, CGI1746-based BTK degrader (PROTAC, biochemical IC50=5.1 nM) that efficiently degrade C481S-BTK, exhibits enhanced anti-proliferative effects on mantle cell lymphoma (MCL) cells in vitro by degrading BTK, IKFZ1 and IKFZ3.

DC20947 DDD 85646 Featured

DDD 85646 is a potent, specific, dual N-Myristoyltransferase NMT1/NMT2 inhibitor with IC50 of 17 nM/22 nM respectively.

1215010-55-1
DC10413 DDP-38003 dihydrochloride

DDP-38003 dihydrochloride is an novel, orally available inhibitor of histone lysine-specific demethylase 1A (KDM1A/LSD1) with an IC50 of 84 nM.

1831167-98-6
DC10996 DDR inhibitor X Featured

DDR inhibitor X is a potent discoidin domain receptor (DDR) inhibitor with IC50 of 3.3 nM for DDR2, and shows 53% inhibition on DDR1 at 1.5 nM..

1644069-80-6
DC12521 DDR1 inhibitor 2.45

DDR1 inhibitor 2.45 (Compound 2.45) is a novel potent, selective, bioavailable Discoidin Domain Receptor 1 (DDR1) inhibitor with IC50 of 29 nM, displays 64-fold selectivity over DDR2 in biochemical assays.

2125676-13-1
DC23844 DDR1 inhibitor 7rh

DDR1 inhibitor 7rh is a potent, selective, ATP-competitive, orally available Discoidin domain receptor 1 (DDR1) inhibitor with IC50 of 6.8 nM in cell-free kinase assays.

1429617-90-2
DC7398 DDR1-IN-1 Featured

DDR1-IN-1 is a potent and selective DDR1 receptor tyrosine kinase inhibitor with IC50/EC50 of 105 nM/87 nM; 4-fold less potent for DDR2 (IC50= 413 nM).

1449685-96-4
DC23857 DDR2-IN-5

DDR2-IN-5 is a potent, dual DDR2/SRC inhibitor with IC50 of 56/12 nM, potently suppresses DDR2 mutated cell lines HCC-366 and NCI-H2286 with IC50 of 0.44 uM and 0.29 uM..

1796592-06-7
DC12560 DDR-TRK-1

DDR-TRK-1 (DDR1 inhibitor 6j) is a potent, selective selective DDR1 inhibitor with IC50 of 9.4 nM, also potently inhibits TRK family with IC50 of 18-100 nM.

1912357-12-0
DC10111 Debio 0617B

Debio 0617B has been developed as a first-in-class kinase inhibitor with a unique profile targeting phospho-STAT3 (pSTAT3) and/or pSTAT5 in tumors through combined inhibition of JAK, SRC, ABL, and class III/V receptor tyrosine kinases (RTK).

1332329-27-7
DC7390 CUDC-305(DEBIO 0932) Featured

Debio 0932 ( CUDC-305 ) is a novel heat shock protein 90 (HSP90) inhibitor trong affinity for HSP90 alpha/beta, high oral bioavailability and potent anti-proliferative activity against a broad range of cancer cell lines (with a mean IC50 of 220 nmol/L) .

1061318-81-7
DC8171 Decernotinib (VX-509,adelatinib) Featured

Decernotinib(VX-509; VRT-831509) is a potent and selective Janus kinase 3 (JAK3) inhibitor with Ki of 2.5 nM; IC50 is 50-170 nM in cellular assays.

944842-54-0
DC4193 Decitabine Featured

Decitabine is a potent inhibitor of DNA methylation with IC50 of 438 nM and 4.38 nM in HL-60 and KG1a cells, respectively.

2353-33-5
DC12144 Decursin ((+)-Decursin) Featured

Decursin is an anticancer agent, with potential anti-inflammatory activity.

5928-25-6
DC7695 Defactinib (VS-6063, PF-04554878) Featured

Defactinib is a potent, selective, and orally active FAK inhibitor with demonstrated tolerability and preliminary clinical activity working as a single agent as well as in combination with paclitaxel.

1073154-85-4
DC10100 Defactinib hydrochloride Featured

Defactinib is a potent, selective, and orally active FAK inhibitor with demonstrated tolerability and preliminary clinical activity working as a single agent as well as in combination with paclitaxel.

1073160-26-5
DC10822 Defensamide(MHP) Featured

Defensamide, also known as MHP and methyl caprooyl tyrosinate, is an activator of sphingosine kinase (SPHK1), and significantly stimulates CAMP mRNA and protein production in KC.

