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AhR modulator-1

  Cat. No.:  DC28914   Featured
Chemical Structure
118174-38-2
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More than 5000 active chemicals with high quality for research!
Field of application
AhR modulator-1 (compound 6-MCDF) is a selective and orally active aryl hydrocarbon receptor (AhR) modulator. AhR modulator-1 inhibits metastasis, in part, by inhibiting prostatic VEGF production prior to tumor formation. AhR modulator-1 also possess anti-estrogenic properties in rat uterus.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 118174-38-2
Chemical Name: Dibenzofuran,1,3,8-trichloro-6-methyl-
Synonyms: Dibenzofuran,1,3,8-trichloro-6-methyl-
SMILES: ClC1=CC(Cl)=C2C3C=C(Cl)C=C(C)C=3OC2=C1
Formula: C13H7Cl3O
M.Wt: 285.55308
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
TITLE DOWNLOAD
MSDS_12965_DC28914_115039-00-4
COA
LOT NO. DOWNLOAD
Cat. No. Product name Field of application
DC28934 VAF347 VAF347 is a cell permeable and highly affinity aryl hydrocarbon receptor (AhR) agonist and induces AhR signaling. VAF347 inhibits the development of CD14+CD11b+ monocytes from granulo-monocytic (GM stage) precursors. VAF347 has anti-inflammatory effects.
DC28914 AhR modulator-1 AhR modulator-1 (compound 6-MCDF) is a selective and orally active aryl hydrocarbon receptor (AhR) modulator. AhR modulator-1 inhibits metastasis, in part, by inhibiting prostatic VEGF production prior to tumor formation. AhR modulator-1 also possess anti-estrogenic properties in rat uterus.
DC11794 GNF-351 GNF-351 is a potent, pure aryl hydrocarbon receptor (AHR) antagonist (IC50=62 nM) devoid of partial agonist potential; antagonizes agonist and SAhRM-mediated suppression of SAA1, inhibit both DRE-dependent and -independent activity; decreases migration and invasion of HNSCC cells and prevents benzo[a]pyrene-mediated induction of the chemotherapy efflux protein ABCG2.
DC11530 Tapinarof (Benvitimod; GSK2894512) Tapinarof (WBI-1001) is a natural aryl hydrocarbon receptor (AhR) agonist with an EC50 of 13 nM. Tapinarof resolves skin inflammation in mice.
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