| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC22917 | SCH 79797 dihydrochloride Featured | A potent, selective competitive and nonpeptide PAR-1 antagonist with IC50 of 70 nM. |
|
| DC20580 | Vitacoxib | A potent, selective COX-2 inhibitor with IC50 of 0.34 ug/mL, >50-fold selectivity over COX-1 (IC50=19.4 ug/mL). |
|
| DC11675 | Synta-66 | A potent, selective CRAC channel Orai1 blocker with IC50 of 3 uM. |
|
| DC22418 | CCX-771 | A potent, selective CXCR7 antagonist with IC50 of 4.1 nM. |
|
| DC22912 | SCH39166 | A potent, selective D1 dopamine receptor antagonist with Ki of 3.6 nM, >300-fold selectivity over D2 and 5-HT2 receptors. |
|
| DC11897 | Garvagliptin | A potent, selective dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment for type 2 diabetes.. |
|
| DC12015 | SKF 83566 hydrobromide | A potent, selective dopamine D1 receptor antagonist with Ki of 0.56 nM. |
|
| DC22910 | ABT-724 | A potent, selective dopamine D4 receptor agonist that activates human dopamine D4 receptors with EC50 of 12.4 nM, with no effect on dopamine D1, D2, D3, or D5 receptors. |
|
| DC22909 | ABT-724 trihydrochloride | A potent, selective dopamine D4 receptor agonist that activates human dopamine D4 receptors with EC50 of 12.4 nM, with no effect on dopamine D1, D2, D3, or D5 receptors. |
|
| DC11973 | A-412997 | A potent, selective dopamine D4 receptor agonist with Ki of 12.1 and 7.9 nM for rat and human D4 receptors, respectively. |
|
| DC11866 | AZD 3147 Featured | A potent, selective dual mTORC1 and mTORC2 inhibitor with enzyme IC50 of 1.5 nM. |
|
| DC22586 | AZD9496 maleate | A potent, selective estrogen receptor downregulator (SERD) with ER downregulation pIC50 of 9.68. |
|
| DC20378 | FABP4 inhibitor 1 | A potent, selective FABP4 inhibitor with Ki of 30 nM.. |
|
| DC11956 | CCG 258748 | A potent, selective G protein-coupled receptor kinase GRK2 inhibitor with IC50 of 8 nM. |
|
| DC22881 | GLP1-agonist-1 | A potent, selective GLP-1 agonist. |
|
| DC20392 | GLUT4-IN-17 | A potent, selective glucose transporter 4 (GLUT4) inhibitor with IC450 of 10.8 uM, inhibits MM cell proliferation. |
|
| DC22747 | AICP | A potent, selective GluN2C-selective NMDA receptor glycine site superagonist with EC50 of 1.7 nM at GluN1/2C. |
|
| DC11838 | Org 25935 | A potent, selective glycine transporter 1 (GlyT1) inhibitor with IC50 of 100 nM. |
|
| DC23558 | (+)-NFPS | A potent, selective GlyT1 inhibitor that demonstrates >10-fold greater activity in in vitro functional glycine reuptake assay than racemic (±)-NFPS. |
|
| DC11616 | KUNG94 | A potent, selective Grp94 inhibitor with IC50 of 8 nM. |
|
| DC11619 | KUNG29 | A potent, selective Grp94 inhibitor with Kd of 0.2 uM. |
|
| DC11618 | KUNG38 | A potent, selective Grp94 inhibitor with Kd of 0.44 uM. |
|
| DC11617 | PU-H54 Featured | PU-H54 is potent, selective Grp94 inhibitor. |
|
| DC20400 | HDAC1,2-IN-2 | A potent, selective HDAC1 and HDAC2 inhibitor with IC50 of 6 nM and 45 nM, respectively. |
|
| DC11597 | SB-429201 | A potent, selective HDAC1 inhibitor with IC50 of 1.5 uM. |
|
| DC21373 | HDAC6 inhibitor NCT-14b | A potent, selective HDAC6 inhibitor with IC50 of 84 nM, with IC50s of >3.5 uM for the other HDAC isoforms.. |
|
| DC21461 | PD-118057 | A potent, selective hERG potassium channel (Kv11.1) activator that increases peak tail hERG current of 111.1% at 10 uM in HEK293 cells. |
|
| DC22946 | ML-T531 Featured | ML-T531 is a potent, selective hERG potassium channel (Kv11.1) activator with EC50 of 3.13 uM. |
|
| DC22990 | HIF1-IN-2 | A potent, selective HIF-1 inhibitor with IC50 of 1.9 nM, with no signigicant inhibition on HSF and NF-κB. |
|
| DC25054 | Gambogic amide | A potent, selective high affinity TrkA receptor agonist with Kd of 75 nM. |
|
