UR-MB108

  Cat. No.:  DC71359   Featured
Chemical Structure
2412461-98-2
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More than 5000 active chemicals with high quality for research!
Field of application
UR-MB108 (Compound 57) is a potent, selective ABCG2 (BCRP) inhibitor with an IC50 of 79 nM. UR-MB108 is stable in blood plasma.
Cas No.: 2412461-98-2
Chemical Name: UR-MB108
Synonyms: 2-Quinolinecarboxamide, N-[5-[1-[4-[2-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]-1H-1,2,3-triazol-4-yl]-2-(1-oxopropyl)phenyl]-
SMILES: N1C2C(=CC=CC=2)C=CC=1C(NC1=CC(C2=CN(C3=CC=C(CCN4CCC5=C(C4)C=C(OC)C(OC)=C5)C=C3)N=N2)=CC=C1C(=O)CC)=O
Formula: C40H38N6O4
M.Wt: 666.767529010773
Purity: 98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC71359 UR-MB108 UR-MB108 (Compound 57) is a potent, selective ABCG2 (BCRP) inhibitor with an IC50 of 79 nM. UR-MB108 is stable in blood plasma.
DC9369 YHO-13177 YHO-13177 is a potent and specific inhibitor of BCRP; potentiated the cytotoxicity of SN-38 in cancer cells and no effect on P-glycoprotein–mediated paclitaxel resistance in MDR1-transduced human leukemia K562 cells.
DC9256 KS176 KS176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter (IC50 values are 0.59 and 1.39 μM in Pheo A and Hoechst 33342 assays respectively). Displays no inhibitory activity against P-gp or MRP1.
DC10605 Brevianamide F Brevianamide F , also known as cyclo-(L-Trp-L-Pro), belongs to a class of naturally occurring 2,5-diketopiperazines.
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