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NF-κΒ activator 1

  Cat. No.:  DC42357   Featured
Chemical Structure
2387524-59-4
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Field of application
NF-κΒ activator 1 is a potent NF-κΒ activator with an EC50 of 0.9 μM. NF-κΒ activator 1 induces superoxide dismutase (SOD) 2 mRNA expression.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2387524-59-4
Chemical Name: NF-kappaBeta activator 1
Synonyms: NF-κΒ activator 1;NF-kappaBeta activator 1;3-[2-(2-Fluoroanilino)-1,3-thiazol-4-yl]benzoic acid
SMILES: S1C([H])=C(C2C([H])=C([H])C([H])=C(C(=O)O[H])C=2[H])N=C1N([H])C1=C([H])C([H])=C([H])C([H])=C1F
Formula: C16H11FN2O2S
M.Wt: 314.3341
Purity: 98%
Sotrage: Please store the product under the recommended conditions in the Certificate of Analysis.
MSDS
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MSDS_25964_DC42357_2387524-59-4
COA
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Cat. No. Product name Field of application
DC42357 NF-κΒ activator 1 NF-κΒ activator 1 is a potent NF-κΒ activator with an EC50 of 0.9 μM. NF-κΒ activator 1 induces superoxide dismutase (SOD) 2 mRNA expression.
DC10636 SC75741 SC75741 is a potent NF-κB inhibitor with EC50 of 200 nM.
DC7741 JSH-23 JSH-23 is an inhibitor of NF-κB transcriptional activity with IC50 of 7.1 μM.
DC10768 IT 901 IT 901 is a c-Rel inhibitor (IC50 = 3 μM). Inhibits IL-2 expression in activated T-cells in vitro.
DC8827 Didox Didox is a simple, synthetic antioxidant that has been found to reduce the levels of oxidative injury markers.
DC8038 Bay 11-7085 BAY 11-7085 is an irreversible inhibitor of TNFα-induced IκBα phosphorylation with an IC50 value of 10 μM.
DC7869 BAY11-7082 BAY 11-7082 is a NF-κB inhibitor, inhibits TNFα-induced IκBα phosphorylation with IC50 of 10 μM. Also inhibiting components of the ubiquitin system.
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