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Emapunil(AC-5216)

  Cat. No.:  DC7731   Featured
Chemical Structure
226954-04-7
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Field of application
Emapunil(AC-5216;XBD-173) is a translocator protein
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 226954-04-7
Chemical Name: Emapunil
Synonyms: 9H-Purine-9-acetamide,N-ethyl-7,8-dihydro-7-methyl-8-oxo-2-phenyl-N-(phenylmethyl)-;AC 5216;AC-5216;Emapunil;N-BENZYL-N-ETHYL-2-(7-METHYL-8-OXO-2-PHENYL-7H-PURIN-9(8H)-YL)ETHANAMIDE;N-benzyl-N-ethyl-2-(7-methyl-8-oxo-2-phenylpurin-9-yl)acetamide;AC1O5FL9;CHEBI:597751;CHEMBL513922;CTK4E9959;SureCN4757030;UNII-OG837L732J;XBD-173;N-Ethyl-7,8-dihydro-7-methyl-8-oxo-2-phenyl-N-(phenylmethyl)-9H-purine-9-acetamide;NVP-XBD173;9H-Purine-9-acetamide, N-ethyl-7,8-dihydro-7-methyl-8-oxo-2-phenyl-N-(phenylmethyl)-;émapunil;emapunilo;emapunilum;N-Benzyl-N-ethyl-2-(7-methyl-8-oxo-2-phenyl-7,8-dihydro-9H-purin-9-yl)acetamid;N-Benzyl-N-ethyl-2-(7-methyl-8-oxo-2-phenyl-7,8-dihydro-9H-purin-9-yl)acetamide;N-Benzyl-N-éthyl-2-(7-méthyl-8-oxo-2-phényl-7,8-dihydro-9H-purin-9-yl)acétamide;XBD173;ac5216;AC-5216;XBD-173;emapunil(ac-5216);N-(benzyl)-N-ethyl-2-(8-keto-7-methyl-2-phenyl-purin-9-yl)acetamide;n-benzyl-n-ethyl-2-(7-methyl-8-oxo-2-phenyl-7h-purin-9(8h)-yl)acetamide;N-ethyl-2-(7-methyl-8-oxo-2-phenyl-9-purinyl)-N-(phenylmethyl)acetamide;N-ethyl-2-(7-methyl-8-oxo-2-phenylpurin-9-yl)-N-(phenylmethyl)acetamide;N-ethyl-2-(7-methyl-8-oxo-2-phenyl-purin-9-yl)-N-(phenylmethyl)acetamide;N-ethyl-2-(7-methyl-8-oxo-2-phenyl-purin-9-yl)-N-(phenylmethyl)ethanamide;SX-5216;UO7100000;XBD173 |
SMILES: O=C(CN1C2N=C(N=CC=2N(C)C1=O)C1C=CC=CC=1)N(CC)CC1C=CC=CC=1
Formula: C23H23N5O2
M.Wt: 401.461024522781
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Emapunil(AC-5216;XBD-173) is a translocator protein[TSPO (18 kDa)] ligand.IC50 value:Target: TSPO ligandXBD173 enhanced gamma-aminobutyric acid-mediated neurotransmission and counteracted induced panic attacks in rodents in the absence of sedation and tolerance development. XBD173 also exerted antipanic activity in humans and, in contrast to benzodiazepines, did not cause sedation or withdrawal symptoms [1]. The selective TSPO ligand, XBD173 (AC-5216, Emapunil), exerts anxiolytic effects not only in animal models, but also in human volunteers [2].
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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