| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC11578 | VHL Ligand 3 Featured | A VHL ligand for PROTAC.. |
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| DC11581 | VHL Ligand 4 | A VHL ligand for PROTAC.. |
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| DC11580 | VHL-2 | A VHL ligand for PROTAC.. |
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| DC23096 | BCX-4430 | A viral RNA-dependent RNA polymerase (RdRp) inhibitor that acts as a non-obligate RNA chain terminator. |
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| DC25095 | BCX4430 freebase | A viral RNA-dependent RNA polymerase (RdRp) inhibitor that acts as a non-obligate RNA chain terminator. |
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| DC22579 | Retaspimycin hydrochloride | A water-soluble derivative of 17-AAG and HSP90 inhibitor. |
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| DC22983 | Minnelide | A water-soluble prodrug of triptolide that is highly effective in reducing pancreatic tumor growth and spread, and improving survival. |
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| DC22868 | Propofol | A widely used general anesthetic to induce and maintain anesthesia. |
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| DC23233 | AH 6809 Featured | A xanthone derivative that fuctions as an EP and DP receptor antagonist. |
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| DC22878 | LB-205 | A Zn2+-dependent pan-inhibitor of class I and class II HDACs with a long half-life (12h) in vivo. |
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| DC11491 | A-1048400 | A-1048400(A 1048400) is a novel potent, selective, orally active N-type and T-type calcium channel blocker with IC50 of 1.4 and 1.2 uM, respectively. |
|
| DC9768 | A1155463 Featured | A-1155463 is a highly potent and selective BCL-XL inhibitor. |
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| DC8475 | A-1210477 Featured | A-1210477 is a potent and selective MCL-1 inhibitor. |
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| DC10920 | A12B4C3 | A12B4C3 (hPNKP inhibitor A12B4C3) is a specific, noncompetitive inhibitor of the human DNA repair enzyme polynucleotide kinase/phosphatase (hPNKP) with C50 of 60 nM, displays no inhibition of calcineurin and protein phosphatase-1 or APTX. |
|
| DC9296 | A-1331852 Featured | A-1331852 is a high affinity BH3 mimetic Ligand of BCL protein BCL-XL. |
|
| DC12702 | A1874 Featured | A1874 (A-1874) is a nutlin-based and BRD4-degrading PROTAC with DC50 of 32 nM (induce BRD4 degradation in cells). |
|
| DC10509 | A-196 Featured | A-196 is a potent and selective chemical inhibitor of SUV420H1 and SUV420H2 that inhibits the di- and trimethylation of H4K20me in multiple cell lines. |
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| DC7044 | A-205804 | A-205804 is a potent and selective inhibitor of E-selectin and ICAM-1 expression with IC50 of 20 nM and 25 nM respectively. |
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| DC9574 | A-317491 (sodium salt hydrate) Featured | A-317491 is a non-nucleotide P2X3 and P2X2/3 receptor antagonist, which inhibits calcium flux mediated by the receptors. |
|
| DC11490 | A-317567 | A-317567 (A317567) is a novel potent acid sensing ion channel (ASIC) blocker with IC50 of 2-30 uM. |
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| DC23659 | A-357300 | A-357300 is a potent, selective, reversible MetAP2 inhibitor with IC50 of 0.12 uM, does not inhibit MetAP1 or leucine aminopeptidases at 10 uM. |
|
| DC7855 | A-366 Featured | A-366 is a potent and selective G9a/GLP histone lysine methyltransferase inhibitor (IC50 = 3.3 nM). |
|
| DC12659 | A-381393 Featured | A-381393 is a potent and selective agonist of the dopamine D4 receptor. |
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| DC10129 | A395 Featured | A-395 potently inhibited the formation of H3K27me3 (via antagonizing EED in the trimeric PRC2 complex (EZH2:EED:SUZ12)) with IC50 = 34 ± 2 nM (Hill Slope = 0.7) |
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| DC20610 | A-395N | A-395N is the negative control compound of A-395, which is a potent, selective, and cellularly active PRC2 subunit EED inhibitor with Kd of 1.5 nM.. |
|
| DC22277 | A-420983 Featured | A-420983 is a potent, orally active inhibitor of lck with efficacy in a model of transplant rejection. |
|
| DC20611 | A4250 Featured | A4250 (A-4250, Odevixibat) is a small molecule ileal bile acid transporter (IBAT) inhibitor for the treatment of cholestatic liver diseases including progressive familial intrahepatic cholestasis and NASH.. |
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| DC8406 | A-438079 HCl Featured | A-438079 HCl is a potent, and selective P2X7 receptor antagonist with pIC50 of 6.9. |
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| DC12317 | A-484954 | A-484954 is a highly selective eukaryotic elongationfactor-2 (eEF2) inhibitor, with an IC50 of 280 nM. |
|
| DC7538 | A66 Featured | A66 is a potent and specific p110α inhibitor with IC50 of 32 nM, >100 fold selectivity for p110α over other class-I PI3K isoforms. |
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