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ADAM17 inhibitor SN-4

  Cat. No.:  DC70174  
Chemical Structure
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More than 5000 active chemicals with high quality for research!
Field of application
ADAM17 inhibitor SN-4 is a novel specific inhibitor of A disintegrin and metalloproteinase 17 (ADAM17), inhibits TNF-α cleavage by SN-4 in cells with IC50 of 3.22 uM.SN-4 showed slightly higher activity than the well-studied ADAM17 inhibitor marimastat.SN-4 inhibited the ability of ADAM17 to cleave tumor necrosis factor α (TNF-α) in vitro, inhibited cleavage of CD44 by ADAM17, but not by ADAM10, and to suppress cell invasion.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.:
Chemical Name: ADAM17 inhibitor SN-4
Formula: C23H32N4O3S3
M.Wt: 508.714
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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