Cat. No. | Product name | CAS No. |
DC72726 |
HQ005
Featured
HQ005 is a potent CCNK degrader with an DC50 value of 0.041 µM. HQ005 is a molecular-glue degrader that mediates interactions between target proteins and components of the ubiquitin-proteasome system to cause selective protein degradation. |
2750644-31-4 |
DC72738 |
YLF-466D
Featured
YLF-466D is an AMPK activator that inhibits platelet aggregation with IC50 of 84 μM. |
1273323-67-3 |
DC72741 |
BGB 15025
Featured
BGB-15025 is a potent and selective HPK1 inhibitor. It is used in the treatment of various cancers. |
2766481-17-6 |
DC72747 |
Elenestinib
Featured
Elenestinib (BLU-263) is a potent and orally active tyrosine kinase inhibitor. Elenestinib has the potential for the research of systemic mastocytosis (SM). |
2505078-08-8 |
DC72750 |
GNE-9822
Featured
GNE-9822 is a potent, orally active and selective ITK inhibitor with a Ki value of 0.7 nM. GNE-9822 has good ADME properties. GNE-9822 can be used in research of asthma. |
1557232-32-2 |
DC72751 |
CT52923
Featured
CT52923 is a selective, orally active platelet-derived growth factor receptor (PDGFR) antagonist. CT52923 also is an ATP-competitive inhibitor. CT52923 can be used for the research variety of pathological diseases, including atherosclerosis, glomerulonephritis, liver cirrhosis, pulmonary fibrosis, and cancer. |
205256-55-9 |
DC72756 |
JQAD1
Featured
JQAD1 is a CRBN-dependent PROTAC that selectively targets EP300 for degradation. JQAD1 suppresses EP300 expression and the H3K27ac modification. JQAD1 induces apoptosis. JQAD1 can be used in research of cancer. |
2417097-18-6 |
DC72765 |
Evocalcet
Featured
Evocalcet (KHK7580) is an novel oral calcimimetic agent which acts via allosteric activation of the calcium sensing receptor (CaSR). Evocalcet (0, 20 and 60 nM) dose-dependently increases cytoplasmic [Ca2+] concentrations with an EC50 value of 92.7 nM in hCaR-HEK293 cells. |
870964-67-3 |
DC72766 |
PF-07054894
Featured
PF-07054894 is a potent CCR6 antagonist. PF-07054894 targets G protein-coupled receptor (GPCR). PF-07054894 can be used in research of inflammatory bowel disease. |
2413693-96-4 |
DC72770 |
Zongertinib
Featured
Zongertinib is a potent tyrosine kinase inhibitor. Zongertinib can be used as an antineoplastic agent. Zongertinib also has been tested as pHER2 and EGFR inhibitor inhibiting a wide variety of cancers. |
2728667-27-2 |
DC72773 |
Brigimadlin
Featured
Brigimadlin is an E3 ubiquitin-protein ligase MDM-2 inhibitor. Brigimadlin serves as an antineoplastic agent. |
2095116-40-6 |
DC72775 |
iJMJD6
Featured
iJMJD6(WL12) is an inhibitor of arginine demethylase JMJD6 with an IC50 value of 0.22 μM. |
899548-78-8 |
DC72776 |
SD49-7
Featured
SD49-7 is an inhibitor of histone lysine-specific demethylase 4 (KDM4) with an IC50 of 0.19 µM. |
54009-54-0 |
DC72777 |
DS-9300
Featured
DS-9300 is a potent, orally active, selective EP300/CBP HAT inhibitor with an IC50 value of 28 nM. DS-9300 has anticancer activity and can be used in prostate cancer disease research. |
2259641-46-6 |
DC72779 |
RK-701
Featured
RK-701 is an highly selective and non-genotoxic inhibitor of G9a with IC50 value of 23-27 nM. RK-701 selectively up-regulates HbF, γ- Globin, BGLT3 expression, down-regulates H3K9me2 expression. RK-701 also has inhibition for BCL11A and ZBTB7A. |
2648855-18-7 |
DC72785 |
TP0597850
Featured
TP0597850 is a selective inhibitor of MMP2 (IC50=0.22 nM). TP0597850 has a long MMP2 dissociation half-life (t1/2=265 min). |
2642181-22-2 |
DC72788 |
AZD0095
Featured
AZD0095 is a selective and orally active MCT4 inhibitor (IC50: 1.3 nM). AZD0095 effectively inhibits the tumor growth in NCI-H358 xenograft in combination with Cediranib. |
2750001-23-9 |
DC72794 |
Zidesamtinib
Featured
Zidesamtinib (NVL-520) is a potent, selective, orally active and brain-penetrant inhibitor of diverse ROS1 fusions and resistance mutations, with IC50s of 0.7 and 7.9 nM for wild-type ROS1 and ROS1 G2032R, respectively, and spares TRK inhibition. Zidesamtinib can be used for the research of cancer. |
2739829-00-4 |
DC60391 | WEHL-03 Featured | 15827-80-2 |
DC60392 | WEHL-04 Featured | 114744-51-3 |
DC60393 | T3 Featured | 5817-39-0 |
DC60394 |
PU-WS13
Featured
PU-WS13 is a selective Grp94 inhibitor, with an EC50 of 0.22 μM. |
1454619-14-7 |