Cat. No. | Product name | CAS No. |
DC65581 |
AP-C2
Featured
AP-C2 is a potent guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) inhibitor. |
682793-07-3 |
DC65582 |
Cbl-b-IN-5
Featured
Cbl-b-IN-5 (compound 6) is a Cbl-b inhibitor. |
2368835-59-8 |
DC65583 |
Nurr1 agonist 2
Featured
Nurr1 agonist 3 (Compound 7) is a Nurr1 agonist. |
742058-34-0 |
DC65584 |
Antitumor agent-93
Featured
Antitumor agent-93 (compound 7D) is an anticancer agent. |
1681019-44-2 |
DC65585 |
Sotuletinib dihydrochloride
Featured
Sotuletinib, also known as BLZ945, is a potent and selective CSF-1R kinase inhibitor. BLZ945 showed effects of CSF1R inhibition on other tumor-infiltrating immune cells. BLZ945 attenuates the turnover rate of TAMs while increasing the number of CD8+ T cells that infiltrate cervical and breast carcinomas. BLZ945 decreases the growth of malignant cells in the mouse mammary tumor virus-driven polyomavirus middle T antigen (MMTV-PyMT) model of mammary carcinogenesis. BLZ945 prevents tumor progression in the keratin 14-expressing human papillomavirus type 16 (K14-HPV-16) transgenic model of cervical carcinogenesis. |
2222138-40-9 |
DC65586 |
B-Raf IN 15
Featured
B-Raf IN 15 (Compound 7) is a BRAF inhibitor. |
832107-31-0 |
DC65587 |
ARC7
Featured
ARC7 can act as a probe for secondary metabolism in S. coelicolor. |
681212-58-8 |
DC65588 |
5-LOX-IN-2
Featured
5-LOX-IN-2 is an inhibitor of 5-lipoxygenase (5-LOX). |
179691-97-5 |
DC65589 |
AKT-IN-18
Featured
AKT-IN-18, an inhibitor of Akt, inhibits Akt. |
|
DC65590 |
Antitumor agent-113
Featured
Antitumor agent-113 shows cytotoxic effects on A549 cells. |
|
DC65595 |
Ethidium bromide
Featured
Ethidium bromide is an intercalating agent commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis. |
1239-45-8 |
DC65596 |
GDC-0068 (dihydrochloride)
Featured
Ipatasertib dihydrochloride (GDC-0068 dihydrochloride) is a highly selective pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 5/18/8 nM, 620-fold selectivity over PKA. |
1396257-94-5 |
DC65597 |
T807
Featured
T807 a novel tau positron emission tomography (PET) tracer. |
1415379-56-4 |
DC65598 | 2-Chloro-3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol Featured | 1799612-10-4 |
DC65599 |
E3 ligase Ligand-Linker Conjugates 3
Featured
E3 ligase Ligand-Linker Conjugates 3 is a synthesized compound that incorporates an E3 ligase ligand and a linker used in PROTAC technology. |
2101200-09-1 |
DC65600 |
42-(2-Tetrazolyl)rapamycin
Featured
42-(2-Tetrazolyl)rapamycin is a prodrug compound of a rapamycin analog extracted from patent US 20080171763 A1, Example 1. Rapamycin is a specific mTOR inhibitor. |
221877-56-1 |
DC65601 |
Hoechst 33342
Featured
Hoechst 33342 is a DNA minor groove binder used fluorochrome for visualizing cellular DNA. |
23491-52-3 |
DC65602 |
BMS-309403 sodium
Featured
BMS-309403 sodium is a potent, orally active, and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor, with Kis of <2, 250, and 350 nM for FABP4, FABP3, and FABP5, respectively. BMS-309403 sodium interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS-309403 sodium improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells. |
2802523-05-1 |
DC65603 |
Mepazine
Featured
Mepazine (Pecazine) is a potent and selective MALT1 inhibitor. Mepazine inhibits GSTMALT1 full length and GSTMALT1 325-760 with IC50s of 0.83 and 0.42 μM, respectively. Mepazine affects viability of ABC-DLBCL cells by enhancing apoptosis. |
60-89-9 |
DC65604 |
L-Buthionine (S,R)-sulfoximine
Featured
L-Buthionine-(S,R)-sulfoximine is a cell-permeable, potent, fast acting and irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels. The IC50 value of L-Buthionine-(S,R)-sulfoximine on melanoma, breast and ovarian tumor specimens are 1.9 μM, 8.6 μM, and 29 μM, respectively. |
83730-53-4 |
DC60491 |
C11-MRTX
Featured
C11-MRTX is a lipid-conjugated MRTX849 analogue with a 11-carbon tail. C11-MRTX is a nonaggregating potent cellular inhibitor of K-Ras(G12C). |
|
DC65591 |
Pim-1 kinase inhibitor 4
Featured
Pim-1 kinase inhibitor 4 (Compound 10f) is a Pim-1 kinase inhibitor. |