1104874-94-3
DCAPI1107 Deferasirox (Exjade) Featured

Deferasirox (Exjade)

201530-41-8
DC7399 Deferitrin Featured

Deferitrin (GT-56-252) is the first drug in a class of desferrithiocin-derived hexadentate iron chelators.

239101-33-8
DC11332 Degarelix (acetate) Featured

Degarelix is a synthetic gonadotropin-releasing hormone receptor (GNRHR) antagonist (IC50 = 3 nM in HEK293 cells expressing the human receptor).

214766-78-6
DC9337 Deguelin Featured

Deguelin, a naturally occurring rotenoid, is known to be an Akt inhibitor and to have an anti-tumor effect on several cancers; decrease levels of phosphorylated Akt.

522-17-8
DC5201 Dehydroepiandrosterone (DHEA)

Dehydroepiandrosterone(DHEA) is a 19-carbon endogenous natural steroid hormone.

53-43-0
DC23727 Dehydromutactin

Dehydromutactin is a small molecule inhibitor of RNA-binding protein Hu protein R (HuR) that interferes the HuR homodimerization with Kd of 40 nM.

823803-77-6
DC12073 Dehydronitrosonisoldipine

Dehydronitrosonisoldipine is a calcium channel antagonist.

87375-91-5
DC8866 DEL-22379 Featured

DEL-22379 is a water-soluble ERK dimerization inhibitor with IC50 of ∼0.5 μM.

181223-80-3
DC10458 Delafloxacin(ABT-492) Featured

Delafloxacin (RX-3341, ABT-492) is a fluoroquinolone antibiotic agent.

189279-58-1
DC20116 Delafloxacin meglumine (ABT492 meglumine; RX-3341 meglumine; WQ-3034 meglumine) Featured

Delafloxacin meglumine (ABT492 meglumine; RX-3341 meglumine; WQ-3034 meglumine) is a broad-spectrum fluoroquinolone antibiotic. Delafloxacin has a broad spectrum of activity that includes drug-resistant Staphylococcus aureus, Streptococcus pneumoniae, and

352458-37-8
DC7764 Delamanid (OPC-67683) Featured

Delamanid (OPC-67683) is an experimental drug for the treatment of multi-drug-resistant tuberculosis.

681492-22-8
DC8481 Delanzomib(CEP-18770) Featured

Delanzomib(CEP-18770) is a novel orally-active inhibitor of the chymotrypsin-like activity of the proteasome that down-modulates the nuclear factor-kappaB (NF-kappaB) activity.

847499-27-8
DC11352 Delavirdine (mesylate)

Delavirdine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that selectively inhibits HIV-1 reverse transcriptase over DNA polymerase α and δ in vitro (IC50s = 0.26, 440, and >550 μM, respectively).

147221-93-0
DC8897 Delavirdine

Delavirdine(U 90152) is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI).

136817-59-9
DC20772 Deleobuvir

Deleobuvir (BI-207127, BI207127) is a potent, selective HCV NS5B polymerase inhibitor with IC50 of 50 nM against GT-1 HCV polymerase activity.

863884-77-9
DC11890 Delgocitinib Featured

Delgocitinib (JTE-052, LEO 124249) is a potent, selective, orally active, pan-JAK inhibitor with IC50 of 2.8, 2.6, 13 and 58 nM for JAK1,2,3 and Tyk2, respectively.

1263774-59-9
DC10612 Delpazolid (LCB01-0371) Featured

Delpazolid (LCB01-0371) is a new oxazolidinone with cyclic amidrazone.

1219707-39-7
DC8205 Deltarasin Featured

Deltarasin is a novel and small molecule inhibitor which can inhibit the KRAS-PDEδ interaction(Kd= 41 nM. binding to PDEδ) and impairs oncogenic KRAS signalling.

1440898-61-2
DC20948 Deltasonamide 2

Deltasonamide 2 (Deltasonamide-2) is a novel small molecule inhibitor of PDE6δ/KRas interaction with Kd of 385 pM.

2088485-34-9
DC26004 delta-Valerobetaine (hydrobromide) Featured

Delta-Valerobetaine (hydrobromide) is a precursor of trimethylamine N-oxide (TMAO).

66258-96-6
DC12287 delta-Valerobetaine Featured

Delta-Valerobetaine is a precursor of trimethylamine N-oxide (TMAO).

