KS176|cas 1253452-78-6|DC Chemicals

Cas No.:	1253452-78-6
Chemical Name:	KS 176
Synonyms:	KS 176;KS-176;N-[4-(2-Hydroxyethyl)phenyl]-2-[(4-nitrobenzoyl)amino]-benzamide;KS176
SMILES:	O=C(C1=C(NC(C2=CC=C([N+]([O-])=O)C=C2)=O)C=CC=C1)NC3=CC=C(CCO)C=C3
Formula:	C₂₂H₁₉N₃O₅
M.Wt:	405.403365373611
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

KS176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter (IC50 values are 0.59 and 1.39 μM in Pheo A and Hoechst 33342 assays respectively). Displays no inhibitory activity against P-gp or MRP1.IC50 value: 0.59( in Pheo A assay), 1.39 μM (in Hoechst 33342 assay).Target: BCRPThe more detailed information please refer to Compound 9 in the reference.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101
2018-0101

Cat. No.	Product name	Field of application
DC71359	UR-MB108	UR-MB108 (Compound 57) is a potent, selective ABCG2 (BCRP) inhibitor with an IC50 of 79 nM. UR-MB108 is stable in blood plasma.
DC9369	YHO-13177	YHO-13177 is a potent and specific inhibitor of BCRP; potentiated the cytotoxicity of SN-38 in cancer cells and no effect on P-glycoprotein–mediated paclitaxel resistance in MDR1-transduced human leukemia K562 cells.
DC9256	KS176	KS176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter (IC50 values are 0.59 and 1.39 μM in Pheo A and Hoechst 33342 assays respectively). Displays no inhibitory activity against P-gp or MRP1.
DC10605	Brevianamide F	Brevianamide F , also known as cyclo-(L-Trp-L-Pro), belongs to a class of naturally occurring 2,5-diketopiperazines.