| DC90070 |
(-)-tetrabenazine
Featured
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Inhibitor of VMAT-2, decreasing monamines into synaptic vesicles |
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| DCC0270 |
5-alpha-hydroxy-laxogenin
Featured
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5-alpha-hydroxy-laxogenin is a derivative of the spirostane-type steroid, laxogenin. 5α-Hydroxy-laxogenin can be used as a plant-based anabolic agent as a dietary supplement. |
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| DCC0281 |
5-ht3 Antagonist-4i
Featured
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5-HT3 antagonist 4 is a 5-HT3 receptor (5HT3R) antagonist. 5-HT3 antagonist 4 prevents diabetes-induced depressive phenotypes in mice. |
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| DCC0466 |
Adamts-5 Inhibitor
Featured
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Selective inhibitor of ADAMTS-5 (A disintegrin and metalloproteinase with thrombospondin motifs 5 or aggrecanase-2) |
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| DCC0543 |
Alk-001
Featured
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ALK-001 is a vitamin A analog potentially for the treatment of Stargardt’s disease. |
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| DCC0545 |
Alkyne-a-dsbso
Featured
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Novel Enrichable and MS-Cleavable Cross-linker to Define Protein-Protein Interactions by Mass Spectrometry |
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| DCC0593 |
Sotorasib racemate
Featured
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Sotorasib racemate (Compound A) is an orally active racemate of Sotorasib, a covalent inhibitor of KRAS G12C mutant which induces adaptive feedback activation of MAPK pathway. Sotorasib racemate also exerts inhibitor activity against KRAS G12C induced cancer and can be applied to cancer research. |
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| DCC0661 |
Ap1510
Featured
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AP1510 is a potent cell-permeable ligand for human FKBP12. AP1510 regulates protein-protein interactions through dimerization. |
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| DCC0768 |
aTAG 4531
Featured
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aTAG 4531 (CFT-4531) is a potent, selective, and onmechanism tool degrader of MTH1 with DC50 value of 0.28 nM and Ki value of 1.8 nM. degradation activity is due to the intricate formation of the ternary complex between the MTH1 aTAG, CRBN E3 ligase, and aTAG tool degrader . |
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| DCC0844 |
Azd1897
Featured
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AZD1897 is a PIM1, PIM2, and PIM3 inhibitor with IC50 values of less than 3 nM for these three PIM kinases. AZD1897 exhibits anticancer activity and synergistically inhibits the activity of acute myeloid leukemia (AML) cells in combination with Capivasertib (HY-15431). This synergistic inhibitory effect is achieved through the inhibition of the mTOR and MCL1 pathways. |
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| DCC0857 |
Azide-a-dsbso
Featured
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Azide-A-DSBSO crosslinker is a mass spectrometry (MS)-cleavable, membrane-permeable, homobifunctional, azide-labeled, acid-cleavable cross-linked peptide. Azide-A-DSBSO crosslinker enables the study of protein-protein interactions via cross-linking mass spectrometry (XL-MS). |
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| DCC0907 |
Bb-83698
Featured
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BB-83698 is a peptide deformylase inhibitor and potent antimicrobial with excellent activity against streptococci and Moraxella catarrhalis strains. |
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| DC90961 |
Bff-816
Featured
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Novel, systemically active kynurenine aminotransferase 2 (KAT2) inhibitor, significantly decreased escape latency in the Morris water maze, indicating improved performance in spatial and contextual memorynovel |
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| DCC0970 |
Bi-1750
Featured
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BI-1750 is a highly selective and stable fluorogenic substrate designed for Cathepsin C (CatC), a lysosomal cysteine protease involved in various physiological and pathological processes. Its unique properties make it a powerful tool for studying CatC activity in both research and drug development contexts. |
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| DCC1048 |
Bms184394
Featured
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Novel selective inhibitor of RARγ |
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| DCC1108 |
Bpn-14136
Featured
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Novel RBP4 antagonist with good in vitro potency and selectivity and optimal rodent pharmacokinetic (PK) and pharmacodynamic (PD) characteristics |
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| DCC1166 |
BU99008
Featured
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BU99008 is non-radiolabled compound. 11C-BU99008 is a PET Ligand for the imidazoline2 Binding Sites in Rhesus Brain. |
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| DCC1169 |
Bulgecin A
Featured
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Bulgecin A is an inhibitor of binuclear metallo-beta-lactamases and Lytic transglycosolase. |
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| DCC1203 |
Calcein-am
Featured
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Cell permeable derivative of calcein, becoming fluorescent on hydrolysis |
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| DCC1260 |
CBL0137 hydrochloride
Featured
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CBL0137 (CBL-0137) activates p53 and inhibits NF-kB with EC50s of 0.37 μM and 0.47 μM in the cell-based p53 and NF-kB reporter assays, respectively. It also inhibits histone chaperone FACT (facilitates chromatin transcription complex). |
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| DCC1281 |
(E/Z)-CCR-11
Featured
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(E/Z)-CCR-11 (Comp 12) is a selective CD38 inhibitor, with an IC50 of 20.8 μM against CD38 cyclase. (E/Z)-CCR-11 promotes increases in cellular NAD+ levels and interferon γ. |
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| DCC1351 |
Cga-jk3
Featured
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CGA-JK3 is CGA-JK3 is an ATP-competitive inhibitor of IKKβ-catalyzed kinase activity. CGA-JK3 inhibits IκBα phosphorylation in LPS (HY-D1056) - induced RAW 264.7 cells. |
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| DCC1618 |
Cyanotryptophan
Featured
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Blue fluorescent amino acid, exhibiting blue fluorescence (λ max ~ 405 nm) with a high quantum yield and long lifetime |
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| DCC1706 |
Dd04107
Featured
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Novel inhibitor of α-calcitonin gene-related peptide (α-CGRP) exocytotic release from primary sensory neurons, selectively interacting with Synaptotagmin 1 |
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| DCC1779 |
Did Perchlorate
Featured
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Lipophilic fluorescent reagent, labeling membranes and other hydrophobic structures |
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| DCC1837 |
Dolastatin 10
Featured
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Highly potent cytotoxic microtubule inhibitor |
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| DCC1870 |
Dsm502
Featured
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Novel potent inhibitor of dihydroorotate dehydrogenase (DHODH) |
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| DCC1968 |
Entasobulin
Featured
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Entasobulin is a β-tubulin polymerization inhibitor with potential anticancer activity. |
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| DCC2205 |
Gac0001e5
Featured
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GAC0003A4 is an LXR inverse agonist that inhibits LXR transcriptional activity. GAC0003A4 also efficiently degrades LXRβ protein. GAC0003A4 has the potential to be used in advanced pancreatic cancer and other refractory malignancies. |
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| DCC2206 |
Gac0003a4
Featured
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Novel LXR inverse agonist, functioning as LXR a degrader, significantly reducing LXR protein levels in PDAC cell lines |
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