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Senkyunolide I

  Cat. No.:  DC23047   Featured
Chemical Structure
94596-28-8
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More than 5000 active chemicals with high quality for research!
Field of application
Senkyunolide I may be an active component of L. chuanxiong, traditionally used to treat migraine, it can protect rat brain against focal cerebral ischemia-reperfusion injury by up-regulating p-Erk1/2, Nrf2/HO-1 and inhibiting caspase 3, the neuroprotectiv
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 94596-28-8
SMILES: O=C1O/C(C2=C1[C@@H](O)[C@H](O)CC2)=CCCC
Formula: C12H16O4
M.Wt: 224.1
Purity: >98%, Standard References Grade
Sotrage: 4°C for 1 year, -20°C for more than 2 years
Description: Senkyunolide I, isolated from Ligusticum chuanxiong Hort, is an anti-migraine compound. Senkyunolide I protects rat brain against focal cerebral ischemia-reperfusion injury by up-regulating p-Erk1/2, Nrf2/HO-1 and inhibiting caspase 3[1][2].
References: [1]. Wang YH, et al. Effect and mechanism of senkyunolide I as an anti-migraine compound from Ligusticum chuanxiong. J Pharm Pharmacol. 2011 Feb;63(2):261-6. [2]. Hu Y, et al. Senkyunolide I protects rat brain against focal cerebral ischemia-reperfusion injury by up-regulating p-Erk1/2, Nrf2/HO-1 and inhibiting caspase 3. Brain Res. 2015 Apr 24;1605:39-48.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
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