| DCAPI1550 |
Naftopidil |
Naftopidil is an α-1-Adrenergic receptor antagonist and an antihypertensive. |
|
| DCAPI1592 |
Nebivolol hydrochloride |
Nebivolol hydrochloride is a highly selective β1-adrenoceptor antagonist |
|
| DC10114 |
Nifenalol
Featured
|
Nifenalol is a beta-adrenoceptor antagonist. |
|
| DC8583 |
Asenapine Maleate
Featured
|
Novel psychopharmacologic agent. Displays antagonist activity at 5-HT, dopamine, noradrenalin and histamine receptor subtypes (pKi values are 8.60, 8.40, 10.15, 9.75, 10.46, 8.84, 9.60, 9.94, 8.85, 8.90, 8.84, 9.38, 8.95, 8.93, 8.9, 9.49, 8.91, 9.00 and 8 |
|
| DC10384 |
Olodaterol
Featured
|
Olodaterol (BI1744) is a long acting β2-adrenoceptor agonist with an EC50 of 1.4±0.08 nM. |
|
| DC9248 |
Olodaterol(BI-1744) hydrochloride
Featured
|
Olodaterol is a novel, long-acting beta2-adrenergic agonist (LABA) that exerts its pharmacological effect by binding and activating beta2-adrenergic receptors located primarily in the lungs. |
|
| DC9101 |
Phentolamine mesilate |
Phentolamine Mesylate is a nonselective alpha-adrenergic antagonist. |
|
| DC10115 |
Piperoxan hydrochloride
Featured
|
Piperoxan hydrochloride is an α2 adrenoceptor antagonist. |
|
| DC11138 |
Guanabenz acetate |
R15A inhibitor. |
|
| DC12250 |
RS 17053 hydrochloride (RS-17053) |
RS 17053 hydrochloride is a potent and selective α1A adrenoceptor antagonist, with a pKi value of 9.1 in native cell membrane and a pA2 value of 9.8 in functional assays. |
|
| DC11346 |
Salbutamol (hydrochloride)
Featured
|
Salbutamol is an agonist of the β2-adrenergic receptor (β2-AR; Kd = 759 nM in a radioligand binding assay using CHO cells expressing the human receptor). |
|
| DC8436 |
Salmeterol Xinafoate
Featured
|
Salmeterol Xinafoate is a long-acting β2-adrenergic receptor agonist with anti-inflammatory effects, used in the treatment of asthma symptoms and chronic obstructive pulmonary disease (COPD) symptoms. |
|
| DC8610 |
Salmeterol
Featured
|
Salmeterol Xinafoate is a long-acting β2-adrenergic receptor agonist with anti-inflammatory effects, used in the treatment of asthma symptoms and chronic obstructive pulmonary disease (COPD) symptoms. |
|
| DCAPI1485 |
Silodosin
Featured
|
Silodosin(Rapaflo) is an α1-adrenoceptor antagonist with high uroselectivity. Silodosin causes practically no orthostatic hypotension (in contrast to other α1 blockers). Since Silodosin is a highly selective inhibitor of the α1A adrenergic receptor, it ca |
|
| DC9055 |
Sotalol HCl |
Sotalol Hydrochloride is an adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias. |
|
| DC9144 |
Brimonidine tartrate（UK 14,304 tartrate） |
UK 14,304 is a full α2-adrenergic receptor (α2-AR) agonist. |
|
| DC9007 |
Xylazine hydrochloride |
Xylazine Hydrochloride is α2 class of adrenergic receptor agonist. |
|
| DC28082 |
4-Hydroxypropranolol hydrochloride |
4-Hydroxypropranolol hydrochlorid is an active metabolite of Propranolol. 4-Hydroxypropranolol hydrochlorid is of comparable potency to Propranolol. 4-Hydroxypropranolol hydrochlorid inhibits β1- and β2-adrenergic receptors with pA2 values of 8.24 and 8.26, respectively. 4-Hydroxypropranolol hydrochlorid has intrinsic sympathomimetic activity, membrane stabilizing activity and potent antioxidant properties. |
|
| DC28084 |
Hydroxybupropion
Featured
|
Hydroxybupropion is the major active metabolite of Bupropion. Hydroxybupropion is metabolized by CYP2B6.Bupropion is an atypical antidepressant and smoking-cessation agent. Hydroxybupropion inhibits norepinephrine uptake with an IC50 value of 1.7 μM. Hydroxybupropion is also a nACh receptor antagonis tis more potent than Bupropion . |
|
| DC28102 |
SR59230A
Featured
|
SR59230A is a potent, selective, and blood-brain barrier penetrating β3-adrenergic receptor antagonist with IC50s of 40, 408, and 648 nM for β3, β1, and β2 receptors, respectively. |
|
| DC28121 |
CGP 20712 A
Featured
|
CGP 20712 A (CGP 20712 mesylate) is a highly selective β1-adrenoceptor antagonist with an IC50 of 0.7 nM. CGP 20712 A exhibits ~10,000-fold selectivity over β2-adrenoceptors. |
|
| DC28149 |
SR59230A hydrochloride
Featured
|
SR59230A hydrochloride is a potent, selective, and blood-brain barrier penetrating β3-adrenergic receptor antagonist with IC50s of 40, 408, and 648 nM for β3, β1, and β2 receptors, respectively. |
|
| DC28370 |
Dabuzalgron
Featured
|
Dabuzalgron (Ro 115-1240) is an orally active and selective α-1A adrenergic receptor agonist for the treatment of urinary incontinence. Dabuzalgron protects against Doxorubicin-induced cardiotoxicity by preserving mitochondrial function. |
|
| DC28437 |
Arotinolol |
Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker. Arotinolol also shows potency for inhibiting the binding of the radioligand 125I-ICYP to 5HT1B-serotonergic receptor sites. Arotinolol is an antihypertensive agent for the treatment of a variety of cardiovascular pathologies as well as non-cardiovascular diseases. |
|
| DC28528 |
Clonidine |
Clonidine is an alpha 2-adrenergic agonist which is used extensively in anesthesia research. |
|
| DC28787 |
ADRA1D receptor agonist 1 |
ADRA1D receptor agonist 1 (compound (R)-9S) is a potent, selective and orally active α1D adrenoceptor antagonist, with a Ki of 1.6 nM. |
|
| DC28988 |
Arbutamine |
Arbutamine is a short-acting synthetic potent nonselective β-adrenoceptor agonist that increases heart rate, cardiac contractility, and systolic blood pressure. Arbutamine is a catecholamine for a pharmacological cardiac stress agen. |
|
| DC29040 |
(S)-Carvedilol |
(S)-Carvedilol, the S-enantiomer of Carvedilol, is a non-selective β/α-1 blocker. (S)-Carvedilol exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX). |
|
| DC29041 |
(R)-Carvedilol |
(R)-Carvedilol ((R)-BM 14190), the R-enantiomer of Carvedilol, is a non-selective β/α-1 blocker. (R)-Carvedilol exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX). |
|
| DC29044 |
(R)-Terazosin |
(R)-Terazosin is the R-enantiomer of Terazosin. (R)-Terazosin is a potent α-adrenoceptor antagonist with Ki values of 6.51 nM, 1.01 nM and 1.97 nM for α1a, α1b and α1d-adrenoceptor, respectively. |
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