Fexarene

  Cat. No.:  DC8070   Featured
Chemical Structure
574013-68-6
For research use only. We do not sell to patients.
We match the best price and quality on market.
Email:order@dcchemicals.com  sales@dcchemicals.com
Tel:+86-021-58447131
We are official vendor of:
  • 20
  • 19
  • 18
  • 17
  • 16
  • 15
  • 14
  • 12
  • 11
  • 10
  • 9
  • 8
  • 13
  • 6
  • 5
  • 4
  • 3
  • 2
  • 1
More than 5000 active chemicals with high quality for research!
Field of application
Fexarene is a potent, selective farnesoid X receptor agonist.
Cas No.: 574013-68-6
Chemical Name: Fexarene
Synonyms: (E)-methyl 3-(3-(N-(4-styrylbenzyl)cyclohexanecarboxamido)phenyl)acrylate;2-Propenoic acid,3-[3-[(cyclohexylcarbonyl)[[4-(2-phenylethenyl)phenyl]methyl]amino]phenyl]-, methyl ester;FEXARENE;Methyl 3-(3-(N-(4-(styryl)benzyl)cyclohexanecarboxamido)phenyl)acrylate;3-{3-[Cyclohexanecarbonyl-(4-styryl-benzyl)-amino]-phenyl}-acrylic acid methyl ester;BDBM50394413;3-[[4-[(E)-Styryl]benzyl](cyclohexylcarbonyl)amino]cinnamic acid methyl ester;Methyl (E)-3-[3-[cyclohexanecarbonyl-[[4-[(E)-2-phenylethenyl]phenyl]methyl]amino]phenyl]prop-2-enoate
SMILES: O=C(C1CCCCC1)N(C1C=CC=C(/C=C/C(=O)OC)C=1)CC1C=CC(/C=C/C2C=CC=CC=2)=CC=1
Formula: C32H33NO3
M.Wt: 479.609328985214
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Fexarene is a potent, selective farnesoid X receptor agonist. For the detailed information of Fexarene, the solubility of Fexarene in water, the solubility of Fexarene in DMSO, the solubility of Fexarene in PBS buffer, the animal experiment (test) of Fexarene, the cell expriment (test) of Fexarene, the in vivo, in vitro and clinical trial test of Fexarene, the EC50, IC50,and affinity,of Fexarene, For the detailed information of Fexarene, the solubility of Fexarene in water, the solubility of Fexarene in DMSO, the solubility of Fexarene in PBS buffer, the animal experiment (test) of Fexarene, the cell expriment (test) of Fexarene, the in vivo, in vitro and clinical trial test of Fexarene, the EC50, IC50,and affinity,of Fexarene, Please contact DC Chemicals.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
Cat. No. Product name Field of application
DC71956 BMS-986339 BMS-986339 is an orally active, potent FXR agonist. BMS-986339 forms H-bond with His298 and ASN287 residues.
DC7040 WAY-362450 (XL335; Turofexorate isopropyl) WAY-362450 (XL335; Turofexorate isopropyl) is a highly potent, selective, and orally active farnesoid X receptor (FXR) agonist with an EC50 of 4 nM.WAY-362450 is useful for dyslipidemia.
DC10737 Tropifexor (LJN452) Tropifexor (LJN452) is a highly potent non-bile Acid FXR Agonist for the Treatment of Cholestatic Liver Diseases and Nonalcoholic Steatohepatitis (NASH).
DC10470 SB756050 SB-756050 is a Farnesoid X receptor (FXR) (NR1H4) agonist.
DC7430 Obeticholic acid (INT-747) INT-747(Obeticholic acid; 6-ECDCA) is a potent and selective FXR agonist(EC50=99 nM) endowed with anticholestatic activity.
DC7566 GW-4064 GW 4064 is a selective, non-steroidal farnesoid X receptor (FXR) agonist (EC50 = 15 nM).
DC8071 Fexarine Fexarine is a potent, selective farnesoid X receptor agonist.
DC8070 Fexarene Fexarene is a potent, selective farnesoid X receptor agonist.
DC8085 Fexaramine Fexaramine is a potent, selective FXR activator.
DC10868 Cilofexor Cilofexor (GS-9674, GS9674) is novel specific, non-steroidal farnesoid X receptor (FXR) agonist that reduces liver fibrosis and ameliorates portal hypertension in rat NASH models.
X