6778-33-2
DC20949 Deltazinone 1

Deltazinone 1 (Deltazinone1) is a novel highly selective PDEδ inhibitor that inhibits PDEδ/Ras interaction with Kd of 8±4 nM.

894554-89-3
DC10850 Dencichine

Dencichin is a non-protein amino acid originally extracted from Panax notoginseng, and can inhibit HIF-prolyl hydroxylase-2 (PHD-2) activity.

5302-45-4
DC7199 Denibulin (MN-029)

Denibulin (MN-029) is a novel vascular-disrupting agent that reversibly inhibits microtubule assembly, resulting in disruption of the cytoskeleton of tumor vascular endothelial cells.

779356-64-8
DC8712 Deoxycorticosterone acetate Featured

Deoxycorticosterone acetate is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as a precursor to aldosterone.

56-47-3
DC10308 Deoxycytidine triphosphate

Deoxycytidine triphosphate (dCTP), a nucleoside triphosphate, is a raw material in DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

2056-98-6
DC23791 Deoxyspergualin

Deoxyspergualin is a derivative of the antitumor antibiotic spergualin that binds specifically to Hsc70, also inhibits poly(rC) binding protein 2 (PCBP2)..

98629-43-7
DC8911 Deracoxib

Deracoxib, a selective cyclooxygenase-2 inhibitor, is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID).

169590-41-4
DC10559 Derazantinib (ARQ 087) Featured

Derazantinib (Derazantinib) is an ATP competitive tyrosine kinase inhibitor; exhibits potent activity against FGFR1-3 chondrocytes with IC50s of 4.5, 1.8, and 4.5 nM, respectively.

1234356-69-4
DC24197 Derenofylline(SLV320) Featured

Derenofylline(SLV320) is a potent and selective adenosine A1 receptor antagonist (Ki values are 1, 200, 398 and 3981 nM at human A1, A3, A2A and A2B receptors respectively).

251945-92-3
DC11402 Desidustat Featured

Desidustat is an inhibitor of HIF hydroxylase.

1616690-16-4
DC9057 Desloratadine

Desloratadine(Sch34117) is a potent antagonist for human histamine H1 receptor used to treat allergies.

100643-71-8
DC11055 Desmethyl dabrafenib Featured

Desmethyl dabrafenib (GSK2167542, Dabrafenib metabolite M8) is the desmethyl- metabolic byproduct of Dabrafenib, ameliorates developmental pathologies of Kabuki Syndrome in vivo..

1195765-47-9
DC8833 Desmethyl VS-5584 Featured

Desmethyl VS-5584 is a PI3K/mTOR kinase inhibitor

1246535-95-4
DC9604 Desogestrel Featured

Desogestrel(Org-2969) is a third-generation 19-nortestosterone derivative progestogen; is contained in many oral contraceptive preparations, both combined (COCs) to ethinyl-estradiol (EE) or alone in a progestin-only pill (POP).

54024-22-5
DCAPI1287 Desonide

Desonide

638-94-8
DC11331 Desoximetasone

Desoximetasone is a glucocorticoid.

382-67-2
DC9631 Desvenlafaxine (succinate hydrate)

Desvenlafaxine succinate hydrate is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI).

386750-22-7
DC8097 Detomidine hydrochloride

Detomidine hydrochloride produce dose-dependent sedative and analgesic effects, is a nonnarcotic, synthetic α2-adrenergic agonist

90038-01-0
DC20273 Deuterated AZ5104 Featured

Deuterated AZ5104 is a potent EGFR inhibitor.

2129998-32-7
DCAPI1025 Dexamethasone Featured

Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs used as an anti-inflammatory and immunosuppressant.

50-02-2
DC4240 Dexmedetomidine hydrochloride Featured

Dexmedetomidine Hydrochloride is an agonist of adrenergic alpha-2 receptor, which is used in veterinary medicine for its analgesic and sedative properties.

145108-58-3
DC10231 D panthenol

Dexpanthenol is an alcoholic analogue of D-pantothenic acid and cholinergic agent.

81-13-0
DCAPI1475 Dexrazoxane Hydrochloride

Dexrazoxane Hydrochloride

149003-01-0
DCAPI1431 Dextromethorphan hydrobromide

Dextromethorphan hydrobromide

125-69-9
DC9093 Dextromethorphan HBr

Dextromethorphan hydrobromide hydrate is an antitussive drug.

