UR-MB108|CAS 2412461-98-2|DC Chemicals

Cas No.:	2412461-98-2
Chemical Name:	UR-MB108
Synonyms:	2-Quinolinecarboxamide, N-[5-[1-[4-[2-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]-1H-1,2,3-triazol-4-yl]-2-(1-oxopropyl)phenyl]-
SMILES:	N1C2C(=CC=CC=2)C=CC=1C(NC1=CC(C2=CN(C3=CC=C(CCN4CCC5=C(C4)C=C(OC)C(OC)=C5)C=C3)N=N2)=CC=C1C(=O)CC)=O
Formula:	C₄₀H₃₈N₆O₄
M.Wt:	666.767529010773
Purity:	98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

MSDS

COA

Cat. No.	Product name	Field of application
DC71359	UR-MB108	UR-MB108 (Compound 57) is a potent, selective ABCG2 (BCRP) inhibitor with an IC50 of 79 nM. UR-MB108 is stable in blood plasma.
DC9369	YHO-13177	YHO-13177 is a potent and specific inhibitor of BCRP; potentiated the cytotoxicity of SN-38 in cancer cells and no effect on P-glycoprotein–mediated paclitaxel resistance in MDR1-transduced human leukemia K562 cells.
DC9256	KS176	KS176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter (IC50 values are 0.59 and 1.39 μM in Pheo A and Hoechst 33342 assays respectively). Displays no inhibitory activity against P-gp or MRP1.
DC10605	Brevianamide F	Brevianamide F , also known as cyclo-(L-Trp-L-Pro), belongs to a class of naturally occurring 2,5-diketopiperazines.