DVR-01

  Cat. No.:  DC72290   Featured
Chemical Structure
330461-34-2
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Field of application
DVR-01 is a HBV inhibitor with EC50 values of 1.7 and 1.6 μM in AML12HBV10 and HepDES19 cells, respectively. DVR-01 shows antiviral activity against drug-resistant HBV mutants with EC50s of 2.403-3.273 μM. DVR-01 can be used for the research of HBV infection and related diseases.
Cas No.: 330461-34-2
Chemical Name: 3-(azepane-1-sulfonyl)-N-benzyl-4-chlorobenzamide
Synonyms: DVR 01;DVR01;DVR-01;3-(Azepan-1-ylsulfonyl)-N-benzyl-4-chlorobenzamide;3-(azepane-1-sulfonyl)-N-benzyl-4-chlorobenzamide
SMILES: S(N1CCCCCC1)(C1C(=CC=C(C(=O)NCC2C=CC=CC=2)C=1)Cl)(=O)=O
Formula: C20H23ClN2O3S
M.Wt: 406.93
Purity: 98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_36741_DC72290_330461-34-2
COA
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Cat. No. Product name Field of application
DC53050 ATI-2173 ATI-2173 is a novel liver-targeted molecule designed to deliver the 5′-monophosphate of clevudine for the treatment of chronic hepatitis B infection.
DC72290 DVR-01 DVR-01 is a HBV inhibitor with EC50 values of 1.7 and 1.6 μM in AML12HBV10 and HepDES19 cells, respectively. DVR-01 shows antiviral activity against drug-resistant HBV mutants with EC50s of 2.403-3.273 μM. DVR-01 can be used for the research of HBV infection and related diseases.
DC47259 Inarigivir ammonium Inarigivir (ORI-9020) ammonium is a dinucleotide antiviral drug which can significantly reduce liver HBV DNA in transgenic mice expressing hepatitis B virus. Inarigivir (ORI-9020) act as an RIG-I agonist to activate cellular innate immune responses.
DC11296 GLP-26 GLP-26 is a novel potent HBV capsid modulator that reduces secreted HBeAg in HepNTCPDL cells transfected with HBV wild type with EC50 of 0.7 uM.
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