Cat. No. | Product name | CAS No. |
DC7902 |
Fruquintinib (HMPL-013)
Featured
Fruquintinib (HMPL-013) is a novel small molecule compound that selectively inhibits vascular endothelial growth factor receptors (VEGFRs). |
1194506-26-7 |
DC11776 |
G-744
G-744 is a highly potent, selective inhibitor of BTK with biochemical Ki of 1.28 nM. |
1346669-54-2 |
DC7792 |
G-749
Featured
G-749 is an inhibitor of Fms-like tyrosine receptor kinase 3 (FLT3) with IC50 values ranging from 2.1 to 38.1 nM for wild-type and mutant (constitutively active) FLT3s in Ba/F3 cells expressing recombinant receptors. |
1457983-28-6 |
DC9942 |
GDC-0853(RG7845)
Featured
GDC-0853 is orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity. |
1434048-34-6 |
DC2103 |
Gefitinib (ZD1839)
Featured
Gefitinib (Iressa, ZD-1839) is an EGFR inhibitor for Tyr1173, Tyr992, Tyr1173 and Tyr992 in the NR6wtEGFR and NR6W cells with IC50 of 37 nM, 37nM, 26 nM and 57 nM, respectively. |
184475-35-2 |
DC11543 |
Glumetinib
Featured
Glumetinib (SCC 244) is a novel potent and highly selective inhibitor of c-Met kinase with IC50 of 0.42 nM. |
1642581-63-2 |
DC1062 |
GNF-2
Featured
GNF-2 is a highly selective non-ATP competitive inhibitor of Bcr-Abl, inhibiting the proliferation of the Bcr-Abl-expressing cells with IC50 of 138 nM. |
778270-11-4 |
DC9285 |
GNF-7
Featured
GNF-7 is a potent type-II kinase Bcr-Abl inhibitor with IC50 of <5 nM, 61 nM, 122 nM, 136 nM, and 133 nM for M351T, T315I, E255 V, G250E, and c-Abl, respectively. |
839706-07-9 |
DC2069 |
IGF-1R inhibitor GS1904529A
GSK1904529A is a selective inhibitor of IGF-1R and IR with IC50 of 27 nM and 25 nM, respectively. |
1089283-49-7 |
DC8331 |
GSK2256098
Featured
GSK2256098 is small molecule FAK kinase inhibitor. |
1224887-10-8 |
DC10936 |
GSK3179106
Featured
GSK3179106 (GSK-3179106, GSK 3179106) is a potent, selective, first-in-class and gut-restricted with IC50 of 0.4 and 11 nM in the biochemical assay and cellular assay respectively. |
1627856-64-7 |
DC7145 |
GW441756
Featured
GW 441756 is a specific Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 value of 2 nM; little activity to c-Raf1 and CDK2. |
504433-23-2 |
DC1018 |
GW-2580 (GW2580)
Featured
GW2580 is a selective inhibitor of human c-FMS with IC50 of 30 nM. |
870483-87-7 |
DC10033 |
H3B-6527
Featured
H3B-6527 is an orally bioavailable inhibitor of human fibroblast growth factor receptor 4 (FGFR4), with potential antineoplastic activity. |
1702259-66-2 |
DC10596 |
Lavendustin C (HDBA)
Featured
HDBA, a derivative of a Streptomyces griseolavendus butyl acetate extract, is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase with an IC50 value of 0.012 µM. |
125697-93-0 |
DC11366 |
HKI 357
HKI 357 is an irreversible dual inhibitor of the EGF receptor tyrosine kinases EGFR and HER2 (IC50s = 34 and 33 nM, respectively). |
848133-17-5 |
DC8819 |
Olmutinib (HM61713; BI-1482694)
Featured
HM-61713 (BI-1482694) is an orally available small molecule, mutant-selective inhibitor of epidermal growth factor receptor (EGFR) with potential antineoplastic activity. |
1353550-13-6 |
DC12259 |
HS-10296 hydrochloride
HS-10296 hydrochloride is an orally available and third-Generation inhibitor of epidermal growth factor receptor (EGFR)-activating mutations and T790M-resistant mutation with limited activity against wild-type EGFR. |
2134096-03-8 |
DC12494 |
HS-10296
Featured
HS-10296 is an orally available inhibitor of the epidermal growth factor receptor (EGFR) mutant form T790M, with potential antineoplastic activity. |
1899921-05-1 |
DC8817 |
Icotinib Hydrochloride
Featured
Icotinib is a potent and specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) with an IC(50) of 5 nM, including it's mutants of EGFR(L858R), EGFR(L861Q), EGFR(T790M) and EGFR(T790M, L858R). |
1204313-51-8 |
DC7427 |
Icotinib
Icotinib(BPI-2009) is a potent and specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) with an IC(50) of 5 nM, including it's mutants of EGFR(L858R), EGFR(L861Q), EGFR(T790M) and EGFR(T790M, L858R). |
610798-31-7 |
DC4181 |
Imatinib mesylate
Featured
Imatinib Mesylate is orally bioavailability mesylate salt of Imatinib, which is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM, respectively. |
220127-57-1 |