6700-34-1
DC23104 D-Fagomine

D-Fagomine (Fagomine) is a a mild glycosidase inhibitor, inhibits Amyloglucosidase (A.niger), β-Glucosidase (bovine), and Isomaltase (yeast) with Ki of 4.8 uM, 39 uM, and 70 uM, respectively.

53185-12-9
DC22187 DFMO

DFMO (Ornithine Decarboxylase inhibitor DFMO) is an irreversible inhibitor of ornithine decarboxylase (ODC), inhibits polyamine biosynthesis.

68278-23-9
DC22074 DFP00173 Featured

DFP00173 (DFP-00173) is a potent and selective aquaporin-3 (AQP3) inhibitor, inhibits glycerol permeability in erythrocytes with IC50 of 0.2 uM..

672286-03-2
DC24079 DG-172 dihydrochloride Featured

DG-172 is a novel PPARβ/δ-selective ligand showing high binding affinity (IC50= 27 nM) and potent inverse agonistic properties.

1361504-77-9
DC20357 D-G23

D-G23 is a small molecule that inhibits RAD52-mediated ssDNA annealing with IC50 of 5.8 uM, binds to RAD52 with Kd of 34 uM and inhibits D-loop formation with IC50 of 7.2 uM in vitro.

1225141-73-0
DC9414 DGAT-1 inhibitor 2

DGAT-1 inhibitor 2 is an effective inhibitor of DGAT-1;antiobesity agents.

942999-61-3
DC23686 DGAT1-IN-1

DGAT1-IN-1 is a potent DGAT1 inhibitor with IC50 of < 10 nM..

1449779-49-0
DC20358 DGAT2 inhibitor 2

DGAT2 inhibitor 2 is a novel potent, selective DGAT2 inhibitor with IC50 of 6 nM (hDGAT2), shows no significant activity for DGAT1 (IC50>20 uM).

DCAPI1274 D-glutamine

D-glutamine is a D type stereoisomer of glutamine which is one of the 20 amino acids encoded by the standard genetic code.

5959-95-5
DC20953 DH-376

DH-376 is a highly potent dual DAGLα/β inhibitor with IC50 of 6 nM and 3-8 nM, respectively.

1848233-57-7
DC20937 D-I03

D-I03 (D-103) is a small molecule that inhibits RAD52-mediated ssDNA annealing with IC50 of 5 uM, binds to RAD52 with Kd of 25.8 uM and inhibits D-loop formation with IC50 of 8 uM in vitro.

688342-78-1
DC20954 DI-404

DI-404 is a highly potent, peptidomimetic inhibitor of DCN1-UBC12 protein-protein interaction that bind to DCN1 protein with Kd of 6.9 nM, selectively inhibits the neddylation of cullin 3 over other cullin members.

DC11500 DI-591

DI-591 (DI591) is a potent, selective, cell-permeable inhibitor of the DCN1-UBC12 interaction with Ki of 10-12 nM for human DCN1 and DCN2.

2245887-38-9
DC12321 STING agonist-1 trihydrochloride Featured

diABZI STING agonist-1 (trihydrochloride) is a selective stimulator of interferon genes (STING) receptor agonist.

2138299-34-8
DC12077 Diacylglycerol acyltransferase inhibitor-1

Diacylglycerol acyltransferase inhibitor-1 is a diacylglycerol acyltransferase (DGAT1) inhibitor.

1610800-25-3
DC10060 Dianilinopyrimidine_01(CZC8004) Featured

Dianilinopyrimidine_01 is a Pan Tyrosine kinase inhibitor.

916603-07-1
DC23201 Diarylpropionitrile Featured

Diarylpropionitrile (DPN) is a non-steroidal estrogen receptor β(ERβ) selective ligand, demonstrates the neuroprotective effects against 10 0M Aβ1-42-induced oxidative stress and inflammation in primary rat cortical cell culture.

1428-67-7
DC23747 Diazepinomicin

Diazepinomicin (TLN 4601.

733035-26-2
DC10270 Diazoxide

Diazoxide is a well-known small molecule that activates KATP channels in the smooth muscle of blood vessels and pancreatic beta-cells by increasing membrane permeability to potassium ions.

364-98-7
DC20153 Dibutyl phthalate Featured

Dibutyl phthalate is a commonly used plasticizer commonly found in some food packaging materials, personal care products, and the coating of oral medications. May cause toxicity and adverse neurobehavioral effects.

84-74-2
DC8394 Dibutyryl-cAMP (Bucladesine) Featured

Dibutyryl-cAMP (Bucladesine) is a cell-permeable PKA activator by mimicing the action of endogenous cAMP.

