GLP-26|HBV capsid modulator|DC Chemiclas

Cas No.:	2133017-36-2
Chemical Name:	N-(3,4-difluorophenyl)-1,3,5-trimethyl-4-(2-oxo-2-(prop-2-yn-1-ylamino)acetyl)-1H-pyrrole-2-carboxamide
Synonyms:	GLP-26,GLP 26,GLP26
SMILES:	N(C)1C(C)=C(C(C(=O)NCC#C)=O)C(C)=C1C(NC1=CC=C(F)C(F)=C1)=O
Formula:	C₁₉H₁₇F₂N₃O₃
M.Wt:	373.36
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

GLP-26 is a novel potent HBV capsid modulator that reduces secreted HBeAg in HepNTCPDL cells transfected with HBV wild type with EC50 of 0.7 uM; GLP26 is a potent inhibitor of cccDNA formation and HBeAg production against the mutant core T109I, demonstrates synergistic activity with ETV in the HepAD38 system, reducing HBV DNA replication.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

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DC11296	GLP-26	GLP-26 is a novel potent HBV capsid modulator that reduces secreted HBeAg in HepNTCPDL cells transfected with HBV wild type with EC50 of 0.7 uM.