RSL3

  Cat. No.:  DC9746   Featured
Chemical Structure
1219810-16-8
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Field of application
RSL3 is a ferroptosis activator in a VDAC-independent manner,exhibiting selectivity for tumor cells bearing oncogenic RAS.
Cas No.: 1219810-16-8
Chemical Name: 1H-​Pyrido[3,​4-​b]​indole-​3-​carboxylic acid, 2-​(2-​chloroacetyl)​-​2,​3,​4,​9-​tetrahydro-​1-​[4-​(methoxycarbonyl)​phenyl]​-​, methyl ester, (1S,​3R)​-
Synonyms: RSL 3,RSL-3
SMILES: O=C([C@H]1CC2=C([C@H](C3=CC=C(C(OC)=O)C=C3)N1C(CCl)=O)NC4=C2C=CC=C4)OC
Formula: C23H21ClN2O5
M.Wt: 440.88
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: RSL3 (1S,3R-) is a glutathione peroxidase 4 (GPX4) inhibitor with an EC50 of 10 μM in cellular assay.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
Cat. No. Product name Field of application
DC9746 RSL3 RSL3 is a ferroptosis activator in a VDAC-independent manner,exhibiting selectivity for tumor cells bearing oncogenic RAS.
DC7920 Liproxstatin-1 Liproxstatin-1 is able to suppress ferroptosis in cells, in Gpx4(-/-) mice, and in a pre-clinical model of ischaemia/reperfusion-induced hepatic damage.
DC10522 FIN56 FIN56 is a specific inducer of ferroptosis.
DC10742 Ferrostatin-1 (Fer-1) Ferrostatin-1 is a selective inhibitor of erastin induced ferroptosis with EC50 value of 60 nM.
DC10839 CIL56(CA3) CIL56 is a small molecule that induces cellular ferroptosis through production of iron-dependent reactive oxygen species (ROS).
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