| DC44817 |
3,4,5-Trimethoxybenzaldehyde |
3,4,5-Trimethoxybenzaldehyde is an intermediate for the synthesis of various pharmaceuticals, especially for trimethoprim used to treat bacterial infections, including urinary tract pathogens infection. |
|
| DC44818 |
3-Pentanol |
3-Pentanol is an active organic compound produced by plants and is a component of emitted insect sex pheromones. 3-pentanol elicits plant immunity against microbial pathogens and an insect pest in crop plants. |
|
| DC44819 |
4'-Hydroxy-3'-methylacetophenone |
4'-Hydroxy-3'-methylacetophenone, a phenolic volatile compound, is isolated from Hawaiian green coffee beans (Coffea Arabica L.). 4'-Hydroxy-3'-methylacetophenone has potent antioxidant activities. 4'-Hydroxy-3'-methylacetophenone also can be used to synthesize heterocyclic compounds which have antimycobacterial activity. |
|
| DC44820 |
Carvacrol methyl ether |
Carvacrol methyl ether, a Carvacrol analog, can be isolated from plant volatile oil. Carvacrol methyl ether exhibits antibacterial activity. |
|
| DC44821 |
BPH-1358 free base |
BPH-1358 free base (NSC50460 free base) is a potent human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor with IC50s of 1.8 μM and 110 nM, respectively, and is active against S. aureus in vitro (MIC ~250 ng/mL). |
|
| DC44822 |
Monocaprylin |
Monocaprylin (Glyceryl monocaprylate), a monoglyceride of caprylic acid, exhibits an excellent antibacterial activity. Monocaprylin inhibits a variety of foodborne pathogenic and spoilage microorganisms and has the potential for an alternative food preservative research. |
|
| DC44823 |
Thiomandelic acid |
Thiomandelic acid is a broad spectrum inhibitor of Zinc -lactamases. |
|
| DC44824 |
LpxH-IN-AZ1 |
LpxH-IN-AZ1, a sulfonyl piperazine compound, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor. LpxH-IN-AZ1 is a potent inhibitor of Klebsiella pneumoniae LpxH with IC50 of 0.36 μM . |
|
| DC44903 |
cis-Resveratrol
Featured
|
cis-Resveratrol exhibits signifcant antiviral activity. cis-Resveratrol inhibits enteroviruses with IC50s of 12.2 µM and 37.6 µM for coxsackievirus B3 (CVB3) and enterovirus 71 (EV71), respectively. |
|
| DC44904 |
Golgicide A-2 |
Golgicide A-2 (GCA-2), a Golgicide A (GCA) derivative, is the most active enantiomer of GCA. Golgicide A-2 displays high selectivity and efficiency in killing An. stephensi larvae and can be used for the research of dengue virus spread. |
|
| DC44908 |
2'-Deoxy-5'-O-DMT-2'-fluorouridine |
2'-Deoxy-5'-O-DMT-2'-fluorouridine, a nucleoside analogue, is a 5’-O-DMTr-5-FUDR derivative with potent anti-yellow fever (YFV) activity. |
|
| DC44909 |
6-Chloro-7-deazapurine-β-D-riboside |
Chloro-7-deazapurine-β-D-riboside is a nucleoside derivative and has antifungal activity. |
|
| DC44917 |
2'-O-Methylcytidine |
2'-O-Methylcytidine is a 2'-substituted nucleoside as a inhibitor of HCV replication. 2'-O-Methylcytidine inhibits RNA-dependent RNA polymerase (NS5B)-catalyzed RNA synthesis in vitro, in a manner that is competitive with substrate nucleoside triphosphate. |
|
| DC44923 |
Cys-TAT(47-57) |
Cys-TAT(47-57) (Cys-[HIV-Tat (47-57)]) is an arginine rich cell penetrating peptide derived from the HIV-1 transactivating protein. |
|
| DC44924 |
PKF050-638 |
PKF050-638 is a potent and selective inhibitor of HIV-1 Rev (IC50=0.04 μM). PKF050-638 inhibits the CRM1-mediated Rev nuclear export by disrupting CRM1-NES interaction. |
|
| DC44925 |
Peritassine A |
