| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC22980 | ND-336 | A selective inhibitor of the gelatinases MMP2 and MMP9 and MMP13 with Ki of 85, 150 and 120 nM, respectively. |
|
| DC21127 | HT-0411 | A selective monoamine oxidase B (MAO-B) inhibitor with IC50 of 1.4 uM, with less potency for MT-1 and MT-2. |
|
| DC23235 | Flupirtine | A selective neuronal potassium channel (KCNQ/KV7 channel) activator that also has indirect NMDA receptor antagonist and GABAA receptor modulatory properties. |
|
| DC26069 | SR-11237 Featured | SR-11237 is a selective pan retinoid X receptor (RXR) agonist with no retinoid A receptor (RAR) activity. . |
|
| DC22616 | CJ-42794 Featured | A selective prostaglandin E receptor subtype 4 (EP4) antagonist with pKi of 8.5. |
|
| DC12014 | NSC117079 | A selective protein phosphatase PHLPP inhibitor with IC50 of 4 uM for PP2C domain of PHLPP2. |
|
| DC12013 | NSC45586 Featured | A selective protein phosphatase PHLPP inhibitor with IC50 of 4 uM for PP2C domain of PHLPP2. |
|
| DC11946 | BNBI | A selective renal outer medullary potassium channel (ROMK, Kir1.1) inhibitor with IC50 of 8 uM in T1+ flux assays, does not inhibit Kir7.1 at 100 uM. |
|
| DC20567 | Tec Kinase-IN-21 | A selective small molecule toward Tec kinase-mediated tyrosine phosphorylation of FGF2 with IC50 of 11.7 uM. |
|
| DC20566 | Tec Kinase-IN-14 | A selective small molecule toward Tec kinase-mediated tyrosine phosphorylation of FGF2 with IC50 of 7.0 uM. |
|
| DC25014 | Cysmethynil | A selective small-molecule inhibitor of tisoprenylcysteine carboxyl methyltransferase (Icmt) with IC50 <200 nM, does not inhibit other enzymes (farensyltransferase, geranylgeranyltransferase type I, and Rce1) at concentrations up to 50 uM. |
|
| DC22924 | 3M-002 Featured | A selective TLR8 agonist that induces activation of NF-κB at 0.4 uM. |
|
| DC20306 | AMTB hydrochloride Featured | A selective TRPM8 channel blocker with pEC50 of 6.91 in Ca(2+) influx assay, with no activity for TRPV4 (pEC50<4.6). |
|
| DC23226 | Guanfacine | A selective α2A receptor agonist that can reduce peripheral sympathetic outflow and thus cansues a reduction in peripheral sympathetic tone. |
|
| DC24156 | Metoprolol | A selective β1 receptor blocker used in treatment of several diseases of the cardiovascular system, especially hypertension.. |
|
| DC7029 | SC-26196 Featured | A selective Δ6 desaturase inhibitor that displays selectivity over Δ5 and Δ9 desaturases |
|
| DCAPI1468 | Rosuvastatin Calcium Featured | A selective, competitive inhibitor of HMG-CoA reductase, that is also antilipemic. |
|
| DC26107 | TRV0109101 hydrochloride | A selective, G protein-biased µ-opioid receptor agonist, does not promote the development of opioid-induced mechanical allodynia (OIMA) and rapidly reverses allodynia in vivo.. |
|
| DC26103 | TRV0109101 | A selective, G protein-biased µ-opioid receptor agonist, does not promote the development of opioid-induced mechanical allodynia (OIMA) and rapidly reverses allodynia in vivo.. |
|
| DC11737 | GNF-6702 | A selective, non-competitive inhibitor of the kinetoplastid proteasome, inhibits the chymotrypsin-like activity of the T. cruzi proteasome with IC50 of 35 nM. |
|
| DC21728 | TAK-070 | A selective, nonpeptidic, noncompetitive BACE1 inhibitor with IC50 of 3.15 uM in cell-free assays. |
|
| DC20995 | EP009 | A selective, orally active JAK3 inhibitor that reduces IL-2-mediated JAK3 tyrosine phosphorylation with cellular IC50 of 10-20 uM. |
|
| DC20287 | δ-secretase inhibitor 11 | A selective, orally bioactive and brain permeable δ-secretase (AEP. |
|
| DC12005 | Iberiotoxin | A selective, potent peptidyl blocker of the big conductance Ca2+-activated K+ channel (BKCa, KCa1.1, MaxiK) with IC50 of 0.25 nM. |
|
| DC12006 | Charybdotoxin | A selective, potent peptidyl blocker of the big conductance Ca2+-activated K+ channel (BKCa, KCa1.1, MaxiK). |
|
| DC11884 | Sercloremine hydrochloride | A selective, reversible inhibitor of MAO-A and serotonin reuptake inhibitor as an antidepressant.. |
|
| DC11885 | Sercloremine | A selective, reversible inhibitor of MAO-A and serotonin reuptake inhibitor as an antidepressant.. |
|
| DC22971 | CDE 096 | A selective, reversible, high-affinity PAI-1 inhibitor that prevents PAI-1 from inactivating tPA and uPA with similar potency (IC50=30 and 25 nM, respectively). |
|
| DC21780 | UNC-3230 | A selective, small molecule inhibitor of PIP5K1C with IC50 of 41 nM, does not ihibits other lipid kinases including PI3Ks. |
|
| DC21400 | NS-1209 | A selective, water-soluble, in vivo long-lasting AMPA antagonist with Ki of 43 nM. |
|
