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Inarigivir ammonium

  Cat. No.:  DC47259   Featured
Chemical Structure
2172788-92-8
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More than 5000 active chemicals with high quality for research!
Field of application
Inarigivir (ORI-9020) ammonium is a dinucleotide antiviral drug which can significantly reduce liver HBV DNA in transgenic mice expressing hepatitis B virus. Inarigivir (ORI-9020) act as an RIG-I agonist to activate cellular innate immune responses.
Cas No.: 2172788-92-8
Chemical Name: Inarigivir ammonium
Synonyms: Inarigivir ammonium; ORI-9020; ORI 9020; ORI9020; SB-40; SB-9000; SB9000, SB-9000.
SMILES: O(C)[C@H]1[C@@H](O[C@H](CO)[C@H]1OP(OC[C@H]2O[C@H](C[C@@H]2O)N3C=4C(N=C3)=C(N)N=CN4)(=O)S)N5C(=O)NC(=O)C=C5.N
Formula: C20H29N8O10PS
M.Wt: 604.53
Purity: 98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
Cat. No. Product name Field of application
DC53050 ATI-2173 ATI-2173 is a novel liver-targeted molecule designed to deliver the 5′-monophosphate of clevudine for the treatment of chronic hepatitis B infection.
DC72983 ZINC20451377 ZINC20451377 is a small molecule that binds to hepatitis B surface antigen (HBsAg) with high affinity (Kd=65.3 nM), reduces HBsAg levels and HBV virion secretion in cell culture model for HBV.
DC72290 DVR-01 DVR-01 is a HBV inhibitor with EC50 values of 1.7 and 1.6 μM in AML12HBV10 and HepDES19 cells, respectively. DVR-01 shows antiviral activity against drug-resistant HBV mutants with EC50s of 2.403-3.273 μM. DVR-01 can be used for the research of HBV infection and related diseases.
DC47259 Inarigivir ammonium Inarigivir (ORI-9020) ammonium is a dinucleotide antiviral drug which can significantly reduce liver HBV DNA in transgenic mice expressing hepatitis B virus. Inarigivir (ORI-9020) act as an RIG-I agonist to activate cellular innate immune responses.
DC47062 Bersacapavir Bersacapavir is a novel Hepatitis B Virus capsid assembly modulator.
DC11296 GLP-26 GLP-26 is a novel potent HBV capsid modulator that reduces secreted HBeAg in HepNTCPDL cells transfected with HBV wild type with EC50 of 0.7 uM.
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