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| Cas No.: | |
| Chemical Name: | WCDD301 |
| Cat. No. | Product name | Field of application |
| DC80040 | 2-Hydroxyterephthalic acid | 2-Hydroxyterephthalic acid is a metal-organic framework (MOF). |
| DC7473 | NVP-BHG712 | NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src and c-Abl with IC50 of 0.395 μM, 1.266 μM and 1.667 μM, respectively. |
| DC10209 | ALW-II-41-27 | ALW-II-41-27 is a novel Eph receptor tyrosine kinase inhibitor, used for cancer treatment. |
| DC81383 | PROTAC KAT2A/B degrader-1 | PROTAC KAT2A/B degrader-1 is an orally active CRBN-baed histone acetyltransferase KAT2A/KAT2B PROTAC degrader. PROTAC KAT2A/B degrader-1 induces degradation of KAT2A and KAT2B proteins. PROTAC KAT2A/B degrader-1 inhibits proliferation of acute myeloid leukemia and small cell lung cancer cells. PROTAC KAT2A/B degrader-1 can be used for the research of acute myeloid leukemia, small cell lung cance. |
| DC80398 | CDK2-IN-51 | CDK2-IN-51 is a pyrazolopyridine derivative, a CDK2 inhibitor with an IC50 of 23.47 nM. CDK2-IN-51 does not have a pro-apoptotic effect and had no significant effect on CDK2 protein expression. CDK2-IN-51 reduces expression of DNA replication factors (Polα, MCM7, ORC2, and ORC4) and pre-G1 cell cycle arrest. CDK2-IN-51 can be used for the research of colorectal cancer. |
| DC80044 | 2-MSP-5-HA-VC-PAB-MMAE | 2-MSP-5-HA-VC-PAB-MMAE (Compound B-1) is a Drug-Linker Conjugates for ADC. 2-MSP-5-HA-VC-PAB-MMAE consists of the ADC Cytotoxin Monomethyl auristatin E and a linker 2-MSP-5-HA-VC-PAB-OH. 2-MSP-5-HA-VC-PAB-MMAE can be used for synthesis of ADCs. |
| DC74406 | WCDD301 | WCDD301 is a high-affinity, orally available agonist of EphA4 receptor. |
| DC74405 | Targefrin | Targefrin is a potent, selective antagonist targeting ligand binding domain of receptor tyrosine kinase EphA2 (EphA2-LBD), binds to EphA2-LBD with Kd of 21 nM (ITC) and shows IC50 value of 10.8 nM in biochemical assays. |
| DC50113 | UniPR129 | UniPR129 is a potent but problematic Eph/ephrin antagonist. UniPR129 has the potential for the research of cancer disease. |