FIN56

  Cat. No.:  DC10522   Featured
Chemical Structure
1083162-61-1
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More than 5000 active chemicals with high quality for research!
Field of application
FIN56 is a specific inducer of ferroptosis.
Cas No.: 1083162-61-1
Chemical Name: FIN56,FIN-56 ,FIN 56
Synonyms: FIN56,FIN-56 ,FIN 56
SMILES: O=S(C1=CC(/C2=N\O)=C(C3=C2C=C(S(=O)(NC4CCCCC4)=O)C=C3)C=C1)(NC5CCCCC5)=O
Formula: C25H31N3O6S2
M.Wt: 517.66
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: FIN56 is a specific inducer of ferroptosis.
In Vitro: FIN56 causes the loss of GPX4 activity in cell lysates. FIN56-induced cell death is suppressed by GFP-GPX4 fusion protein overexpression. FIN56 triggers ferroptosis through a mechanism involving the regulation of GPX4 protein abundance[1].
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
Cat. No. Product name Field of application
DC9746 RSL3 RSL3 is a ferroptosis activator in a VDAC-independent manner,exhibiting selectivity for tumor cells bearing oncogenic RAS.
DC7920 Liproxstatin-1 Liproxstatin-1 is able to suppress ferroptosis in cells, in Gpx4(-/-) mice, and in a pre-clinical model of ischaemia/reperfusion-induced hepatic damage.
DC10522 FIN56 FIN56 is a specific inducer of ferroptosis.
DC10742 Ferrostatin-1 (Fer-1) Ferrostatin-1 is a selective inhibitor of erastin induced ferroptosis with EC50 value of 60 nM.
DC10839 CIL56(CA3) CIL56 is a small molecule that induces cellular ferroptosis through production of iron-dependent reactive oxygen species (ROS).
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