| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC39815 | Tafluprost Featured | Tafluprost(AFP-168) is an anti-glaucoma prostaglandin (PG) analog.A number of 17-phenyl trinor PGF2α derivatives have been approved for the treatment of glaucoma.1,2,3,4 Of these, the ones wherein the 13,14-double bond has been hydrogenated retain relatively good potency. |
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| DC22709 | LY3027788 | A orally active prodrug of LY3020371, which is a potent, selective metabotropic glutamate 2/3 receptor (mGlu2/3) antagonist with Ki of 5.3 and 2.5 nM, respectively. |
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| DC11882 | HJC0416 | A orally bioavailable small-molecule STAT3 inhibitor. |
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| DC22989 | BMS-204493 Featured | A pan-RAR inverse agonist that blocks RARα activity with IC50 of 114 nM. |
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| DC23094 | TRAP-6 Featured | A PAR1 peptide fragment (residues 42-47) that acts as a PAR1 agonist. |
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| DC22372 | Dexpramipexole Featured | A partial/full agonist of dopamine receptor with Ki of 3.9/2.2/0.5/5.1 nM for D2S/D2L/D3/D4, respeectively. |
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| DC22373 | Dexpramipexole dihydrochloride Featured | Dexpramipexole 2Hcl(KNS-760704), also known as R-(+)-Pramipexole, is a neuroprotective agent and weak non-ergoline dopamine agonist. IC50 Value:Target: Dopamine ReceptorDexpramipexole has been found to have neuroprotective effects and is being investigated for treatment of amyotrophic lateral sclerosis (ALS). Dexpramipexole reduces mitochondrial reactive oxygen species (ROS) production, inhibits the activation of apoptotic pathways, and increase cell survival in response to a variety of neurotoxins and β-amyloid neurotoxicity. Compared to the S-(-) isomer, Dexpramipexole has much lower dopamine agonist activity. |
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| DC8496 | CTP 518(Atazanavir, deuterated) | A partially dueterated analog of Atazanavir, an oral HIV protease inhibitor; A deuterium-containing medicine with improved ADME properties; Compound 120 showed an approximately 50% increase in half life compared with Atazanavir. |
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| DC11591 | Bis-PEG4-acid | A PEG linker for PROTAC.. |
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| DC11592 | Bis-PEG5-acid | A PEG linker for PROTAC.. |
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| DC11593 | Bis-PEG6-acid | A PEG linker for PROTAC.. |
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| DC11583 | N3-PEG2-CH2COOH | A PEG2 linker for PROTAC.. |
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| DC11577 | N3-PEG3-CH2COOH | A PEG3 linker for PROTAC.. |
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| DC11582 | N3-PEG4-CH2COOH | A PEG4 linker for PROTAC.. |
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| DC22356 | Capreomycin sulfate | A peptide antibiotic, commonly grouped with the aminoglycosides, which is given in combination with other antibiotics for MDR-tuberculosis. . |
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| DC23934 | FTI-277 Featured | A peptide mimetic of the C-terminal Cys-Val-Ile-Met of K-Ras4B that potently inhibits FTase (Farnesyltransferase) with IC50 of 0.5 nM. |
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| DC20311 | Apraglutide Featured | A peptidic glucagon like peptide 2 (GLP-2) analogue for treatment of type2 diabetes.. |
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| DC24173 | Tolfenpyrad | A pesticide agent.. |
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| DC22952 | (S) 93-31 | A pH-dependent, GluN2B-selective inhibitor of NMDA receptor with IC50 of 0.19 uM at pH6.9, 10-fold selecivity over brain tissue pH 7.6 (IC50=1.8 uM). |
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| DC24170 | TBHQ | A phenolic antioxidant and a selective inducer and activator of Nrf2 that ameliorates doxorubicin-induced cardiotoxicity in vivo. |
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| DC22501 | Fosamprenavir calcium | A phosphate ester prodrug of the HIV-1 protease inhibitor amprenavir with improved solubility.. |
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| DC22845 | Disoxaril | A picornavirus replication inhibitor by binding to the hydrophobic pocket within the VP1 coat protein, thus stabilizing the virion and blocking its uncoating.. |
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| DC22620 | Tiadinil | A plant activator of systemic acquired resistance, boosts the production of herbivore-induced plant volatiles. |
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| DC5895 | Apigenin | A plant flavonoid that has been found to inhibit cell proliferation by arresting the cell cycle at the G2/M phase. |
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| DC5880 | Piceatannol | A plant metabolite possessing anti-leukemic activity; inhibits the non-receptor kinases, Syk and Lck. |
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| DC12009 | CPA-7 | A platinum-containing compound that disrupts STAT3 signaling, inhibits cell growth and induces apoptosis in STAT3-activated cancer cells. |
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| DC22782 | MDL-72527 Featured | A polyamine oxidase (PAO) inhibitor that inhibits spermine oxidase and N1-acetylpolyamine oxidase with IC50 of 6.1 and 0.02 uM, respectively. |
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| DC22387 | Nystatin | A polyene antifungal antibiotic that works by disrupting the cell membrane of the fungal cells.. |
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| DC22957 | RU-TRAAK-1 | A poorly reversible TRAAK inhibitor, shows no activity for non-K2P channels (Kv1.2, Slo1 and GIRK2).. |
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| DC22647 | NU-7163 | A poten and selective, ATP-competitive DNA-PK inhibitor with IC50 of 0.19 uM, Ki of 24 nM. |
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