DC22546 |
Antibiotic-5d |
A synthetic antimicrobial compound that antibacterial activity in vitro against various Gram-positive and Gram-negative bacteria, fungi and yeast.. |
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DC23906 |
Butenafine hydrochloride
Featured
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A synthetic benzylamine antifungal that inhibits the synthesis of ergosterol by inhibiting squalene epoxidase. |
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DC20656 |
AM-2201 |
A synthetic cannabinoid that acts as a potent, nonselective full agonist for the cannabinoid receptor with EC50 of 38 and 58 nM for CB1 and CB2, respectively. |
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DC23209 |
HO-3867
Featured
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A synthetic curcuminoid that selectively inhibits STAT3 phosphorylation, transcription, and DNA binding without affecting the expression of other active STATs. |
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DC11517 |
Benzodrocortisone |
A synthetic glucocorticoid corticosteroid.. |
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DC11525 |
Mocravimod |
A synthetic immunosuppressant that functions as a S1P1 receptor agonist. |
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DC23705 |
Lenabasum |
A synthetic nonpsychoactive cannabinoid acid with potent analgesic and anti-inflammatory activity in vivo, binds directly and selectively to PPARγ. |
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DC22494 |
ST-2825 |
A synthetic peptido-mimetic compound that inhibits MyD88 dimerization in a TIR-dependent manner. |
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DC22357 |
Benfotiamine |
A synthetic S-acyl derivative of thiamine (vitamin B1) that possesses anti-inflammatory effects. |
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DC22458 |
RX-055 |
A tailored WOBE437-derived diazirine-containing photoaffinity probe that irreversibly blocks membrane transport of both endocannabinoids. |
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DC22474 |
Demeclocycline hydrochloride |
A tetracycline antibiotic that acts by binding to the 30S ribosomal subunit to inhibit binding of aminoacyl tRNA which impairs protein synthesis by bacteria. |
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DC23965 |
Clopidogrel thiolactone
Featured
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A thienopyridine-class antiplatelet agent that works by irreversibly inhibiting P2Y12 receptor on platelets. |
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DC7517 |
THIACETAZONE
Featured
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A thiosemicarbazone that is used in association with other antimycobacterial agents in the initial and continuation phases of antituberculosis regimens. Thiacetazone containing regimens are less effective than the short-course regimen recommended by the I |
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DC25059 |
BMS-986001 |
A thymidine analogue nucleoside reverse transcriptase inhibitor (NRTI) that inhibits HIV-2 isolates from treatment-naive individuals with EC50 of 30-81 nM. |
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DC9633 |
Toll-like receptor modulator |
A Toll-like receptor modulator. |
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DC24097 |
Ufenamate |
A topical analgesic that possesses anti-inflammatory effect for treatment of skin diseases, such as acute and chronic eczema, contact dermatitis, diaper dermatitis, miliaria and atopic dermatitis.. |
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DC22457 |
NAPQI
Featured
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A toxic byproduct, iminoquinone metabolite of acetaminophen that covalently binds to the active site of MIF. |
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DC24092 |
Posaconazole hydrate
Featured
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A triazole antifungal agent that blocks the synthesis of ergosterol by inhibiting of the enzyme lanosterol 14α-demethylase and accumulation of methylated sterol precursors, more potent at inhibiting 14α-demethylase than itraconazole.. |
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DC21517 |
Mithramycin A |
A tricyclic pentaglycosidic, antineoplastic antibiotic from Streptomyces strains that inhibits RNA and protein synthesis by adhering to DNA. |
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DC21638 |
SLV peptide |
A tripeptide representing the Fas-C terminus that specifically blocks the interaction of Fap1 with Fas. |
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DC24136 |
Amitifadine hydrochloride |
A triple monoamine reuptake inhibitor that inhibits the reuptake of [3H]serotonin, [3H]norepinephrine, and [3H]dopamine in HEK 293 cells expressing the corresponding human recombinant transporters (IC50 values of 12, 23, and 96 nM, respectively). |
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DC22736 |
Amitifadine |
A triple monoamine reuptake inhibitor, inhibits the reuptake of 5-HT, norepinephrine and dopamine in HEK 293 cells with IC50 of 12, 23 and 96 nM, respectively. |
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DC21185 |
Cucurbitacin I |
A triterpenoid compound that potently and selectively inhibits JAK/STAT3 pathway, suppresses the levels of phosphotyrosine STAT3 in A549 cell with IC50 of 500 nM. |
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DC23062 |
RAMX3 |
A tritium-labeled allosteric modulator of the human chemokine receptor CXCR3 with Kd of 1.08 nM. |
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DC22473 |
Loxapine |
A typical antipsychotic agent that displays an extremely strong binding affinity for dopamine D4 and serotonin 5-HT2 receptors.. |
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DC22477 |
Loxapine succinate |
A typical antipsychotic agent that displays an extremely strong binding affinity for dopamine D4 and serotonin 5-HT2 receptors.. |
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DC8197 |
Tyrosine kinase inhibitor
Featured
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A Tyrosine kinase inhibitor. |
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DC22811 |
TX-1123 |
A tyrphostin AG17 analog that exihibits potent Src-K inhibitory activity with IC50 of 2.2 uM. |
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DC24189 |
Closantel sodium |
A veterinary anthelmintic with known proton ionophore activities. |
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DC24190 |
Closantel |
A veterinary anthelmintic with known proton ionophore activities. |
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