| DC29105 |
Epithalon
|
Epitalon is an anti-aging agent and a telomerase activator. Epitalon has an inhibitory effect of the on the development of spontaneous tumors in mice, has geroprotective actions and intranasal administration increases neuronal activity. Epitalon can be used for cancer, old age and Retinitis Pigmentosa. |
| DC8861 |
2'-Deoxythioguanosine
|
6-thio-dG is a nucleoside analog and telomerase substrate. |
| DC11310 |
MST312
|
MST312 is a telomerase inhibitor (IC50 = 0.67 μM in a TRAP assay). |
| DC7085 |
BIBR-1532
|
BIBR 1532 is a potent, selective, non-competitive telomerase inhibitor with IC50 of 100 nM. |
| DC73228 |
Teloxantron
|
Teloxantron (Telomerase inhibitor TXT4) is a potent small molecule inhibitor of telomerase activity with IC50 of 9.61 uM, 7-fold lower than BIBR1532 (Cat# PC-45170), inhibits the processivity of telomerase with preferential DNA damage on telomeres. |
| DC73227 |
DIZ-3
|
DIZ-3 is a dimeric aryl-substituted imidazole as a selective multimeric G-quadruplex (G4) ligand, intercalates into the G4-G4 interface, induces cell cycle arrest and apoptosis, and inhibits cell proliferation in alternative lengthening of telomere (ALT) |
| DC72320 |
L2H2-6OTD
|
L2H2-6OTD, containing one to four G-quadruplex binding loops, is a telomeric inhibitor analogue. l2H2-6OTD has telomerase inhibitory activity with an IC50 value of 15 nM. |