16980-89-5
DCAPI1032 Dichlorphenamide (Diclofenamide) Featured

Dichlorphenamide (Diclofenamide)

120-97-8
DC8918 Diclazepam

Diclazepam(Ro5-3448; Chlorodiazepam) is an analogue of diazepam; are similar to diazepam, possessing anxiolytic, anticonvulsant, hypnotic, sedative, skeletal muscle relaxant, and amnestic properties.

2894-68-0
DC9064 Diclofenac sodium

Diclofenac Sodium is a non-selective COX inhibitor with IC50 of 60 and 220 nM for ovine COX-1 and -2, respectively.

15307-79-6
DCAPI1300 Diclofensine (Ro 8-4650) Featured

Diclofensine(Ro-8-4650) is a potent inhibitor of monoamine reuptake, blocking the uptake of dopamine, noradrenaline, and serotonin by rat brain synaptosomes with IC50 values of 0.74, 2.3, and 3.7 nM, respectively.

67165-56-4
DC20359 Dicycloplatin

Dicycloplatin (DCP) is a novel platinum analog that demonstrates significant antitumor activity against a variety of human cancer cell lines with IC50 of 25-30 nM.

287402-09-9
DC9481 Didanosine

Didanosine(Videx) is a reverse transcriptase inhibitor with an IC50 of 0.49 μM. Target: NRTIs; HIV Didanosine is a dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen.

69655-05-6
DC22178 Didemethylclomipramine

Didemethylclomipramine (Norclomipramine, N-Desmethylcomipramine) is the major active metabolite of the tricyclic antidepressant (TCA) clomipramine.

303-48-0
DC8827 Didox Featured

Didox is a simple, synthetic antioxidant that has been found to reduce the levels of oxidative injury markers.

69839-83-4
DC9605 Dienogest

Dienogest(STS-557) is a specific progesterone receptor agonist with potent oral endometrial activity and is used in the treatment of endometriosis.

65928-58-7
DC9890 Diethyl maleate

Diethylmaleate is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NFkB.

141-05-9
DC12140 Diethyl-pythiDC

Diethyl-pythiDC is an inhibitor of collagen prolyl 4-hydroxylases (CP4Hs).

1821370-70-0
DC21445 Difamilast Featured

Difamilast (OPA-15406) is a novel potent, selective phosphodiesterase IV (PDE4) inhibitor with preference for PDE4B (IC50=11.2 nM).

937782-05-3
DC10256 Diflunisal

Diflunisal is a difluorophenyl derivate of salicylic acid and a nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic and anti-inflammatory properties. The mechanism of action of diflunisal is as a Cyclooxygenase Inhibitor.

22494-42-4
DC9551 Difluprednate Featured

Difluprednate(Durezol) is a corticosteroid, approved difluprednate for the treatment of post-operative ocular inflammation and pain.

23674-86-4
DC12167 Digitonin Featured

Digitonin, a glycoside obtained from Digitalis purpurea, could increase cell permeability by binding to cholesterol molecules and reduce tumor growth.

11024-24-1
DC9760 Dihexa (PNB-0408) Featured

Dihexa is an oligopeptide drug that binds with high affinity to hepatocyte growth factor (HGF) and potentiates its activity at its receptor, c-Met.

1401708-83-5
DC23085 Dihydrocapsaicin

Dihydrocapsaicin, a potential inducer of autophagy, has cytotoxic activity. It has anti-atherogenic activity, can reduce the susceptibility of low-density lipoprotein (LDL) to oxidation. Dihydrocapsaicin treatment depletes peptidergic nerve fibers of subs

19408-84-5
DC8274 Dihydroethidium Featured

Dihydroethidium(Hydroethidine; PD-MY 003) is a superoxide indicator; exhibits blue-fluorescence in the cytosol until oxidized, where it intercalates within the cell's DNA, staining its nucleus a bright fluorescent red.

104821-25-2
DC10176 Dihydroisotanshinone I

Dihydroisotanshinone I is a bioactive compound present in a widely used traditional Chinese medicine named danshen.

20958-18-3
DC11961 Dihydromunduletone

Dihydromunduletone is a rotenoid derivative that selectively inhibits GPR56 (IC50=21 uM) and GPR114/ADGRG5, but not GPR110 or Class A GPCRs.

674786-20-0
DCAPI1152 Diltiazem HCl (Tiazac)

Diltiazem HCl (Tiazac)

33286-22-5
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