| DC24176 |
Esomeprazole potassium salt |
A proton pump inhibitor that reduces stomach acid secretion by inhibition of the H+/K+-ATPase in the parietal cells. |
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| DC23938 |
Esomeprazole sodium
Featured
|
A proton pump inhibitor that reduces stomach acid secretion by inhibition of the H+/K+-ATPase in the parietal cells. |
|
| DC11545 |
IPAG
Featured
|
IPAG is a prototypic selective inhibitor of sigma1 receptor that engages the unfolded protein response and induces autophagy in cancer cells. |
|
| DC23004 |
PSMA-ligand-1
Featured
|
PSMA ligand-tubulysin compounds represent a cutting-edge approach to targeted cancer therapy, combining the precision of PSMA targeting with the potent cytotoxicity of tubulysin. This strategy holds significant promise for improving outcomes in prostate cancer and other PSMA-expressing malignancies, offering a highly specific and effective treatment option with reduced systemic toxicity. As research progresses, these compounds could play a transformative role in the field of oncology. |
|
| DC20605 |
Enexasogaol |
A pungent agent isolated from Zingiber officinale Roscoe, has been known to have anti-tumor and anti-inflammatory effects. |
|
| DC11949 |
SR-653234 |
A purine scaffold casein kinase 1δ/1ε (CK1δ/ε) inhibitor with IC50 of 160/540 nM, respectively.. |
|
| DC22348 |
Zalcitabine
Featured
|
A pyrimidine analog reverse transcriptase inhibitor (NRTI) for the treatment of HIV/AIDS. |
|
| DC22388 |
Mefloquine hydrochloride |
A quinoline antimalarial drug that is structurally related to the antiarrhythmic agent quinidine. |
|
| DC21407 |
AG-1295 |
A quinoxaline-type tyrphostin that acts as a potent and selective inhibitor of PDGFR kinase in vitro and in Swiss 3T3 cells with IC50 of 0.3-1 uM. |
|
| DC23472 |
TASP0434299 |
A radioligand candidate for arginine vasopressin 1B (V1B) receptor that exhibits high binding affinities for human and rat V1B receptors with IC50 of 0.526 and 0.641 nM, respectively. |
|
| DC26104 |
UVI 2008 |
A RARβ/γ agonist originated from TTNPB, is also a selective inhibitor of aldo-keto reductase family member 1B10 (AKR1B10) with IC50 of 6.1 uM. |
|
| DC22985 |
BMS-948 |
A RARβ-selective agonist that exhibits a full transcriptional agonistic activity and activating RARβ as efficiently as the reference agonist TTNPB. |
|
| DC7350 |
9-methyladenine |
A receptor adenine derivative binding membrane brain animal cell line.For the detailed information of 9-methyladenine, the solubility of 9-methyladenine in water, the solubility of 9-methyladenine in DMSO, the solubility of 9-methyladenine in PBS buffer, the animal experiment (test) of 9-methyladenine, the cell expriment (test) of 9-methyladenine, the in vivo, in vitro and clinical trial test of 9-methyladenine, the EC50, IC50,and Affinity of 9-methyladenine, Please contact DC Chemicals.. |
|
| DC23842 |
L-783277 |
A resorcylic lactone type covalent kinase inhibitor that inhibits ALK1 with IC50 of 125 nM, also inhibits FLT3, VEGFR2, VEGFR3, MEK2 with IC50 of 1-10 nM.. |
|
| DC7054 |
AM580
Featured
|
A retinoic acid analog and selective RARα agonist |
|
| DC24096 |
Dabigatran ethyl ester |
A reversible and selective, direct thrombin inhibitor (DTI) with Ki value of 4.5 nM. |
|
| DC11918 |
CMLD010509 |
A rocaglate (flavagline) derivative that acts a highly specific inhibitor of the oncogenic translation program supporting MM, including key oncoproteins such as MYC, MDM2, CCND1, MAF, and MCL-1. |
|
| DC22367 |
Bromethalin |
A rodenticide that poisons the central nervous system by uncoupling mitochondrial oxidative phosphorylation, which causes a decrease in adenosine triphosphate (ATP) synthesis.. |
|
| DC21011 |
KP-1019 sodium salt |
A ruthenium complex anticancer agent that is useful for metastatic tumors and cis-platin resistant tumors. |
|
| DC20822 |
BMT-052 |
A second generation, orally biovailable pan-genotypic HCV NS5B polymerase inhibitor with EC50 of 1-10 nM. |
|
| DC24180 |
Cetirizine |
A second-generation antihistamine that acts as a selective H1 receptor antagonist. |
|
| DC22589 |
Eltanexor |
A second-generation SINE, orally bioavailable Exportin 1 (XPO1,CRM1) inhibitor with markedly reduced brain penetration compared to selinexor (30-fold less). |
|
| DC23944 |
K-7174
Featured
|
A selctive small molecule inhibitor of the transcription factor GATA-binding protein 2 (GATA2). |
|
| DC23943 |
K-7174 dihydrochloride
Featured
|
K-7174 dihydrochloride is a selctive small molecule inhibitor of the transcription factor GATA-binding protein 2 (GATA2). |
|
| DC20568 |
Tec Kinase-IN-6 |
A selecitve small molecule toward Tec kinase-mediated tyrosine phosphorylation of FGF2 with IC50 of 8.9 uM. |
|
| DC23996 |
Capadenoson
Featured
|
Capadenoson is a selective agonist of adenosine-A1 receptor. |
|
| DC22954 |
MG-624
Featured
|
MG624 is a potent and selective neuronal α7 nAChR antagonist with a Ki of 106 nM. |
|
| DC21853 |
Ogerin
Featured
|
A selective GPR68 positive allosteric modulator (pEC50=6.83) with minimal PAM activity at the related proton-sensing GPCRs GPR4 and GPR65. |
|
| DC20596 |
O-phenanthroline |
A selective inhibitor of 26S proteasome subunit Rpn11 with IC50 of 10±2 uM. |
|
| DC22980 |
ND-336 |
A selective inhibitor of the gelatinases MMP2 and MMP9 and MMP13 with Ki of 85, 150 and 120 nM, respectively. |
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