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Erianin

  Cat. No.:  DC23055   Featured
Chemical Structure
95041-90-0
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Field of application
Erianin, often used as an antipyretic and analgesic agent, could inhibit IDO-induced tumor angiogenesis.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 95041-90-0
SMILES: OC1=CC(CCC2=CC(OC)=C(OC)C(OC)=C2)=CC=C1OC
Formula: C18H22O5
M.Wt: 318.36
Purity: >98%, Standard References Grade
Sotrage: 4°C for 1 year, -20°C for more than 2 years
Description: Erianin, often used as an antipyretic and analgesic agent, could inhibit IDO-induced tumor angiogenesis.
In Vitro: Erianin is often used as antipyretic and analgesic agent. Erianin belongs to bibenzyl derivatives in structure, with the activity of anti-virus, anti-bacterial, as well as anti-benign prostatic hyperplasia. Erianin has obvious damage on 2LL-IDO cells, Erianin basically has no cytotoxicity on human normal liver cell line L02, and cell viability is maintained at around 85%[1]. Erianin inhibits the growth of HeLa cells and induces apoptosis in a dose‑ and time‑dependent manner, inducing cell cycle arrest at the G2/M stage. Erianin treatment also increases the expression of Bax and caspase‑3, but decreases levels of Bcl‑2 and phosphorylated‑ERK1/2[2].
References: [1]. Su C, et al. Erianin inhibits indoleamine 2, 3-dioxygenase -induced tumor angiogenesis. Biomed Pharmacother. 2017 Apr;88:521-528. [2]. Li M, et al. Erianin inhibits human cervical cancer cell through regulation of tumor protein p53 via the extracellular signal-regulated kinase signaling pathway. Oncol Lett. 2018 Oct;16(4):5006-5012.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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