NS309|NS 309; NS-309|Provide by DC CHEM

Cas No.:	18711-16-5
Chemical Name:	NS 309; NS-309
Synonyms:	NS 309; NS-309
SMILES:	O=C(NC1=C/2C=CC(Cl)=C1Cl)C2=NO
Formula:	C₈H₄Cl₂N₂O₂
M.Wt:	231.04
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

NS309 is a positive modulator of small- and intermediate- conductance Ca2+-activated K+ channels (KCa2 and KCa3.1 channels); increases Ca2+ sensitivity. Displays no activity at BK channels.IC50 value: Ca2+-activated K+ channelTarget:

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101
2018-0101

Cat. No.	Product name	Field of application
DC9600	Senicapoc	Senicapoc(ICA17043) is a potent and selective Gardos channel blocker; blocked Ca(2+)-induced rubidium flux from human RBCs/ inhibited RBC dehydration with IC50s of 11 nM/30 nM, respectively. IC50 value: 11/30 nM [1] Target: Gardos channel in vitro: I
DC8807	Retigabine dihydrochloride	Retigabine 2Hcl (Ezogabine; D23129) is a Kv7.2-7.5 (KCNQ2-5) neuronal potassium channel opener witrh anticonvulsant activity.
DC8269	NS6180	NS6180 is a novel inhibitor of the intermediate-conductance Ca2+-activated K+ channel (KCa3.1)
DC7833	NS309	NS309 is a positive modulator of small- and intermediate- conductance Ca2+-activated K+ channels (KCa2 and KCa3.1 channels); increases Ca2+ sensitivity. Displays no activity at BK channels.
DC6910	NS-1643	NS1643 is a potent human ether-a-go-go related gene (hERG) KV11.1 channel activator (EC50 = 10.5 μM).
DC9734	NS-1619	NS-1619 is a selective MaxiKα (large conductance calcium activated potassium channel) activator.
DC8789	NS 11021	NS 11021 is an activator of large-conductance Ca2+-activated potassium channels (BKCa, KCa1.1).
DC10557	ML402	ML402 is a selective TREK-1 activator.
DC7797	ML365	ML365 is a novel selective small molecule inhibitor of TASK1(KCNK3) with IC50 of 4 nM(thallium influx fluorescent assay) and 16 nM(automated electrophysiology assay).
DC10743	ml335	ML335 is a selective activator of both TREK-1 and TREK-2.