Fluorobexarotene | RAR/RXR Agonist

Cas No.:	1190848-23-7
Chemical Name:	Fluorobexarotene
Synonyms:	Fluorobexarotene;2-fluoro-4-(1-(1,2,3,4-tetrahydro-1,1,4,4,6-pentamethylnaphthalen-7-yl)vinyl)benzoic acid
SMILES:	OC(C1=CC=C(C(C2C(C)=CC3C(CCC(C)(C)C=3C=2)(C)C)=C)C=C1F)=O
Formula:	C₂₄H₂₇FO₂
M.Wt:	366.468390703201
Purity:	98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

MSDS

COA

Cat. No.	Product name	Field of application
DC28238	Fluorobexarotene	Fluorobexarotene (compound 20) is a potent retinoid-X-receptor (RXR) agonist, with a Ki value of 12 nM and an EC50 value of 43 nM for RXRα receptor. Fluorobexarotene possesses an apparent RXR binding affinity that is 75% greater than Bexarotene.
DC10833	LY2955303	LY2955303 is a potent and selective RAR-gamma antagonist for the treatment of osteoarthritis pain.
DC7714	Fenretinide (4-HPR)	Fenretinide (4-HPR) is a synthetic retinoid deriverative. 4-HBR is shown to exhibit binding to the retinoic acid receptors (RAR) at concentrations necessary to induce cell death.
DC10491	CD437	CD437 is a synthetic retinoid that is an RARγ-selective agonist. It displays RARγ-dependent and -independent effects on differentiation and apoptosis.
DC10135	AR-7	AR7 is a retinoic acid receptor α (RARα) antagonist.
DC7054	AM580	A retinoic acid analog and selective RARα agonist