| DC72823 |
SU056
Featured
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SU056 is an inhibitor of Y box binding protein 1 (YB-1) with IC50 of 1.73 μM in Sk0V3 cells. |
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| DC72826 |
Usp22i-S02
Featured
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Usp22i-S02(USP22-IN-1, compound S02) is a potent inhibitor of ubiquitin specific peptidase 22 (USP22). It showed anticancer activity by suppressing Foxp3 expression in T-regulatory cells. |
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| DC72829 |
Zuranolone
Featured
|
Zuranolone(SAGE-217, CS-2797) is an orally active and potent neuroactive steroid and positive allosteric modulator of the GABAA receptor, with EC50s of 296 nM for α1β2γ2 receptor. |
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| DC65176 |
LNP023
Featured
|
LNP023 is a highly potent factor B (FB) inhibitor with an IC50 value of 10 nM. LNP023 shows direct, reversible, and high-affinity binding to human FB (KD=7.9 nM). |
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| DC65177 |
8-Azaadenosine
Featured
|
8-Azaadenosine is a potent ADAR1 inhibitor and an A-to-I editing inhibitor. 8-Azaadenosine blocks RNA editing and inhibits proliferation, 3D growth, invasion, and migration in thyroid cancer cells. |
|
| DC65179 |
Dlin-MC4-DMA
Featured
|
D-Lin-MC4-DMA(MC4) is a cationic lipid that has been synthesized for Lipid nanoparticles (LNPs) to deliver the siRNA. |
|
| DC65180 |
DLin-MC2-DMA
Featured
|
D-Lin-MC2-DMA(MC2) is a cationic lipid that has been synthesized for Lipid nanoparticles (LNPs) to deliver the siRNA. |
|
| DC65181 |
WAY-299801
Featured
|
WAY-299801 is an antiacterial agent. WAY-299801 showed interesting in vitro antimycobacterial activity against some strains of Mycobacterium and clin. isolates of M. tuberculosis. |
|
| DC65183 |
WAY-313013
Featured
|
WAY-313013 is a p38a Mitogen-Activated Protein Kinase inhibitor. |
|
| DC65184 |
WAY-640810
Featured
|
WAY-640810 is a chemical agent which may alter the lifespan of a eukaryotic organism. |
|
| DC65185 |
AD-57
Featured
|
AD-57, also known as KIRA 1, is an IRE1 inhibitor for cancer inflammation autoimmune disease therapy. |
|
| DC65186 |
DCFH
Featured
|
DCFH, also known as 2',7'-dichlorodihydrofluorescein, is a fluororescent agent. It is a key chemcial for the dichlorofluorescin (DCFH) oxidation assay. |
|
| DC65187 |
HHS-0701
Featured
|
HHS-0701, a sulfur-triazole exchange (SuTEx) ligand, is a potent tyrosine-reactive prostaglandin reductase 2 (PTGR2) inhibitor. HHS-0701 blocks PTGR2 metabolism of the lipid substrate 15-Keto-PGE2. |
|
| DC65188 |
Moracin C
Featured
|
Moracin C is a phenolic compound isolated from Artocarpus heterophyllus. Moracin C suppresses Lipopolysaccharide-Activated Inflammatory Responses in Murine Raw264.7 Macrophages. |
|
| DC65189 |
BDTX-1535
Featured
|
BDTX-1535 is a potent, selective, brain penetrant and irreversible MasterKey inhibitor of EGFR mutations that expressed in glioblastoma multiforme (GBM) and intrinsic and acquired resistance EGFR mutations in non-small cell lung cancer (NSCLC). |
|
| DC65190 |
NSC321039
Featured
|
NSC321039, also known as hMAO-B-IN-4, is a selective, reversible and blood–brain barrier (BBB) penetrable human monoamine oxidase-B (hMAO-B) inhibitor with an IC50 value of 0.067 μM. |
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| DC65191 |
WAY-658513
Featured
|
WAY-658513 is a multiple kinase inhbitor. WAY658513 was shown to inhibit ROCK I, ERK2, GSK3, and PKA with Ki <1 μM. |
|
| DC65192 |
RXN00442
Featured
|
RXN00442, also known as EGFR-IN-11, is a fourth-generation EGFR-tyrosine kinase inhibitor (EGFR-TKI). This compound was first reported in Eur J Med Chem. |
|
| DC65193 |
WAY-299838
Featured
|
WAY-299838 is a useful chemical agent for chemical synthesis of hypoxia-inducible factor-1 inhibitor. |
|
| DC65194 |
HUN39963
Featured
|
HUN39963, also known as LDH-IN-2 is an inhibitor of glycolate oxidase. This compound was first reported in J Med Chem. |
|
| DC65195 |
ZVN26391
Featured
|
ZVN26391, also known as NLRP3-IN-10, is a IL-1β inhibitor for the treatment of inflammation and inflammation-related disease (neurogenic inflammation, Alzheimer disease, etc.). |
|
| DC65196 |
CUN11141
Featured
|
CUN11141, also known as BRD4 Inhibitor-20, is a potent orally active bromodomain protein 4 (BRD4) inhibitor. It can be used for the research of kinds of cancer, such as colon cancer. |
|
| DC65197 |
GSK-3β Inhibitor II
Featured
|
GSK3β Inhibitor II, also known as KIN 001-042, also known as GSK-3β Inhibitor II, is a GSK-3β inhibitor. |
|
| DC65198 |
VUN28691
Featured
|
VUN28691, also known as p38α inhibitor 3, is a p38α inhibitor for treatment of p38-α kinase-mediated conditions. |
|
| DC65199 |
1-(4-nitrophenyl)-3-(1-(6-(trifluoromethyl)pyridin-2-yl)piperidin-4-yl)thiourea
Featured
|
DUN51106, also known as USP8-IN-3, is a deubiquitinase USP8 inhibitor (IC50 = 4.0 μM) for treatment of malignant tumors. |
|
| DC65200 |
DKI5
Featured
|
DKI5, also known as (E)-N’-benzylidenehydrazinecarbothiohydrazide, is a LOX-1 inhibitor with an IC50 value of 22.5 μM. DKI5 strongly inhibits lipid peroxidation. |
|
| DC65201 |
J-3-54
Featured
|
J 3-54 , also known as LSD1-IN-24, is a selective LSD1 inhibitor with IC50 = 0.247 μM. VUN34592 can mediate the expression of PD-L1, enhance T cell killing response, and can be used in cancer research. |
|
| DC65202 |
CAY10462
Featured
|
CAY10462 is the hydrochloride salt of CAY10434 and selective inhibitor of the 20-HETE synthase CYP4A11 exhibiting an IC50 of 8.8 nM when tested in human renal microsomes.4 CAY10434 is nearly 200 times less potent as an inhibitor of 1A, 1C, and 3A CYP450.
|
|
| DC65203 |
ThioLox
Featured
|
ThioLox is a competitive 15-lipoxygenase-1 (15-LOX-1) inhibitor. ThioLox shows anti-inflammatory and neuroprotective properties. |
|
| DC65204 |
Pomalidomide-piperazine
Featured
|
Pomalidomide-piperazine is an active compound that can be used to synthesis the E3 ligand for PROTAC. |
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