Fexarine|cas 574013-67-5|DC Chemicals

Cas No.:	574013-67-5
Chemical Name:	Fexarine
Synonyms:	2-Propenoic acid,3-[3-[[[4-(1,3-benzodioxol-5-yl)phenyl]methyl](cyclohexylcarbonyl)amino]phenyl]-, methyl ester;(E)-methyl 3-(3-(N-(4-(benzo[d][1,3]dioxol-5-yl)benzyl)cyclohexanecarboxamido)phenyl)acrylate;FEXARINE;3-{3-[(4-Benzo[1,3]dioxol-5-yl-benzyl)-cyclohexanecarbonyl-amino]-phenyl}-acrylic acid methyl ester;BDBM50167176;3-[[4-(1,3-Benzodioxole-5-yl)benzyl](cyclohexylcarbonyl)amino]cinnamic acid methyl ester;(E)-3-{3-[(4-Benzo[1,3]dioxol-5-yl-benzyl)-cyclohexanecarbonyl-amino]-phenyl}-acrylic acid methyl ester;methyl (E)-3-[3-[[4-(1,3
SMILES:	O=C(C1CCCCC1)N(C1C=CC=C(/C=C/C(=O)OC)C=1)CC1C=CC(C2=CC=C3C(=C2)OCO3)=CC=1
Formula:	C₃₁H₃₁NO₅
M.Wt:	497.581548929214
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Fexarine is a potent, selective farnesoid X receptor agonist. For the detailed information of Fexarine, the solubility of Fexarine in water, the solubility of Fexarine in DMSO, the solubility of Fexarine in PBS buffer, the animal experiment (test) of Fexarine, the cell expriment (test) of Fexarine, the in vivo, in vitro and clinical trial test of Fexarine, the EC50, IC50,and affinity,of Fexarine, For the detailed information of Fexarine, the solubility of Fexarine in water, the solubility of Fexarine in DMSO, the solubility of Fexarine in PBS buffer, the animal experiment (test) of Fexarine, the cell expriment (test) of Fexarine, the in vivo, in vitro and clinical trial test of Fexarine, the EC50, IC50,and affinity,of Fexarine, Please contact DC Chemicals.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101
2018-0101

Cat. No.	Product name	Field of application
DC71956	BMS-986339	BMS-986339 is an orally active, potent FXR agonist. BMS-986339 forms H-bond with His298 and ASN287 residues.
DC7040	WAY-362450 (XL335; Turofexorate isopropyl)	WAY-362450 (XL335; Turofexorate isopropyl) is a highly potent, selective, and orally active farnesoid X receptor (FXR) agonist with an EC50 of 4 nM.WAY-362450 is useful for dyslipidemia.
DC10737	Tropifexor (LJN452)	Tropifexor (LJN452) is a highly potent non-bile Acid FXR Agonist for the Treatment of Cholestatic Liver Diseases and Nonalcoholic Steatohepatitis (NASH).
DC10470	SB756050	SB-756050 is a Farnesoid X receptor (FXR) (NR1H4) agonist.
DC7430	Obeticholic acid (INT-747)	INT-747(Obeticholic acid; 6-ECDCA) is a potent and selective FXR agonist(EC50=99 nM) endowed with anticholestatic activity.
DC7566	GW-4064	GW 4064 is a selective, non-steroidal farnesoid X receptor (FXR) agonist (EC50 = 15 nM).
DC8071	Fexarine	Fexarine is a potent, selective farnesoid X receptor agonist.
DC8070	Fexarene	Fexarene is a potent, selective farnesoid X receptor agonist.
DC8085	Fexaramine	Fexaramine is a potent, selective FXR activator.
DC10868	Cilofexor	Cilofexor (GS-9674, GS9674) is novel specific, non-steroidal farnesoid X receptor (FXR) agonist that reduces liver fibrosis and ameliorates portal hypertension in rat NASH models.