Peritassine A, an alkaloid that could be isolated from Tripterygium wilfordii Hook. f., possesses anti-HIV activity. |
|
| DC44926 |
2-Hydroxycinnamic acid |
2-Hydroxycinnamic acid is isolated from the methanol extract of Cinnamomum cassia. 2-Hydroxycinnamic acid shows inhibitory effects on infection of HIV/SARS-CoV S pseudovirus with an IC50 of 1.8 mM |
|
| DC44927 |
Schisantherin D |
Schisantherin D is a dibenzocyclooctadiene lignan isolated from the fruit of Schisandra sphenanthera. Schisantherin D shows anti-HIV replication activities with an EC50 of 0.5 μg/mL. Schisantherin D inhibits endothelin receptor B (ETBR) and has hepatoprotective effects. |
|
| DC44928 |
2-Hydroxyacetophenone |
2-Hydroxyacetophenone is a principal root volatile of the Carissa edulis. 2-Hydroxyacetophenone shows inhibitory effects on infection of HIV/SARS-CoV S pseudovirus with an IC50 of 1.8 mM. |
|
| DC44929 |
Cyclotriazadisulfonamide
Featured
|
Cyclotriazadisulfonamide (CADA) is a specific CD4-targeted HIV entry inhibitors. Cyclotriazadisulfonamide (CADA) inhibits the co-translational translocation of human CD4 (huCD4) into the ER lumen in a signal peptide (SP)-dependent way. |
|
| DC44934 |
M2e, human |
M2e, human, consisting of the 23 extracellular residues of M2 (the third integral membrane protein of influenza A), has been remarkably conserved in all human influenza A, which is a valid and versatile vaccine candidate to protect against any strain of human influenza A. |
|
| DC44935 |
2'-Deoxy-2'-fluorouridine |
2'-Deoxy-2'-fluorouridine can be used as an intermediate for antiinfluenza virus agents synthesis. |
|
| DC44936 |
Oseltamivir-acetate |
Oseltamivir-acetate is an impurity of Oseltamivir. Oseltamivir is a neuraminidase inhibitor recommended for the treatment and prophylaxis of influenza A and B. |
|
| DC44937 |
2′-Deoxy-2′-fluoroguanosine |
2′-Deoxy-2′-fluoroguanosine, a nucleoside analog, is a potent inhibitor of influenza virus strains, with an EC90 of <0.35 μM for influenza virus A and B strains. 2′-Deoxy-2′-fluoroguanosine significantly inhibits replication of influenza virus in the upper respiratory tract, resulting in amelioration of fever and nasal inflammation. |
|
| DC45188 |
trans-4-Methylcyclohexanamine |
trans-4-Methylcyclohexanamine is an intermediate and can be used for the development of T. cruzi enzyme inhibitor. |
|
| DC45189 |
2,3-Dehydro-3,4-dihydro ivermectin |
2,3-Dehydro-3,4-dihydro ivermectin is an analog of ivermectin and an anthelmintic. 2,3-Dehydro-3,4-dihydro ivermectin has activity against L. amazonensis promastigotes and amastigotes (IC50s=13.8 and 3.6 µM, respectively) without inducing cytotoxicity to macrophages (IC50= 65.5 µM).
|
|
| DC45190 |
Antitrypanosomal agent 2 |
Antitrypanosomal agent 2 is a potent and selective trypanosoma brucei inhibitor. |
|
| DC45191 |
6-O-Methacrylate |
6-O-Methacrylate, a trilobolide, is isolated from the leaves of Wedelia trilobata. 6-O-Methacrylate displays marked antimalarial activity, with IC50 of 8.9 μg/mL against P. falciparum parasite. 6-O-Methacrylate also has anti-tobacco mosaic virus (TMV) activity. |
|
| DC45344 |
Multicaulisin |
Multicaulisin, a new Diels-Alder type adduct from Morus multicaulis roots, potently effects against Staphylococcus aureus (MRSA) isolates. Multicaulisin is an antibacterial drug and has the potential for MRSA infections research. |
|
| DC45366 |
Bruceine B |
Bruceine B inhibits protein synthesis and nucleic acid synthesis. |
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