BTO-1

  Cat. No.:  DC45827  
Chemical Structure
40647-02-7
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Field of application
BTO-1 is a Polo-like kinase (Plk) inhibitor. BTO-1 is primarily used for phosphorylation and dephosphorylation applications.
Cas No.: 40647-02-7
Chemical Name: BTO-1
SMILES: O=C(C1=[N+]([O-])C2=CC(C#N)=CC([N+]([O-])=O)=C2S1)N
Formula: C9H4N4O4S
M.Wt: 264.22
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC47377 PLK1-IN-2 PLK1-IN-2 is a PLK1 kinase inhibitor with an IC50 value of 0.384 μM.
DC45897 Volasertib trihydrochloride Volasertib (BI 6727) trihydrochloride is an orally active, highly potent and ATP-competitive Polo-like kinase 1 (PLK1) inhibitor with an IC50 of 0.87 nM. Volasertib trihydrochloride inhibits PLK2 and PLK3 with IC50s of 5 and 56 nM, respectively. Volasertib trihydrochloride induces mitotic arrest and apoptosis. Volasertib trihydrochloride, a dihydropteridinone derivative, shows marked antitumor activity in multiple cancer models.
DC45827 BTO-1 BTO-1 is a Polo-like kinase (Plk) inhibitor. BTO-1 is primarily used for phosphorylation and dephosphorylation applications.
DC11635 Poloxin-2 A potent, selective PLK1 PBD inhibitor with IC50 of 1.36 uM.
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