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Cat. No. Product name CAS No.
DC65581 AP-C2 Featured

AP-C2 is a potent guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) inhibitor.

682793-07-3
DC65582 Cbl-b-IN-5 Featured

Cbl-b-IN-5 (compound 6) is a Cbl-b inhibitor.

2368835-59-8
DC65583 Nurr1 agonist 2 Featured

Nurr1 agonist 3 (Compound 7) is a Nurr1 agonist.

742058-34-0
DC65584 Antitumor agent-93 Featured

Antitumor agent-93 (compound 7D) is an anticancer agent.

1681019-44-2
DC65585 Sotuletinib dihydrochloride Featured

Sotuletinib, also known as BLZ945, is a potent and selective CSF-1R kinase inhibitor. BLZ945 showed effects of CSF1R inhibition on other tumor-infiltrating immune cells. BLZ945 attenuates the turnover rate of TAMs while increasing the number of CD8+ T cells that infiltrate cervical and breast carcinomas. BLZ945 decreases the growth of malignant cells in the mouse mammary tumor virus-driven polyomavirus middle T antigen (MMTV-PyMT) model of mammary carcinogenesis. BLZ945 prevents tumor progression in the keratin 14-expressing human papillomavirus type 16 (K14-HPV-16) transgenic model of cervical carcinogenesis.

2222138-40-9
DC65586 B-Raf IN 15 Featured

B-Raf IN 15 (Compound 7) is a BRAF inhibitor.

832107-31-0
DC65587 ARC7 Featured

ARC7 can act as a probe for secondary metabolism in S. coelicolor.

681212-58-8
DC65588 5-LOX-IN-2 Featured

5-LOX-IN-2 is an inhibitor of 5-lipoxygenase (5-LOX).

179691-97-5
DC65589 AKT-IN-18 Featured

AKT-IN-18, an inhibitor of Akt, inhibits Akt.

DC65590 Antitumor agent-113 Featured

Antitumor agent-113 shows cytotoxic effects on A549 cells.

DC65595 Ethidium bromide Featured

Ethidium bromide is an intercalating agent commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis.

1239-45-8
DC65596 GDC-0068 (dihydrochloride) Featured

Ipatasertib dihydrochloride (GDC-0068 dihydrochloride) is a highly selective pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 5/18/8 nM, 620-fold selectivity over PKA.

1396257-94-5
DC65597 T807 Featured

T807 a novel tau positron emission tomography (PET) tracer.

1415379-56-4
DC65598 2-Chloro-3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol Featured

1799612-10-4
DC65599 E3 ligase Ligand-Linker Conjugates 3 Featured

E3 ligase Ligand-Linker Conjugates 3 is a synthesized compound that incorporates an E3 ligase ligand and a linker used in PROTAC technology.

2101200-09-1
DC65600 42-(2-Tetrazolyl)rapamycin Featured

42-(2-Tetrazolyl)rapamycin is a prodrug compound of a rapamycin analog extracted from patent US 20080171763 A1, Example 1. Rapamycin is a specific mTOR inhibitor.

221877-56-1
DC65601 Hoechst 33342 Featured

Hoechst 33342 is a DNA minor groove binder used fluorochrome for visualizing cellular DNA.

23491-52-3
DC65602 BMS-309403 sodium Featured

BMS-309403 sodium is a potent, orally active, and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor, with Kis of <2, 250, and 350 nM for FABP4, FABP3, and FABP5, respectively. BMS-309403 sodium interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS-309403 sodium improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells.

2802523-05-1
DC65603 Mepazine Featured

Mepazine (Pecazine) is a potent and selective MALT1 inhibitor. Mepazine inhibits GSTMALT1 full length and GSTMALT1 325-760 with IC50s of 0.83 and 0.42 μM, respectively. Mepazine affects viability of ABC-DLBCL cells by enhancing apoptosis.

60-89-9
DC65604 L-Buthionine (S,R)-sulfoximine Featured

L-Buthionine-(S,R)-sulfoximine is a cell-permeable, potent, fast acting and irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels. The IC50 value of L-Buthionine-(S,R)-sulfoximine on melanoma, breast and ovarian tumor specimens are 1.9 μM, 8.6 μM, and 29 μM, respectively.

83730-53-4
DC60491 C11-MRTX Featured

C11-MRTX is a lipid-conjugated MRTX849 analogue with a 11-carbon tail. C11-MRTX is a nonaggregating potent cellular inhibitor of K-Ras(G12C).

DC65591 Pim-1 kinase inhibitor 4 Featured

Pim-1 kinase inhibitor 4 (Compound 10f) is a Pim-1 kinase inhibitor.

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