MLT-943|CAS 1832576-04-1|DC Chemicals

MSDS

Cat. No.	Product name	Field of application
DC46393	JNJ-67856633	JNJ-67856633 is an orally active, first-in-class, potent, selective and allosteric MALT1 protease inhibitor. JNJ-67856633 in some cases lead to tumor stasis.
DC73799	MLT-943	MLT-943 is a potent and selective MALT1 protease inhibitor with IC50 of 40 nM in IL-2 reporter gene assay (Jurkat T cells), inhibits human PBMC IL-2 release with IC50 of 74 nM.
DC73798	MLT-827	MLT-827 is a potent and selective inhibitor of MALT1 paracaspase activity with IC50 of 5 nM.
DC72804	Z-VRPR-FMK	Z-VRPR-FMK is an irreversible MALT1 protein inhibitor. Z-VRPR-FMK inhibits the growth and invasion of diffuse large B-cell lymphoma by inhibiting MALT1-induced NF-κB activation and MMP expression.
DC72411	RGT-068A	RGT-068A is a potent, selective and oral bioavailable MALT1 inhibitor.
DC72232	NVS-MALT1	NVS-MALT1 is a MALT1 allosteric inhibitor.
DC70983	(R)-MLT-985	(R)-MLT-985 (compound 11) is a potent MALT1 protease inhibitor with an IC50 of 3 nM. (R)-MLT-985 has an IC50 of 20 nM for MALT1-dependent IL-2 production in Jurkat cells. (R)-MLT-985 suppresses growth and aberrant CARD11/BCL10/MALT1 complex signaling in ABC-DLBCL cells.