Cas No.: | 38136-70-8 |
Chemical Name: | Brevianamide F |
Synonyms: | (3S,8aS)-3-(1H-indol-3-ylmethyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione;(3S,8aS)-3-(1H-indol-3-ylmethyl)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione;Brevianamide F;Cyclo(L-Pro-L-Trp);Cyclo(L-Pro-L-Trp-);Cyclo-L-tryptophyl-L-proline;L-Prolyl-L-tryptophan anhydride;Prolyltryptophanyldiketopiperazine;cyclo-L-Prolyl-L-tryptophanyl;(3S,8aS)-Hexahydro-3-(1H-indol-3-ylmethyl)pyrrolo[1,2-a]pyrazine-1,4-dione;Cyclo-L-Trp-L-Pro;cyclo-(Trp-Pro);cyclo-L-tryptophanyl-L-proline;tryptophan-proline diketopiperazine;L-tryptophyl-L-proline cyclic anhydride;AK169895;Cyclo(L-Trp-L-Pro);cyclo-(L-Trp-L-Pro);cyclo-L-proline-L-pryptophan;cyclo-L-pryptophan-L;cyclo-L-pryptophan-L-proline |
SMILES: | O=C1[C@]([H])(C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C([H])C([H])=C23)N([H])C([C@]2([H])C([H])([H])C([H])([H])C([H])([H])N21)=O |
Formula: | C16H17N3O2 |
M.Wt: | 283.3251 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | Brevianamide F , also known as cyclo-(L-Trp-L-Pro), belongs to a class of naturally occurring 2,5-diketopiperazines.Brevianamide F possess interesting breast cancer resistance protein inhibitory activity.[1] brevianamide F once used as aromatic substrate. [2] |
References: | [1]. Wauters I et al. Beyond the Diketopiperazine Family with Alternatively Bridged Brevianamide F Analogues. J Org Chem, 2015 Aug 21, 80(16):8046-54. [2]. Yin S et al. Identification of a brevianamide F reverse prenyltransferase BrePT from Aspergillus versicolor with a broad substrate specificity towards tryptophan-containing cyclic dipeptides. Appl Microbiol Biotechnol, 2013 Feb, 97(4):1649-60. |