| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC65158 | Methyl 7α-Hydroxy-3-ketocholanoate Featured |
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| DC65159 | CPD101507-B3 Featured |
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| DC65160 | CPD101507-A1 Featured |
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| DC65161 | 3-1-aminoethyl-5-(trifluoromethyl)aniline hydrochloride Featured |
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| DC65162 | CPD3223 Featured |
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| DC65163 | IMidazo[1,2-d][1,4]benzoxazepine,9-broMo-5,6-dihydro-2-iodo-[1,4]oxazepine Featured |
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| DC65164 | 6-(4-chlorobenzoyl)-4-(3-chlorophenyl)-1-methylquinolin-2(1H)-one Featured |
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| DC65165 | Allo-UDCA Featured |
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| DC65166 | 2,6-Difluoro-3,5-dimethoxyaniline Featured |
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| DC65167 | (3beta,7alpha)-3,7-Dihydroxychol-4-3n-24-oic acid Featured |
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| DC65168 | (S)-3-Cyclopropyl-5-isopropylimidazolidine-2,4-dione Featured |
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| DC65169 | CPD2809-SM Featured |
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| DC65170 | CPD2809-A6 Featured |
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| DC65171 | 2-Isopropyl-4-methylpyridin-3-amine Featured |
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| DC65172 | CPD2810-A4 Featured |
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| DC65173 | 1-Boc-3R-fluoro-4S-piperidinol Featured |
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| DC65174 | CPD1584-B3 HCl Featured |
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| DC65175 | CPD10000-A2 Featured |
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| DC60444 | FX-909 Featured | FX-909（FX 909） is a first-in-class inverse agonist of the peroxisome proliferator-activated receptor gamma (PPARG) lineage transcription factor with EC50 of 1 nM and shows >2000-fold selectivity for PPARG over PPARA/PPARD - acting through a mechanism that promotes a repressive conformation of PPARG. |
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| DC60445 | BAY-2965501 Featured | BAY-2965501 is a first-in-class a diacylglycerol kinase zeta (DGKζ, lipid kinase) inhibitor with IC50 of 27 nM/35 nM (human/mouse) and shows >20-fold selectivity for DGKζ over other DGK isotypes. BAY-2965501 blocks DGKζ in T-cells to activate them |
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| DC60447 | ARV-766 Featured | ARV-766 is an orally active and potent proteolysis targeting chimera (PROTAC) protein degrader. ARV-766 degrades wild-type androgen receptor (AR) but also relevant AR LBD mutants, including the most prevalent AR L702H, H875Y, and T878A mutations[1]. |
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| DC65209 | M3913 Featured | M3913 is an antitumor compound. |
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| DC60449 | TNG260 Featured | TNG260 is a CoREST-selective deacetylase inhibitor and shows 500-fold selectivity for the CoREST complex over the other HDAC1-containing complexes, NuRD and Sin3. |
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| DC60450 | ZW251 Featured | ZW251 is an antibody drug conjugate (ADC) consisting of a topoisomerase l inhibitor payload conjugated to an antibody targeting Glypican-3(GPC3). |
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| DC60451 | MRT-2539 Featured | MRT-2359 a potent, selective and orally bioavailable GSPT1-directed molecular glue degrader (MGD). |
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| DC60452 | RMC-6291 Featured | RMC-6291 is a potent covalent inhibitor of KRASG12C(ON) that forms a tri-complex within tumor cells between KRASG12C(ON) and cyclophilin A (CypA). RMC-6291 overcomes limitations of first-generation KRASG12C(OFF) inhibitors in preclinical models by directly targeting the active form of this important oncogenic driver. |
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| DC60453 | DT-109 Featured | DT-109 is a glycine-based tripeptide (Gly-Gly-Leu) that lowers steatohepatitis and hepatic fibrosis via induction of fatty acid (FA) degradation and antioxidant defense through de novo glutathione (GSH) biosynthesis. |
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| DC72806 | Camlipixant Featured | Camlipixant (BLU-5937) a potent, selective, non-competitive and orally active P2X3 homotrimeric receptor antagonist with an IC50 of 25 nM against hP2X3 homotrimeric. Camlipixant shows potent anti-tussive effect and no taste alteration. Camlipixant can be used for the research of unexplained, refractory chronic cough. |
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| DC72808 | UCM-1306 Featured | UCM1306 is a potent and orally active human dopamine D1 receptor allosteric modulator (PAM). UCM-1306 increases the endogenous dopamine (DA) maximal effect both in human and mouse D1 receptors. UCM-1306 is not only for improving motor symptoms but also for addressing the key comorbid cognitive impairment associated with long-term Parkinson’s disease (PD). |
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| DC72822 | MS023 hydrochloride Featured | MS023 hydrochloride is a potent, selective and cell-active inhibitor of human type I protein arginine methyltransferases (PRMT), with IC50 values of 30, 119, 83, 4 and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6, and PRMT8, respectively. |
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