| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC9520 | NKP608 | NKP608 is a non-peptidic derivative of 4-aminopiperidine which acts as a selective, specific and potent antagonist at the neurokinin-1 (NK-1) receptor both in vitro(IC50=2.6 nM) and in vivo. |
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| DC8021 | Indoximod (NLG-8189) Featured | NLG-8189 is an inhibitor of IDO and INDOL1 (IDO2) |
|
| DC9936 | NMS-P118 Featured | NMS-P118 is a potent, orally available, and highly selective PARP-1 inhibitor with excellent ADME and pharmacokinetic profiles and high efficacy in vivo. |
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| DC8178 | Beclabuvir(BMS-791325) | non-nucleoside inhibitor of the NS5B |
|
| DC8583 | Asenapine Maleate Featured | Novel psychopharmacologic agent. Displays antagonist activity at 5-HT, dopamine, noradrenalin and histamine receptor subtypes (pKi values are 8.60, 8.40, 10.15, 9.75, 10.46, 8.84, 9.60, 9.94, 8.85, 8.90, 8.84, 9.38, 8.95, 8.93, 8.9, 9.49, 8.91, 9.00 and 8 |
|
| DC4136 | NPS-2143 HCL | NPS 2143 hydrochloride is a selective CaSR (Ca2+-sensing receptor) inhibitor and antagonist, shown to block increases in cytoplasmic Ca2+ concentrations elicited by human Ca2+ receptors expressed in HEK293 cells with an IC50 of 43 nM. NPS 2143 hydrochlori |
|
| DC7214 | NPS-2143(SB 262470A ) | NPS-2143(SB 262470A ) is a selective potent calcium ion-sensing receptor antagonist with IC50 of 43 and 41 nM for cytoplasmic Ca2+ concentrations and parathyroid hormone secretion, respectively. |
|
| DC8183 | Paritaprevir(Veruprevir ABT-450) Featured | NS3/4A protease inhibitor |
|
| DC9486 | Nucleozin Featured | Nucleozin targets influenza A nucleoprotein (NP), a multifunctional, RNA-binding protein necessary for virus replication. |
|
| DC4174 | NVP-AEW541 Featured | NVP-AEW541 is a potent inhibitor of IGF-1R with IC50 of 86 nM. |
|
| DC4118 | NVP-BEP800 Featured | NVP-BEP800 is a novel, fully synthetic HSP90β inhibitor with IC50 of 58 nM. |
|
| DC3133 | NVP-BGT226 (BGT226） Featured | NVP-BGT226 is a novel dual PI3K/mTOR inhibitor with IC50 of 1 nM. |
|
| DC7303 | NVP-TAE684 Featured | NVP-TAE684(TAE684) is a highly potent and selective small-molecule ALK inhibitor, which blocked the growth of ALCL-derived and ALK-dependent cell lines with IC50 values between 2 and 10 nM. |
|
| DC4237 | NXY-059 (Cerovive) | NXY-059 (Cerovive) is an EGFR and HER2 autophosphorylation inhibitor, against purified EGFR and HER2 of 10.2 and 9.8 nM, respectively. |
|
| DC10807 | O304 Featured | O304 is a novel AMPK activator. |
|
| DC10134 | Obicetrapib (AMG-899,TA-8995) Featured | Obicetrapib is a CETP inhibitor, on the elevation of high-density lipoprotein cholesterol (HDL-C) and reduction of low-density lipoprotein cholesterol (LDL-C), alone and in combination with statin therapy. |
|
| DC12298 | Octreotide acetate (SMS 201-995 (acetate)) Featured | Octreotide acetate, a long-acting synthetic analog of native somatostatin, inhibits growth hormone, glucagon, and insulin more potently. |
|
| DC6401 | Odanacatib (MK 0822) Featured | Odanacatib (MK 0822) is a potent, selective, and neutral inhibitor of human and rabbit cathepsin K with IC50 of 0.2 nM and 1 nM , respectively. |
|
| DC8700 | ODM-201(Darolutamide) Featured | ODM-201 is a potent and full antagonists for human AR (hAR) with IC50 values of 26 nM by transactivation assays in AR-HEK293 cells. |
|
| DC9583 | Oglemilast Featured | Oglemilast(GRC3886) is a potent PDE4 inhibitor, under clinical studies in the treatment of allergen-induced asthma. |
|
| DC11096 | Olacaftor | Olacaftor (VX-440, VX440) is a next-generation CFTR corrector, showsthe potential to enhance the amount of CFTR protein at the cell’s surface and for treatment of cystic fibrosis.. |
|
| DC4110 | AZD-2281 (Olaparib) Featured | Olaparib (AZD2281, KU0059436) is a selective inhibitor of PARP1 and PARP2 with IC50 of 5 nM and 1 nM, respectively. |
|
| DCAPI1464 | Olmesartan | Olmesartan Acid is an angiotensin II receptor antagonist that prevents the binding of angiotensin II, thus preventing vasoconstriction. |
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| DC9179 | Olmesartan MedoxoMil | Olmesartan medoxomil(Olmetec; Benicar; CS 866) is an angiotensin II receptor antagonist which is used as an anti-hypertensive. |
|
| DC10384 | Olodaterol Featured | Olodaterol (BI1744) is a long acting β2-adrenoceptor agonist with an EC50 of 1.4±0.08 nM. |
|
| DC9248 | Olodaterol(BI-1744) hydrochloride Featured | Olodaterol is a novel, long-acting beta2-adrenergic agonist (LABA) that exerts its pharmacological effect by binding and activating beta2-adrenergic receptors located primarily in the lungs. |
|
| DC8390 | Oltipraz Featured | Oltipraz is a potent Nrf2 activator and a potent inducer of Phase II detoxification enzymes, most notably glutathione-S-transferase (GST). Phase 3. |
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| DC10299 | Olumacostat glasaretil | Olumacostat glasaretil is a small molecule inhibitor of acetyl coenzyme A carboxylase (ACC). |
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| DC12281 | Olutasidenib (FT-2102) Featured | Olutasidenib is a highly potent, selective inhibitor of mutant Isocitrate dehydrogenase (IDH)1 that could be used in the treatment of acute myeloid leukemia. |
|
| DC10324 | Omapatrilat | Omapatrilat is a dual inhibitor of the metalloproteases ACE and NEP with Ki values of 0.64 and 0.45 nM, respectively. |
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