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BZAD-01

  Cat. No.:  DC71365   Featured
Chemical Structure
305339-41-7
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More than 5000 active chemicals with high quality for research!
Field of application
BZAD-01 is a potent, selective and orally active inhibitor of NMDA NR2B subunit, with a Ki of 72 nM. BZAD-01 can improve postural asymmetry as well as Apomorphine-induced rotation.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 305339-41-7
Chemical Name: 4-(Trifluoromethoxy)-N-[2-(trifluoromethyl)benzyl]benzamidine
Synonyms: 4-(Trifluoromethoxy)-N-[2-(trifluoromethyl)benzyl]benzamidine;BZAD-01;4-(Trifluoromethoxy)-N-[2-(trifluoromethyl)benzyl]benzene-carboximidamide;MS-25745;HY-121100;DA-61964;4-Trifluoromethoxy-N-(2-trifluoromethyl-benzyl)-benzamidine;YGOCAMFQDLFNQK-UHFFFAOYSA-N;EX-A4541;4-(trifluoromethoxy)-N'-[[2-(trifluoromethyl)phenyl]methyl]benzenecarboximidamide;AKOS040746660;4-(trifluoromethoxy)-N-(2-trifluoromethylbenzyl)benzamidine;BZAD01; BZAD-01; BZAD 01;;CHEMBL159279;bzad01;CS-0079453;BDBM50124907;305339-41-7;4-(Trifluoromethoxy)-N-(2-(trifluoromethyl)benzyl)benzimidamide
SMILES: N=C(C1=CC=C(OC(F)(F)F)C=C1)NCC2=CC=CC=C2C(F)(F)F
Formula: C16H12N2OF6
M.Wt: 362.26968
Purity: 98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC71365 BZAD-01 BZAD-01 is a potent, selective and orally active inhibitor of NMDA NR2B subunit, with a Ki of 72 nM. BZAD-01 can improve postural asymmetry as well as Apomorphine-induced rotation.
DC44933 Caroverine hydrochloride Caroverine hydrochloride is a potent, competitive and reversible antagonist of NMDA and AMPA glutamate receptor. Caroverine hydrochloride is also an antioxidant and calcium-blocking agent that exhibits vasorelaxant action. Caroverine hydrochloride can be used for the research of inner ear tinnitus.
DC28976 Dizocilpine free base Dizocilpine, a potent anticonvulsant, is a selective and non-competitive NMDA receptor antagonist, with a Kd of 37.2 nM in rat brain membranes. Dizocilpine acts by binding to a site located within the NMDA associated ion channel and thus prevents Ca2+ flux.
DC28270 Topiramate D12 Topiramate D12 (McN 4853 D12) is a deuterium labeled Topiramate. Topiramate is a broad-spectrum antiepileptic agent. Topiramate is a GluR5 receptor antagonist. Topiramate produces its antiepileptic effects through enhancement of GABAergic activity, inhibition of kainate/AMPA receptors, inhibition of voltage-sensitive sodium and calcium channels, increases in potassium conductance, and inhibition of carbonic anhydrase.
DC11197 UoS12258 UoS12258 (UoS-12258) is a selective, positive allosteric modulator of the AMPA receptor with pEC50 of 5.6.
DC9852 Ro 25-6981 maleate Ro 25-6981 is a potent and selective activity-dependent blocker of NMDA receptors containing the NR2B subunit.
DC10763 Philanthotoxin 74 (hydrochloride) Philanthotoxin 74 dihydrochloride (PhTx 74) is an AMPAR antagonist; inhibits GluR3 and GluR1 with IC50s of 263 and 296 nM, respectively.
DC9341 Naspm Naspm(1-Naphthylacetyl spermine) is a potent and selective Ca2+ permeable AMPA receptor(Ca-perm AMPAR) blocker. IC50 value: Target: CP-AMPAR blocker Naspm is a selective blocker of Ca(2+)-permeable GluA2-lacking AMPA receptors, reduced MNNG-induced CA1
DC10382 Farampator Farampator (CX-691;Org24448) is an AMPA receptor positive modulator.
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