| DC8358 |
ONO-4059(Tirabrutinib)
Featured
|
ONO-4059 is a novel Small Molecule Dual Inhibitor Of Bruton’s Tyrosine Kinase (Btk) and Tec Kinase. |
|
| DC11905 |
Opiranserin
Featured
|
Opiranserin (VVZ-149, VVZ-000149) is a potent, selective, mixed glycine GlyT2 transporter blocker (IC50= 0.86 uM), purine P2X3 receptor antagonist (IC50=0.87 uM) and serotonin 5-HT2A receptor antagonist (IC50=1.3 uM). |
|
| DC2010 |
Oprozomib (ONX-0912)
Featured
|
Oprozomib (ONX 0912) selectively inhibits CT-L activity of 20S proteasome β5/LMP7 with IC50 of 36 nM/82 nM. |
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|
| DC10394 |
Org-26576 |
Org 26576 is a AMPA receptor positive allosteric modulator. |
|
| DC11203 |
ORIC-101
Featured
|
ORIC-101 (ORIC101) is a highly potent, selective steroidal glucocorticoid receptor (GR) antagonist (IC50=5.6 nM) with reduced androgen receptor (AR) agonistic activity. |
|
| DC23149 |
Oseltamivir acid |
Oseltamivir acid (GS 4071, Ro 64-0802, Oseltamivir carboxylate) is a potent inhibitor of influenza neuraminidase (NA) with Ki of <1 nM for both A and B strains,showed potent activity against COVID-19(SARS-COV-2). |
|
| DCAPI1594 |
Oseltamivir phosphate
Featured
|
OSELTAMIVIR is an active (orally) inhibitor of the influenze virus neuraminidase and converted to the active acid metabolite in vivo. |
|
| DC1006 |
OSI-027
Featured
|
OSI-027 is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM, respectively. |
|
| DC4105 |
Linsitinib(OSI-906)
Featured
|
OSI-906 (Linsitinib) is a selective inhibitor of IGF-1R and IR with IC50 of 35 nM and 75 nM, respectively. |
|
| DC7219 |
OSI 930
Featured
|
OSI-930 is a potent inhibitor of Kit, KDR and CSF-1R with IC50 of 80 nM, 9 nM and 15 nM, respectively; also potent to Flt-1, c-Raf and Lck and low activity against PDGFRα/β, Flt-3 and Abl. |
|
| DC8248 |
Ostarine(MK-2286)
Featured
|
Ostarine (MK-2866) is a selective androgen receptor modulator (SARMs) that regulates cardiomyocyte function, improves bone healing, regulates uterine function, and influences muscle tissue metabolism. |
|
| DC7220 |
OSU-03012
Featured
|
OSU-03012(AR-12) is a potent inhibitor of recombinant PDK-1 with IC50 of 5 μM and 2-fold increase in potency over OSU-02067. |
|
| DC9443 |
Otamixaban |
Otamixaban(FXV673) is a potent (Ki = 0.5 nM), selective, rapid acting, competitive and reversible fXa inhibitor that effectively inhibits both free and prothrombinase-bound fXa.
|
|
| DC7109 |
Otenabant (CP-945598 free base)
Featured
|
Otenabant (CP945598) is a recently discovered selective, high affinity, competitive CB1 receptor antagonist with Ki of 0.7 nM. |
|
| DC8732 |
OTSSP167
Featured
|
OTSSP167 is a highly potent MELK inhibitor (IC50 = 0.41 nM) and inhibited the phosphorylation of PSMA1 (proteasome subunit alpha type 1) and DBNL (drebrin-like). |
|
| DC7475 |
OTSSP167 HCl
Featured
|
OTSSP167 is a highly potent MELK inhibitor (IC50 = 0.41 nM) and inhibited the phosphorylation of PSMA1 (proteasome subunit alpha type 1) and DBNL (drebrin-like). |
|
| DC5885 |
Oxaliplatin
Featured
|
Oxaliplatin is a second generation potent platinum-based anti-neoplastic agent that is believed to form inter- and intrastrand DNA adducts which activate signaling pathways culminating in apoptosis. The development of Oxaliplatin was inspired from the eff |
|
| DC8281 |
Ozanimod (RPC1063)
Featured
|
Ozanimod (RPC1063) is a selective S1P1R modulator |
|
| DC10399 |
PAC-14028 |
PAC-14028 is a potent and selective transient receptor potential vanilloid type I (TRPV1) antagonist. |
|
| DC11113 |
Padsevonil |
Padsevonil (UCB-0942, UCB0942) is a potential anti-seizure agent that functions as a pre- and post-synaptic inhibitor.. |
|
| DC10292 |
Pagoclone |
Pagoclone is an active (+)-enantiomer of the racemate RP 59037. Pagoclone is a partial GABA(A) receptor agonist used for the treatment of panic and anxiety disorders. |
|
| DC8717 |
PAK4-IN-1（KPT9274）
Featured
|
PAK4-IN-1 is an inhibitor of p21-activated kinases (PAKs), with IC50 of ≤100 nM in MTT assay. |
|
| DC8469 |
Palbociclib
Featured
|
Palbociclib (PD-0332991) is an orally available pyridopyrimidine-derived cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity. |
|
| DC5067 |
Palbociclib (PD0332991 HCl)
Featured
|
Palbociclib is an oral, small molecule cyclin-dependent kinase 4/6 (CDK4/6) inhibitor, now in Phase 3 clinical development for advanced breast cancer. |
|
| DC7970 |
ACT058362 (Palosuran)
Featured
|
Palosuran (ACT-058362) is a new potent and specific antagonist of the human UT receptor with an IC50 of 3.6±0.2 nM. |
|
| DC9681 |
Pamapimod（R-1503）
Featured
|
Pamapimod（R-1503）is a novel p38 MAP kinase inhibitor. |
|
| DC7183 |
Panobinostat(LBH589)
Featured
|
Panobinostat(LBH-589) is a broad-spectrum HDAC inhibitor; low nanomolar concentrations (IC50=5-20 nM) of LBH589 induced cell-cycle arrest, apoptosis, and histone (H3K9 and H4K8) hyperacetylation in MOLT-4 and Reh cell. |
|
| DC9876 |
Pantoprazole |
Pantoprazole is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease. |
|
| DC9135 |
Pantoprazole Sodium |
Pantoprazole sodium salt(SKF96022; Protonix) is a proton pump inhibitor drug used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease. |
|
| DC10255 |
Parecoxib |
Parecoxib is a selective COX2 inhibitor. |
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