6-MITC is an inhibitor of viability of both PANC-1 and BxPC-3 cells. It also acts as an inhibitor of the expression of CSC signaling molecule SOX2.

6-MOMIPP is a novel microtubule disruptor that targets the colchicine binding site on β-tubulin, induces mitotic arrest, caspase activation and loss of cell viability of U251 glioblastoma in vitro.

6-OAU(GTPL5846; 6-n-octylaminouracil) is a surrogate agonist of GPR84; activates human GPR84 in the presence of Gqi5 chimera in HEK293 cells with an EC50 of 105 nM in the PI assay.

6-Thioguanine(6-TG) belongs to the thiopurine family of drugs that also include mercaptopurine and azathioprine, which are examples of antimetabolites; it is a purine analogue of the nucleobase guanine.

7,8-Dihydroxyflavone acts as a potent and selective small-molecule agonist of the TrkB receptor (Kd ≈ 320 nM), the main signaling receptor of brain-derived neurotrophic factor (BDNF).

7ACC2 is a new potent MCT inhibitor with IC50 of 11 nM for inhibition of [14C]-lactate influx; new antitumor treatment targeting lactate transport in cancer cells.

7-Aminocephalosporanic acid is used for synthesis of cephalosporin antibiotics and intermediates.

7-BIA is a small molecule 7-butoxy illudalic acid analog that targets receptor-type protein tyrosine phosphatase D (PTPRD, IC50=1-3 uM) with some specificity.

7-Dehydrocholesterol is biosynthetic precursor of cholesterol and vitamin D3.

7DG (7-Desacetoxy-6,7-dehydrogedunin) is a selective inhibitor of protein kinase R (PKR) that directly interact with the C-terminal of PKR.

7-Epi 10-Desacetyl Paclitaxel is a paclitaxel impurity. The compound, originally isolated from Taxus yunnanensis, has shown potential growth inhibitory activities against human cancer cells.

7-epi-Taxol is a paclitaxel binds to tubulin, interfering with the normal function of microtubule.

8-Bromo-cAMP is a cell perbeable cyclic AMP (cAMP) analog and a PKA activator.

8-Hydroxy-efavirenz is the primary metabolite of the antiretroviral drug Efavirenz, stimulates the glycolytic flux in cultured rat astrocytes.

8-O-Acetyl shanzhiside methyl ester (ND01) is an iridoid glucoside isolated from the leaves of Lamiophlomis rotata Kudo, a Chinese folk medicinal plant in Xi-zang.

8-OH-DPAT is a research chemical of the aminotetralin chemical class and has been widely used to study the function of the 5-HT1A receptor.

A 10-fold more potent lysosomal autophagy inhibitor than hydroxychloroquine (HCQ)..

A 2-cyanoaziridine derivative with antitumor activity in some types of cancer, including pancreatic, lung, breast, prostate, melanoma, and multiple myeloma.

A 385358 is a potent, selective, cell-permeable Bcl-XL inhibitor with Ki of 0.8 nM, displays >80-fold selectivity over Bcl-2 (Ki=64 nM).

A 4′-azidocytidine analogue that shows anti-HCV activity..

A 4′-azidocytidine analogue that shows anti-HCV activity..

A 419259 3Hcl is an apoptosis inducing agent that inhibits Src family kinases (c-Src).